HIV/AIDS, Severe Mental Illness and Homelessness
This is a two-arm randomized controlled trial (RCT) for 308 seriously mentally ill adults (SMI) engaging in risky sexual and/or drug use behavior, comparing a brief HIV primary and secondary prevention intervention [Skills building and Motivational Interviewing (SB-MI) to Care as Usual (CAU)]. The study setting is a large urban safety net Medical Center and outcomes will be measured at 3, 6, and 12 months. The SB-MI intervention (3 sessions + booster) was initially developed as the experimental condition in an R34 pilot project which demonstrated its feasibility and promise. For the proposed project, the investigators will recruit a larger sample which includes men and women with and without HIV, from various ethnic and racial groups, sexual orientations and housing arrangements, as well as a range of psychiatric disorders and functional capacities. In this way the investigators can more rigorously demonstrate the promise of SB-MI with SMI. The investigators will also conduct a sub-study after the 6 month follow-up to examine the impact at 12 months of an additional booster session for SB-MI participants. The investigators specific aims are: 1. To examine the effectiveness of a brief, tailored primary and secondary risk reduction strategy to CAU for people with serious mental illness. The desired outcomes include: - Decreased frequency of risk behaviors (number of partners, number of encounters) - Increased use of barrier precautions and IV needle cleaning - Positive changes in information and motivation, as well as risk behaviors - Increased HIV Counseling and Testing for those who do not know their HIV status 2. To examine the effectiveness of a 2nd booster session after the 6 month follow-up for ½ of participants randomized to SB-MI. The primary outcome will be: - Decreased frequency of risk behaviors and increased use of barrier precautions at the 12 month follow-up
NCT01172704 — HIV
Status: Completed
http://inclinicaltrials.com/hiv/NCT01172704/
Phase 3 Study That Assesses the Impact of a Nutrition Intervention on HIV/AIDS Infected Patients: Kingston, Jamaica
Intervention to investigate the efficacy of a nutritional supplement among ARV-naïve, asymptomatic HIV positive patients with a CD4 count in the range 300-550 cells/ul.
NCT01171495 — Human Immunodeficiency Virus (HIV)
Status: Completed
http://inclinicaltrials.com/human-immunodeficiency-virus-hiv/NCT01171495/
Behavioral Activation/Armodafinil to Treat Fatigue in HIV/AIDS
This is an integrated medication/behavioral intervention program to increase energy, activity level and goal attainment in a sample of HIV+ adults whose presenting problems include both clinically significant fatigue and unmet vocational goals. Based on previous studies, the investigators found that many patients fail to achieve desired goals even though energy is restored by medication. To address this failure of goal attainment, the investigators will evaluate a behavioral intervention, originally based on Behavioral Activation Treatment for Depression, and modified as Behavioral Activation Program for Energy and Productivity or BA-PEP. The intervention will be conducted with patients who experience clinically significant fatigue and who want to work or receive work-related training (paid or volunteer, part time or full time) or education once energy improves with medication (armodafinil).
NCT01158443 — Hiv
Status: Completed
http://inclinicaltrials.com/hiv/NCT01158443/
A New Telemedicine Approach for Chronic HIV/AIDS Patient Home Care
Background: Antiretroviral therapy has changed the natural history of the HIV infection in developed countries becoming a chronic disease. This clinical scenario would need a new approach to control patients, simplifying the follow-up visits and the accessibility to the healthcare professionals. A new home care model using a telemedicine system (Virtual Hospital) was developed.
NCT01117675 — HIV Infection
Status: Completed
http://inclinicaltrials.com/hiv-infection/NCT01117675/
HIV Treatment Adherence/Risk Reduction Integrated
HIV prevention interventions are needed to assist people living with HIV/AIDS to adhere to their medications and not transmit the virus to others. This study is testing a behavioral intervention designed to address both medication adherence and risk reduction in people living with HIV/AIDS. It is hypothesized that the experimental behavioral intervention will show improved medication adherence and safer sexual behaviors compared to a comparison group.
NCT01061021 — HIV Infections
Status: Completed
http://inclinicaltrials.com/hiv-infections/NCT01061021/
Impact of Decision Aids to Enhance Shared Decision Making for Diabetes
The proposed trial seeks to determine the impact of patient decision aids versus usual care on measures of patient involvement in decision-making, diabetes care processes, medication adherence, glycemic and cardiovascular risk factor control, and resource utilization in nonurban practices in the Midwestern United States. Upon completion of this trial, the investigators will have new knowledge about both the effectiveness of diabetes decision aids in nonacademic nonurban practices and about the processes that promote or inhibit the successful implementation of patient decision aids in such practices.
NCT01029288 — Diabetes
Status: Completed
http://inclinicaltrials.com/diabetes/NCT01029288/
Hull - Early Walking Aids for Transtibial Amputees - Does an Articulated Knee Have Benefits? A Randomised Controlled Trial
Early walking aids are routinely used in UK for rehabilitation of patients with below knee amputations. The two main walking aids used commonly in practice include the non-articulated Pneumatic Post Amputation Mobility Aid (PPAM)and the Articulated Amputee Mobility Aid (AMA). There is no published evidence on whether the articulated walking aid improves knee control and shortens delivery time. This study was designed to test the hypothesis that an articulated early walking aid has benefit to transtibial amputee compared to non-articulated early walking aid.
NCT01024023 — Unilateral Trans-tibial Amputees
Status: Unknown status
http://inclinicaltrials.com/unilateral-trans-tibial-amputees/NCT01024023/
Research on Effect of TCM on Immune Reconstitution of HIV/AIDS Patients After HAART
Chinese prescriptions can inhibit viral replication according to the course of viral replication, and the effects is similar to the effect of HAART, and even better than the anti-viral and immune reconstitution of HAART due to its effect on improve immune system function. Over the past decades, many researchers have screened the effective Chinese medicines to treat AIDS.
NCT00974454 — HIV Infections
Status: Recruiting
http://inclinicaltrials.com/hiv-infections/NCT00974454/
"Nutritional Ergogenic Aids: The Effects of Carbohydrate-Protein Supplementation During Endurance Exercise"
The purpose of this study is to assess whether the greater performance benefits from ingesting carbohydrate-protein supplements during endurance running, in comparison to the traditionally used carbohydrate supplement, is attributed to the extra calories contained in the carbohydrate-protein supplement or the presence of protein.
NCT00972387 — Supplementation During Endurance Performance
Status: Completed
http://inclinicaltrials.com/supplementation-during-endurance-performance/NCT00972387/
Developing and Testing a Tamoxifen Prophylaxis Decision Aid
RATIONALE: Evaluating a decision aid that describes the risks and benefits of taking tamoxifen citrate to prevent breast cancer may be helpful for women at increased risk of breast cancer. PURPOSE: This randomized phase I/II trial is studying tamoxifen citrate decision aids for women at increased risk of breast cancer.
NCT00967824 — Breast Cancer
Status: Completed
http://inclinicaltrials.com/breast-cancer/NCT00967824/