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Scoliosis clinical trials

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NCT ID: NCT05105737 Recruiting - Clinical trials for Degenerative Scoliosis

Degenerative Scoliosis

DS
Start date: October 29, 2020
Phase:
Study type: Observational

Several deformities of the spine exist such as degenerative lumbar scoliosis. These deformities can generate functional discomfort and limit the patient's quality of life. In the event of severe trunk imbalance and progression of the deformity, operative correction of the spinal deformity by instrumentation and posterior arthrodesis may be indicated. Surgical techniques and instrumentation have evolved over the past 5 years. These changes in surgical strategies have a potential impact on the patient's quality of life and the correction results in the medium and long term. The aim of the study is the analysis of surgical corrections obtained and radiological changes over time with classic 2-rod techniques versus modern 4-rod instrumentation techniques

NCT ID: NCT05071144 Recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Spine Procedures Assisted With RoboTics And Navigation

SPARTAN
Start date: December 13, 2021
Phase:
Study type: Observational [Patient Registry]

Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation in pediatric spine deformity surgery across participating study institutions. Eventually, an educational and informative framework for this technology will be established.

NCT ID: NCT05051254 Recruiting - Lung Diseases Clinical Trials

Respiratory Muscles and Work of Breathing in Children

WOB&MR_Ped
Start date: January 19, 2022
Phase: N/A
Study type: Interventional

Respiratory muscle testing allows a quantitative assessment of inspiratory and expiratory muscles in children of any age with primary or secondary respiratory muscle impairment, in order to better understand the pathophysiology of respiratory impairment and guide therapeutic management. The use of an invasive technique (esogastric probe) makes it possible to specifically explore the diaphragm, the accessory inspiratory muscles and the expiratory muscles in order to detect dysfunction or paralysis of these muscles, and to estimate the work of breathing in order to better guide the respiratory management. The primary objective of the study is to evaluate the respiratory effort in children with primary or secondary impairment of the respiratory muscles during spontaneous breathing or during mechanical ventilation.

NCT ID: NCT05045014 Recruiting - Clinical trials for Scoliosis Idiopathic

Evaluation of Vestibular Dysfunction or Visuospatial Perception in Individuals With Idiopathic Scoliosis

Start date: November 30, 2021
Phase:
Study type: Observational

This study was planned to investigate whether there is a visual-spatial perception disorder in individuals with idiopathic scoliosis and also to reveal its dependent/independent relationship with vestibular dysfunction.

NCT ID: NCT05011734 Recruiting - Clinical trials for Scoliosis Idiopathic

Rapid Postoperative Recovery Pathway in Adolescent Idiopathic Scoliosis.

Start date: November 3, 2021
Phase:
Study type: Observational

the study will evaluate the clinical outcomes of an intra- and postoperative fast-track protocol in patients undergoing instrumented posterior arthrodesis surgery for adolescent idiopathic scoliosis.

NCT ID: NCT04960423 Recruiting - Clinical trials for Degenerative Scoliosis

Clinical Study of Imaging and Endoplant-related Mechanical Complications After Long Segment Fixation and Fusion of Degenerative Lumbar Scoliosis (DLS)

Start date: January 1, 2020
Phase:
Study type: Observational

There is a high probability of mechanical complications in patients with degenerative lumbar scoliosis after long segment fixation and fusion, and there are few studies on distal borderline kyphosis deformity/failure. This study was designed to retrospectively analyze the patients with degenerative lumbar scoliosis (DLS) who underwent posterior selective decompression and long segment fixation and fusion surgery in the lumbar spine department of our hospital from April 2009 to May 2016. Patients' basic data, surgical data and preoperative, immediate postoperative and follow-up imaging data were collected to study the incidence of distal mechanical complications, risk factors and their relationship with clinical symptom scores in DLS patients undergoing posterior selective decompression and long segment fixation and fusion. It has guiding significance for clinical operation decision making.

NCT ID: NCT04950660 Recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion

Start date: December 11, 2019
Phase: Phase 4
Study type: Interventional

Prospective, randomized control trial To determine if oral caffeine decreases the frequency of opioid demand in children with adolescent idiopathic scoliosis after their spinal fusion surgery To compare pain scale ratings, number of requests for diazepam, average heart rate, average blood pressure, sex, age, ethnicity, post-op day of discharge, operative time, estimated intraoperative blood loss, remittance post-surgery, length of hospital stay, and segments fused during spinal fusion surgery.

NCT ID: NCT04945343 Recruiting - Clinical trials for Early-Onset Scoliosis Deformity of Spine

Long-Term Follow-Up Of Surgical Management Of Early Onset Scoliosis Using Growing Rods

Start date: June 2021
Phase: N/A
Study type: Interventional

The aim of this work is to evaluate the long-term outcome of the graduates (those who completed the gradual lengthening procedures), to better understand the full scope and natural course of Growing Rods treatment for EOS and to have a glimpse of what happens to the graduates.

NCT ID: NCT04922983 Recruiting - Clinical trials for Scoliosis Idiopathic

Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis

Start date: July 1, 2021
Phase: Phase 2
Study type: Interventional

The study uses a yoga-like isometric posture and botulinum injections to reduce the curves in adolescent idiopathic lumbar scoliosis. Three previous studies show that the yoga pose is effective for reversing scoliotic curves; Botulinum toxin has been approved by the FDA for teenagers. However, no studies using the two of them together have been done until this one.

NCT ID: NCT04914507 Recruiting - Clinical trials for Scoliosis Idiopathic

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

Start date: September 9, 2021
Phase: N/A
Study type: Interventional

Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE). The goal of AVBT is to control curve progression by applying compression on the convex side of the spine deformity. While there has been great initial enthusiasm about the technique as an alternate treatment option to spinal fusion for skeletally immature children with scoliosis, there is a need to better understand the long-term outcomes. The purpose of this study is to report the long-term clinical outcomes of skeletally immature patients treated with AVBT, specifically: 1. The effect on three-dimensional spine growth as compared to normal controls 2. Maintenance of major Cobb angle less than or equal to 50 degrees at skeletal maturity 3. Complications associated with both the procedure and the device