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Recurrence clinical trials

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NCT ID: NCT05545124 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Study of Donafenib Combined With Tislelizumab in the Adjuvant Treatment of Primary HCC With High Risk of Recurrence

Start date: November 2022
Phase: Phase 2
Study type: Interventional

To explore the safety and preliminary efficacy of donafenib combined with tislelizumab in adjuvant therapy after radical surgical resection of primary hepatocellular carcinoma with high risk of recurrence.

NCT ID: NCT05540275 Not yet recruiting - Clinical trials for Recurrent Glioblastoma

Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma

Start date: October 5, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the clinical efficacy and safety of Tislelizumab (one anti-PD-1 antibody same as nivolumab approved in China) in combination with bevacizumab in patients with recurrent or progressive glioblastoma (GBM) who have progressed on bevacizumab with or without PTEN or TERT gene mutations.

NCT ID: NCT05526209 Not yet recruiting - Ventral Hernia Clinical Trials

Longitudinal Relaxing Incision as a Technique for Recurrence Prevention in Ventral Hernia

Start date: September 1, 2022
Phase:
Study type: Observational

The aim of the study is showing the efficiency of using Longitudinal relaxing incision as a Technique for recurrence prevention in Ventral Hernia

NCT ID: NCT05520112 Not yet recruiting - Clinical trials for Recurrent Pregnancy Loss

Treatment of Recurrent Pregnancy Loss Using Mesenchymal Stem Cells

Start date: November 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Treatment of Recurrent pregnancy loss using mesenchymal stem cells capable of differentiation in the endometrial-decidual direction.

NCT ID: NCT05514314 Not yet recruiting - Clinical trials for Non-Small Cell Lung Cancer

A Multicenter Prospective Study to Assess the Effects of Adjuvant Icotinib in EGFRm Stage I NSCLC With High-risk of Disease Recurrence After Complete Resection

Start date: September 1, 2022
Phase: Phase 2
Study type: Interventional

This is a multicenter single arm study, with an aim to assess the effects of adjuvant icotinib among EGFR mutant stage I lung adenocarcinoma patients, who have high-risk pathological features of recurrence.

NCT ID: NCT05510167 Not yet recruiting - Atrial Fibrillation Clinical Trials

Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF

PLATINUM
Start date: August 22, 2022
Phase: N/A
Study type: Interventional

Earlier studies have shown a dose-dependent relationship between alcohol intake and incident atrial fibrillation (AF) as well as a causal link with several risk factors for AF such as hypertension, obesity and sleep apnea. However, the effect of drinking (alcohol) on post-ablation outcome such as arrhythmia recurrence, quality of life (QoL) and cognitive function in AF patients is unclear. Therefore, we aim to find the answer for a very frequently asked question, "is it safe to continue drinking alcohol (at the pre-ablation level) following catheter ablation OR should the intake be reduced for better outcome?", in this randomized trial.

NCT ID: NCT05504512 Not yet recruiting - Kidney Diseases Clinical Trials

Percutaneous Nephroscopic Treatment of Parapelvic Cysts

Start date: November 30, 2022
Phase:
Study type: Observational

Background of the project: The surgical treatment of parapelvic cysts is currently less researched and there is no gold standard for surgery. Previously, in percutaneous nephrolithotomy, we found that fenestration and fenestration drainage in the simultaneous treatment of pararenal pelvis cysts under nephroscopic nephroscopic surgery has clear curative effect, less trauma, and quicker recovery. Objective: To clarify the safety, efficacy and long-term efficacy of percutaneous nephroscopy in the treatment of parapelvic cysts. Nature: Retrospective case cohort study. Basic research process: Retrospective collection of cases in our hospital who underwent percutaneous nephroscopy for the treatment of parapelvic cysts, and comparison of preoperative and postoperative cyst size changes and long-term efficacy.

NCT ID: NCT05492760 Not yet recruiting - Atrial Fibrillation Clinical Trials

Evaluation of Recurrence Risk of Atrial Fibrillation After Cryoballoon Ablation

era-cryo
Start date: August 1, 2022
Phase:
Study type: Observational

The recurrence of atrial fibrillation(AF) after pulmonary vein ablation with cryoballoon is conducted by many factors . The previous studies found larger left atrial and longer AF duration are tied to higher risk of AF recurrence. The characters of ablation procedure is also of critical importance to durable clinical success such as temperature features and time-to-isolation (TTI). The aim of our study is to develop an tool of recurrence risk evaluation with both pre-procedure and procedure factors.

NCT ID: NCT05489289 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

A Phase III Study of AK104 as Adjuvant Therapy in HCC With High Risk of Recurrence After Curative Resection

Start date: September 24, 2022
Phase: Phase 3
Study type: Interventional

The efficacy and safety of AK104 as adjuvant therapy in hepatocellular carcinoma of high recurrence risk after curative resection.

NCT ID: NCT05461664 Not yet recruiting - Clinical trials for Gastrointestinal Stromal Tumors

Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA

Start date: July 10, 2022
Phase:
Study type: Observational

This is a prospective, multicenter, observational real-world study to explore the Avapritinib therapy in GIST patients who definited Non-exon18 Mutations of PDGFRA.