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Respiratory Function Tests clinical trials

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NCT ID: NCT06359145 Recruiting - Clinical trials for Pulmonary Disease, Chronic Obstructive

Prediction of COPD Severity Using Electrical Impedance Tomography

Start date: April 1, 2023
Phase:
Study type: Observational

The purpose of this study is to predict the CT visual score of emphysema with EIT-based parameters, in order to provide a non-invasive and convenient method for the evaluation of lung structure and physiological and pathological progression of COPD.

NCT ID: NCT06207331 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease

Start date: October 28, 2023
Phase: N/A
Study type: Interventional

Studies have shown that intravenous infusion and nebulized dexmedetomidine can improve lung function in mechanically ventilated patients, including those with preoperative COPD, exerting lung protection. However, these studies are based on mechanical ventilation patients under general anesthesia, and more intuitive research is needed on whether dexmedetomidine can also exercise pulmonary precaution in awake patients. Pulmonary function monitoring is the most direct way to evaluate changes in lung function in awake patients. Portable pulmonary function machines can assess lung function in a variety of settings. In addition, compared with intravenous administration, nebulized inhalation administration directly acts on the mucosa of the respiratory tract, does not involve invasive operations, and has higher safety and comfort. Therefore, this study intends to use portable pulmonary function instruments and non-invasive ambulatory respiratory monitors to evaluate the effect of nebulized dexmedetomidine on lung function in COPD patients to guide the perioperative management of COPD patients.

NCT ID: NCT05847127 Enrolling by invitation - Clinical trials for Respiratory Function Tests

Is There a Difference in Pulmonary Functions and Craniovertebral Angle Among Adolescent Based on Smart Phone Usage

Start date: February 28, 2023
Phase:
Study type: Observational

The smartphones have become a necessity for most adolescents as they are used for communication and entertainment and education purposes especially in the period of COVID pandemic. They spend most of their time in using smartphones. This could have side effects on their health. While using a smartphone, adolescent usually flex their neck and maintain the head in a forward position for long periods of time, which may affect the craniovertebral angle and pulmonary functions as sustained forward neck posture may lead to respiratory dysfunction.The purpose of the study is to investigate the effect of smart phones and tablets usage time on craniovertebral angle and problems of pulmonary functions among adolescents between 14-18 years' old.

NCT ID: NCT05812196 Recruiting - Long COVID Clinical Trials

Late Respiratory Consequences of SARS-CoV-2 Pneumonia

Start date: January 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about the respiratory system in post-COVID syndrome. The main question aims to answer: how the post-COVID syndrome alters the lung function Participants will be asked to perform lung function tests. Researchers will compare post-COVID group to matched control healthy individuals.

NCT ID: NCT05793723 Recruiting - COVID-19 Clinical Trials

Long-term Respiratory Complications in Infants With Perinatal COVID-19

COLF
Start date: June 7, 2022
Phase:
Study type: Observational

Study outcomes and endpoints: - Primary outcome: to assess clinical characteristics of infants with confirmed COVID-19 infection at birth and to evaluate long-term respiratory consequences of neonatal COVID-19 infection. - Secondary outcome: to evaluate the prevalence and natural history of lung function impairment among infants with confirmed COVID-19 compared to infants with no history of COVID-19. To this end, infants will undergo pulmonary function testing (PFT) with the Exhalyzer D device (Eco Medics, Switzerland).

NCT ID: NCT05459116 Recruiting - Clinical trials for Respiration, Artificial

Visualization of Inspiratory Effort and Respiratory Mechanics to Promote Lung- and Diaphragm Protective Ventilation

VIREM
Start date: September 21, 2022
Phase: N/A
Study type: Interventional

This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm. The investigators will daily (for a maximum of 8 days) measure esophageal pressures with a balloon catheter to quantify inspiratory effort and respiratory muscle function, and perform daily ultrasound measurements of the diaphragm and the lungs. The investigators hypothesize that a small inspiratory effort will result in the preservation of diaphragm function and have no adverse effect on lung function.

NCT ID: NCT05276986 Completed - Exercise Clinical Trials

Effects of Delayed Muscle Pain on Respiratory Muscle Function

Start date: November 17, 2019
Phase: N/A
Study type: Interventional

The aim of the study was to determine whether delayed-onset muscle soreness (DOMS) in trunk muscles has an effect on respiratory function parameters, respiratory muscle strength, respiratory muscle endurance, and exercise capacity.

NCT ID: NCT04741373 Recruiting - Body Composition Clinical Trials

Study on Pulmonary Rehabilitation for Stable Chronic Obstructive Pulmonary Disease(COPD) Patients

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

To compare the difference of effectiveness for stable COPD patients with poor nutritional status among three groups named health education, upper and lower limb exercises, and oral nutritional supplements. Then formulate the best pulmonary rehabilitation guidance strategy according to the result of this trial.

NCT ID: NCT04697251 Recruiting - Respiratory Disease Clinical Trials

Infant Forced Oscillations Technique (iFOT)

iFOT
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is the implementation of Forced Oscillations Technique (FOT) in newborns and small infants using a novel commercially available device. The objective is to assess the feasibility of the method, provide normative data for the first months of life and describe short- and long-term changes in neonatal respiratory disorders. The study population will consist of term and preterm newborns admitted to the Neonatal Intensive Care Unit (NICU) or the Well-Baby Nursery of the University Hospital of Patras, Greece. It is estimated that 200 full-term and 150 preterm newborns will be enrolled during a period of 36 months (March 2021 - September 2022). Measurements will be performed using the TremoFlo N-100 via a face mask, with the infant in the supine position during natural sleep. At least 3 technically acceptable measurements (duration 10s each) will be obtained, as follows: - Healthy full-term neonates: postnatal days 1, 2, 3 and at discharge - Preterm neonates: NICU admission, postnatal days 1, 2 and 3, and on the first day of each additional gestational week until discharge All participants will be also measured at the age of 3, 6 and 12 months.

NCT ID: NCT04122040 Completed - Quality of Life Clinical Trials

Effects of Roxithromycin on Quality of Life and Physiological Outcomes in Bronchiectasis

Start date: March 1, 2011
Phase: Phase 3
Study type: Interventional

roxithormycin 300 mg per day for 12 weeks could improve quality of life and physiological outcomes in bronchiectasis