Sepsis Clinical Trial
Official title:
Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases
Change and effect of cerebral autoregulation during targeted temperature management in neurocritical patients
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | July 1, 2021 |
Est. primary completion date | July 1, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Aneurysmal subarachnoid hemorrhage (aSAH), Traumatic brain injury (TBI), Acute ischemic stroke (AIS), Intracerebral hemorrhage (ICH), Ischemic hypoxic encephalopathy (HIE), sepsis-associated encephalopathy (SAE) who need to reduce the core temperature to normal. Exclusion Criteria: - Age < 18 years old; - Pregnancy; - The temporal window was limited and the image could not be obtained; - Patients with bradycardia induced by common carotid artery compression and intolerant of THRT - Patients with severe carotid artery disease; - Uncorrected severe coagulation disorders and active bleeding; - Patients without informed consent; - Patients who had been treated with hypothermia before inclusion |
Country | Name | City | State |
---|---|---|---|
China | Xiangya Hospital Central South University | Changsha | Hunan |
Lead Sponsor | Collaborator |
---|---|
Xiangya Hospital of Central South University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | discharge mortality | Mortality of patients included in the study | mortality when patients discharge,an average of 7days |
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