Prostate Cancer Clinical Trial
Official title:
Analysis of Biopsy Results at 36 Months After Permanent I-125 Implantation Therapy Plus LHRH-agonist Therapy for Patients With Untreated Intermediate Prostate Cancer.
RATIONALE: Studying samples of blood and tissue from patients with prostate cancer after
receiving implant radiation therapy and luteinizing hormone-releasing hormone agonist may
help doctors identify biomarkers related to cancer and help doctors predict how patients
will respond to treatment.
PURPOSE: This laboratory study is looking at PSA levels and biopsy samples after undergoing
implant radiation therapy and luteinizing hormone-releasing hormone agonist therapy in
patients with stage I or stage II prostate cancer.
OBJECTIVES:
- To analyze biopsy results at 36 months after permanent iodine I 125 implantation
therapy and luteinizing hormone-releasing hormone (LHRH) agonist therapy for patients
with untreated intermediate-risk prostate cancer.
OUTLINE: Patients received luteinizing hormone releasing-hormone (LHRH) agonist therapy and
permanent iodine I 125 implantation on protocol JUSMH-BRI-GU05-01.
Patients undergo blood sample collection and tissue biopsy for biomarker/laboratory analysis
at 36 months after receiving brachytherapy and releasing-hormone agonist therapy. PSA levels
and biopsy results are compared.
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