Prostate Cancer Screening in Men With Germline BRCA2 Mutations

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the incidence of prostate cancer in men with the BRCa2 gene mutation as an independent indicator for prostate cancer screening.

Clinical Trial Description

This is a cohort screening study to prospectively identify the incidence of prostate cancer in a population of BRCA2 carriers. All men identified to have a BRCA2 mutation as part of the Yale Cancer Genetic Counseling Program will be approached and offered participation in the study via our program newsletter, BRCA listserv, Facebook page and a targeted mailing. Standard of care screening at the Yale Cancer Center for men with a normal prostate cancer risk consists of a PSA test and prostate physical examination beginning at age 50 years and if either is abnormal an MRI of the prostate followed by Fusion-targeted biopsy of the prostate is performed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02154672
Study type	Observational
Source	Yale University
Contact
Status	Completed
Phase
Start date	May 2014
Completion date	November 1, 2019

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