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Radiation Therapy clinical trials

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NCT ID: NCT04868097 Recruiting - Radiation Therapy Clinical Trials

Predicting Adjuvant Post-operative Radiation Therapy in Patients With Cervical Cancer Stage IB2

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

A pre- operative evaluation for the presence of intermediate risk factors prior to surgery may allow for better patient counselling, modify the course of surgery or select patients to undergo primary chemo- radiation. The purpose of this study is to validate that the presence of histological risk factors in a pre-operative large loop biopsy highly correlates with post-operative histological evaluation and the subsequent indication for post-operative chemo-radiation

NCT ID: NCT04443400 Recruiting - Radiation Therapy Clinical Trials

Early Detection of Cardiac Damage by Two‑Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to detecte and predict early subclinical cardiac damage induced by thoracic radiation therapy based on two‑dimensional speckle tracking echocardiography combined with multiple circulating biomarkers.

NCT ID: NCT04362306 Recruiting - Anxiety Clinical Trials

Radiation Oncology Patient Medical Physics Intervention Study

Start date: March 3, 2020
Phase: N/A
Study type: Interventional

This investigation is designed to be a two-arm, non-randomized prospective phase 2 study evaluating the impact of medical physicist patient intervention on the anxiety level and patient satisfaction of patients undergoing a course of radiation therapy. The goal is to demonstrate that these interventions will have a significantly positive impact on the overall well-being of the oncology patients.

NCT ID: NCT03731130 Recruiting - Quality of Life Clinical Trials

Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer

NEOCARE
Start date: October 5, 2018
Phase:
Study type: Observational

Observational study to evaluate longitudinal quality of life according to standardized EORTC questionaires as well as functional Outcome, oncological outcome and toxicity in patients treated with neoadjuvant short term radiation or long-term chemoradiation followed by surgery

NCT ID: NCT03213925 Recruiting - Breast Cancer Clinical Trials

Neoadjuvant Chemotherapy Followed by Radiotherapy Alone in Patients With Breast Cancer

Start date: June 1, 2017
Phase: Phase 2
Study type: Interventional

After neoadjuvant chemotherapy, patients normally receive either conservative breast surgery or mastectomy followed by radiation therapy. Some patients achieve a complete response after neoadjuvant chemotherapy. Considering that radiation therapy is an effective treatment for subclinical microscopic disease, the question arises whether breast surgery before radiation therapy can be avoided in the subgroup of patients with complete response after neoadjuvant chemotherapy.

NCT ID: NCT03142425 Recruiting - Radiation Therapy Clinical Trials

Blood Test to Predict Radiation Response and Toxicity in Patients Undergoing Radiation Therapy

Start date: June 19, 2017
Phase:
Study type: Observational

Collect blood samples and associated clinical data prior to and post radiation treatment.

NCT ID: NCT03133286 Recruiting - Cancer Clinical Trials

Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)

RADIANT
Start date: April 6, 2017
Phase:
Study type: Observational

Collect blood samples and associated clinical data prior to, during, and post radiation treatment.

NCT ID: NCT03071289 Recruiting - Cervical Cancer Clinical Trials

A Trial Comparing Observation With Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer

Start date: June 1, 2017
Phase: Phase 3
Study type: Interventional

Cervical cancer of early stage is treated mainly by radical resection and (or) radiotherapy. And pelvic lymphocyst is one of the most common adverse events of radical resection. The aim of this study is to compare observation with radiation on pelvic lymphocyst of cervical cancer patients after radical resection, for incidence of adverse events and local recurrence rate.

NCT ID: NCT02422550 Recruiting - Radiation Therapy Clinical Trials

Imaging Acquisition and Analysis Methods for Optimization of MRI Radiation Oncology Simulation and Response Assessment

Start date: April 9, 2015
Phase:
Study type: Observational

Magnetic resonance imaging (MRI) is currently one of the standard diagnostic imaging methods used to diagnose tumor stage before treatment in the Radiation Oncology Department. It is also used to check responses to radiation after treatment. However, MRI isn't traditionally used in planning for radiation treatment or in checking treated tumor and tissue changes during radiation treatment. The goal is to find out the possible benefits of MRI imaging techniques in these settings of radiation treatment. The research aims are to study the possibility of using devices with new abilities such as the MR-Linac. The MR-Linac combines a radiation treatment machine with a diagnostic MRI scanner. This device will improve the quality of MRI-guided radiation treatment. The MR-Linac has functions that are currently not available in other combined imaging and radiation delivery devices. The MR-Linac does not provide additional imaging capabilities that are not currently available in other imaging devices. Participating in this study would NOT change the current treatment plans, this will allow the investigators to use the MRI methods in research and future patient care.