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Scoliosis clinical trials

View clinical trials related to Scoliosis.

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NCT ID: NCT06357234 Not yet recruiting - Anesthesia Clinical Trials

Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery

Start date: June 2024
Phase: Phase 2
Study type: Interventional

This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).

NCT ID: NCT06347419 Not yet recruiting - Clinical trials for Scoliosis Idiopathic

Body Awareness and Spinal Stability in Scoliosis

Start date: April 30, 2024
Phase:
Study type: Observational

Thirty volunteer patients diagnosed with scoliosis by a specialist physician at Gazi University Hospital Orthopedics and Traumatology Department and subsequently referred to Gazi University Physiotherapy and Rehabilitation Department for exercise training will be included in the study. The lumbar Pressure Measurement Test with Stabilizer and Rotation Stability Tests will be utilized to evaluate the spinal stability of the patients. Body awareness will be assessed using the Body Awareness Survey, comprising 18 questions. All assessments will be conducted at the Orthopedic Rehabilitation Clinic within the relevant department. The results obtained from this study will elucidate the relationship between body awareness and spinal stability in individuals with scoliosis.

NCT ID: NCT06341465 Not yet recruiting - Scoliosis Clinical Trials

Investigation of the Effects of Exercise and Kinesiological Taping on Spinal Deformities and Serum Markers in Individuals With Scoliosis

Start date: April 4, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of Schroth exercises and kinesiological taping on spinal deformities and serum markers in young adults with scoliosis. The study will include young adults aged 18-21 with scoliosis. A total of 57 participants will be included in the study. Out of 57 participants, 38 have scoliosis, and 19 are healthy. 38 participants will be randomly divided into 2 groups. One group (n=19) will receive only Schroth exercises, and the other group (n=19) will receive both Schroth exercises and kinesiological taping. The laboratory analyses of proteins associated with autophagy (Beclin-1, LC3, and ATG3) and bone-cartilage metabolism (COMP and MMP-3) will be conducted in the Biomedical Engineering Laboratory of our university. Trunk rotation will be assessed using the Adams Forward Bend Test with scoliometer, quality of life will be evaluated with the SRS-22 Quality of Life questionnaire and Quality of life profile for spinal deformities questionnaire, perception of deformity will be measured using the Walter Reed Visual Assessment Scale, and Cobb angles will be evaluated from anterior-posterior X-ray images.

NCT ID: NCT06301984 Not yet recruiting - Clinical trials for Early Onset Scoliosis (EOS)

Safety and Efficacy Evaluation of Insight GS Growing System

Start date: July 2024
Phase: Phase 3
Study type: Interventional

Premarket, interventional, single-arm clinical study, to evaluate the safety and efficacy of Insight GS Growing System in the surgical treatment of Early Onset Scoliosis (EOS). Also, to evaluate the difference in height of the spine and trunk, the success rate of the procedure, monitor adverse events and evaluate the satisfaction of the patient and care providers. The Andromeda Insight Growing System (Insight GS) is intended to treat severe, progressive multi-planar spinal deformities such as early-onset scoliosis while allowing for skeletal growth. The Andromeda Insight Growing System consists of blades, clamps and pedicle screws used to form a distinct spinal construct in growing children. The implanted blade is used to brace the spine during growth and minimize the progression of scoliosis. The components are implanted from a posterior approach and are made from Titanium alloy (Ti6AL-4V-ELI), and High Density Polyethylene (HDPE). Patients from 3 to 10 years of age, or who are still skeletally immature, who present early-onset scoliosis and who are considered as able to receive the surgical procedure with the Insight GS system, will be included in the study. Patients will be screened in the outpatient setting of the study site. All participants who meet the eligibility criteria will be invited to participate in the study, which includes screening/pre-op, surgery to install the Insight GS system, and follow-up visits at 6 weeks, 2, 4, 6, 8, 10, 12,. 18 and 24 months for data collection, clinical evaluation, imaging, and monitoring of adverse events.

NCT ID: NCT06298812 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

REFLECT Scoliosis System Post Approval Study

Start date: March 31, 2024
Phase: N/A
Study type: Interventional

The purpose of this multi-center, prospective, single-arm registry Post-Approval Study (PAS) is to evaluate the radiographic and clinical outcomes of 100 patients with idiopathic scoliosis treated with the REFLECTâ„¢ Scoliosis Correction System, as a condition of HDE approval

NCT ID: NCT06295991 Not yet recruiting - Clinical trials for Respiratory Function Test

The Effect of Lycra Garments on Spastic Diplegic Cerebral Palsy Patients With Scoliosis

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The primary aim of this study was to investigate the effects of lycra clothing on balance and respiratory functions in individuals with cerebral palsy with scoliosis, and the secondary aim was to investigate the effects of lycra clothing on motor function, activity limitation and quality of life in these individuals.

NCT ID: NCT06290843 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

Analysis of Body Balance Parameters in Children With Idiopathic Scoliosis

Start date: April 5, 2024
Phase:
Study type: Observational

The aim of the study is to compare body balance parameters assessed using the AMTI dynamometric platform in children with idiopathic scoliosis (with and without Schroth therapy) compared to control group.

NCT ID: NCT06277089 Not yet recruiting - Scoliosis Clinical Trials

Curve Correction of Early Onset Scoliosis by Mehta Serial Casts

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Assessment of the role of Mehta Serial Casts in Curve Correction of Early Onset Scoliosis

NCT ID: NCT06258161 Not yet recruiting - Scoliosis Clinical Trials

Effect of Adult Spinal Deformity Surgery on Functional Reach

Start date: March 2024
Phase:
Study type: Observational

Adult spinal deformity (ASD) is a common spinal condition that often impacts an individual's ability to stand and maintain an upright posture. Poor balance often limits an individual's ability to perform basic activities of daily life (ADL) and can lead to disability. Current considerations of correcting ASD to improve balance focus on the amount of sway that one exhibits during normal standing. However, current tests do not provide insight into the limits of balance during normal ADL. The goal of this research is to develop a new balance assessment that includes a functional reach test (FRT) to provide numerical data on the limits of one's ability to maintain balance. The study will include both ASD patients and matched healthy adults and will compare postural sway measures between them. Wearable motion tracking sensors and a force plate will be used to monitor body movement and changes in the center of pressure under foot during normal standing and during a FRT. Data from this study will inform spine surgeons of ASD patient's risk of balance loss in daily life and enable further research on the effects of surgical techniques to restore balance among ASD surgery patients.

NCT ID: NCT06242821 Not yet recruiting - Scoliosis Clinical Trials

Back Pain Management in AIS: Yoga vs Physical Therapy

AIS
Start date: June 25, 2024
Phase: N/A
Study type: Interventional

Targeting non-operative Adolescent Idiopathic Scoliosis (AIS) patients, including those who are braced and non-braced, this research project at Johns Hopkins Hospital seeks to revolutionize the treatment approach for Adolescent Idiopathic Scoliosis. This innovative study compares traditional physical therapy with a yoga-based intervention, focusing on alleviating back pain and enhancing quality of life in this specific patient group. This research is anchored in substantial existing evidence that highlights the physiological and psychological benefits of yoga and is in alignment with current AIS treatment strategies. Addressing the urgent need for diverse non-operative management strategies for AIS, this study is particularly timely given the challenges in accessing physical therapy and the growing concerns over opioid use. The investigators exploration of structured yoga protocols aims to introduce a viable alternative therapy, providing significant relief and improving the quality of life for AIS patients who are not candidates for surgery. By integrating cutting-edge healthcare solutions with the increasing interest in yoga in the U.S., this project aims to establish a new benchmark in non-surgical AIS treatment that is both effective and accessible to a wide range of patients