Prostate Cancer Clinical Trial
Official title:
The Study on the Spatial Distribution of Prostate Cancer by Modified Trans-perineal Template-guided Mapping Biopsy
Investigators plan to use modified TTMB technology to puncture prostate of participants suspected prostate cancer, especially those with the first negative biopsy , but having a rising PSA.Then, Investigators will simulate the spatial distribution of prostate cancer in patients with positive biopsy before radical prostatectomy by way of the TPS software system . And after the radical prostatectomy ,Investigators will simulate the spatial distribution with the help of large tissue slice technique to compare with preoperative simulation ,which to verify the two simulations are consistent.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | December 31, 2019 |
Est. primary completion date | December 31, 2018 |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 18 Years to 90 Years |
Eligibility |
Inclusion Criteria: 1.Male patients; 2.18 yrs and older, and 90 yrs and younger; 3.Rectal examination reveal prostate nodules; 4.B ultrasound, CT or MRI find abnormal images; 5.PSA>4ng/ml, abnormal f/t ratio and PSAD Exclusion Criteria: 1. Abnormal coagulation function; 2. Severe urinary tract infection; 3. Serious cardiovascular and cerebrovascular disease |
Country | Name | City | State |
---|---|---|---|
China | Subei People's Hospital of Jiangsu province | Yangzhou | Jiangsu |
Lead Sponsor | Collaborator |
---|---|
Subei People's Hospital of Jiangsu Province |
China,
Tran M, Thompson J, Böhm M, Pulbrook M, Moses D, Shnier R, Brenner P, Delprado W, Haynes AM, Savdie R, Stricker PD. Combination of multiparametric MRI and transperineal template-guided mapping biopsy of the prostate to identify candidates for hemi-ablative focal therapy. BJU Int. 2016 Jan;117(1):48-54. doi: 10.1111/bju.13090. Epub 2015 May 11. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | the spatial distribution based on the biopsy tissue | to simulate the spatial distribution of cancer based on the biopsy tissue contained cancer with the help of TPS system | 2 years | |
Secondary | the spatial distribution based on the large tissue slice technique | to simulate the spatial distribution based on the large tissue slice technique after radical prostatectomy | 2 years |
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