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Evaluation of dAroLutamide Addition to anDrogen Deprivation Therapy and radIatioN Therapy in Newly Diagnosed Prostate Cancer With Pelvic Lymph Nodes Metastases — ALADDIN  

Prostate Cancer Clinical Trial

Official title:
Evaluation of dAroLutamide Addition to anDrogen Deprivation Therapy and radIatioN Therapy in Newly Diagnosed Prostate Cancer With Pelvic Lymph Nodes Metastases

Clinical Trial Summary

Prospective, multicenter, comparative, randomized placebo-controlled Phase III trial - patients with hormone-naïve prostate cancer and pelvic lymph nodes metastases

Clinical Trial Description

Standard of care for patients with prostate cancer (PC) with pelvic lymph nodes metastases is radiotherapy (RT) with long-term androgen deprivation therapy (ADT). . Darolutamide improves survival in men with castration-refractory non metastatic prostate cancer. We hypothesize that adding Darolutamide to ADT and RT could improve FFS for these high-risk patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05116475
Study type Interventional
Source Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie
Contact Ishak Senouci
Phone 0766185461
Email ishak.senouci@association-artic.org
Status Recruiting
Phase Phase 3
Start date August 30, 2022
Completion date February 2027
View Details
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