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Clinical Trial Summary

The purpose of this research study is to measure the hypoxia (low oxygen condition) in prostate cancers and its effect in survival. In this study, investigators will assess hypoxia by magnetic resonance imaging (MRI) and create a hypoxia score. Investigators will study the hypoxia score and how it correlates (if any) to the disease aggressiveness as well as its effect on the treatment outcomes.


Clinical Trial Description

Primary Objective(s): - To assess hypoxia in primary prostate tumors by magnetic resonance imaging. - To correlate hypoxic score with disease aggressiveness (proliferation biomarkers' expression). Secondary Objective(s): - To correlate hypoxic score with ExoHypoxic concentration in plasma of same patient. - To correlate hypoxic score with fatty acid synthase (FASN) expression. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03987568
Study type Interventional
Source Wake Forest University Health Sciences
Contact
Status Withdrawn
Phase N/A
Start date July 10, 2019
Completion date November 15, 2021

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