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Scoliosis clinical trials

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NCT ID: NCT05195580 Recruiting - Scoliosis Clinical Trials

Spine Registration Using 3D Scanning

Start date: August 31, 2021
Phase:
Study type: Observational

The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.

NCT ID: NCT05190289 Recruiting - Clinical trials for Degenerative Lumbar Spinal Stenosis

Paraspinal Muscle Degeneration, Bone Mass and Clinical Outcomes in Patients With Lumbar Degenerative Diseases

Start date: April 3, 2021
Phase:
Study type: Observational

This study was a retrospective study. The investigators intended to review the preoperative paraspinal muscle imaging data of patients with lumbar spinal stenosis and degenerative scoliosis treated in hospital, and follow up the symptoms, quality of life and surgical complications at 1 year and at the last follow-up. The aims were: (1) to explore the correlation between paraspinal muscle imaging parameters and clinical outcomes; (2) based on the postoperative functional scores and the presence of complications, to explore the best combination of imaging parameters for predictive value of prognosis; (3) to evaluate the consistency between different measurement methods, and improve the standardized paraspinal muscle imaging assessment; (4) Combining the characteristics of individual bone mass and paravertebral muscle (functional and imaging assessment), to explore the correlation between bone loss and paravertebral muscle degeneration; (5) to explore a muscle-bone mass assessment system that could reflect the prognosis of patients.

NCT ID: NCT05187780 Recruiting - Healthy Clinical Trials

Comparison of Reposition Sense in Scoliosis and Healthy Adolescents

Start date: January 22, 2022
Phase:
Study type: Observational

The aim of the study is to compare the spine joint reposition sense in adolescent idiopathic scoliosis and healthy adolescents and to investigate whether there is a difference.

NCT ID: NCT05159505 Recruiting - Scoliosis Clinical Trials

Interdisciplinary Scoliosis Correction Program.

Start date: December 1, 2021
Phase:
Study type: Observational

The aim of this study is to compare the outcomes after scoliosis surgery before and after the implementation of an interdisciplinary juvenile scoliosis correction program in teenager based on ERAS (enhanced recovery after surgery) principles.

NCT ID: NCT05152329 Recruiting - Scoliosis Clinical Trials

Investigating the Potential Psychological Impact of Early Screening and Long-term Monitoring for Adolescent Idiopathic Scoliosis Among Patients and Caregivers

Start date: February 1, 2021
Phase:
Study type: Observational

Adolescent Idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine of unknown aetiology, characterised by a lateral curvature and vertebral rotation. Its prevalence is estimated to be 2.5% in children between aged 10 and 16 in Hong Kong. Despite concerns regarding the psycho-social issues patients face at and after AIS screening, there is no study that directly address this subject. The investigator propose to conduct a prospective longitudinal study on the psycho-social impact of AIS early screening and long-term monitoring amongst patients and their caregivers. The proposed study will bridge this research gap by evaluating a cohort of newly-diagnosed patients with AIS through the school screening program and their caregivers. A mixed-methods research approach to tap into the distinct social, behavioural, emotional and parental experiential profiles will be used. Patterns across different profiles can enhance the investigator's understanding of which aspects of AIS early screening and long-term monitoring can adversely affect patients' psychological well-being. Findings will facilitate targeted approaches to address specific psycho-social impact of scoliosis and its treatment, heighten compliance to long-term monitoring and prevention of scoliosis progression, and mobilise a new clinical care model that addresses patient and clinician concerns.

NCT ID: NCT05146193 Recruiting - Spinal Deformity Clinical Trials

AI-Powered Scoliosis Auto-Analysis System Multicenter Development and Validations

Start date: May 1, 2022
Phase:
Study type: Observational

The investigators aim to use artificial intelligence (AI) to help clinicians in diagnosing and assessing spinal deformities.

NCT ID: NCT05145725 Recruiting - Clinical trials for Scoliosis; Adolescence

Instrumented POsterolateral Arthrodesis for Adolescent Idiopathic Scoliosis

APOSIA
Start date: March 18, 2021
Phase:
Study type: Observational

The study population concerns adolescent patients with idiopathic scoliosis which requires surgical management and who have a longer waiting period of 6 months. The aim of this study is to research the predictive factors of an improvement in the quality of life of adolescents who have had surgery.

NCT ID: NCT05138393 Recruiting - Clinical trials for Idiopathic Scoliosis

Scoliosis-specific Exercises for Mild Idiopathic Scoliosis

Start date: February 18, 2022
Phase: N/A
Study type: Interventional

Idiopathic scoliosis is the most common spinal deformity in children and adolescents with an estimated prevalence of 3%. About one tenth of the children with scoliosis develop a deformity that requires treatment with brace or surgery with the current treatment protocol. In Sweden, mild scoliosis curves not requiring treatment, but at risk for progression during childhood, are only observed until skeletal maturity without active treatment. If progression occurs and treatment is required, standard treatment consists of bracing 20 hours or more per day. Scoliosis-specific exercises have been reported to be a possible treatment modality in terms of halting progression in mild scoliosis, but the findings are not generally accepted.

NCT ID: NCT05128279 Recruiting - Clinical trials for Idiopathic Scoliosis

Adolescent and Young Adulte Scoliosis

AIS
Start date: October 28, 2020
Phase:
Study type: Observational

Thoracic hypocyphosis and greater lumbar lordosis after correction of idiopathic scoliosis in adolescents and young adults may adversely affect overall sagittal alignment and increase the risk of proximal junctional kyphosis. The objective of this study is to analyze surgical corrections and maintenance of correction over time using modern posterior instrumentation strategies by comparing technical developments.

NCT ID: NCT05116436 Recruiting - Clinical trials for Scoliosis Idiopathic

Genetic Study of Idiopathic Scoliosis in a Cohort of Families (SCOGEN)

SCOGEN
Start date: June 6, 2020
Phase:
Study type: Observational

This study will focus on a large cohort of multiplex families, to precisely identify candidate genes. The fact of have a large database (fifty families, collected by the principal investigator for more than two decades), will contribute to the discovery of genes of interest. It will also allow testing for the presence or absence of mutations found in other cohorts in previous studies. The main objective of this study is to identify genetic abnormalities associated with the presence and severity of idiopathic scoliosis, in families of scoliosis.