Prostate Cancer Clinical Trial
Official title:
A Randomised, Parallel-arm, Open-label Trial Comparing Degarelix With Goserelin Plus Anti-androgen Flare Protection (Bicalutamide), in Terms of Reduction in International Prostate Symptom Score (IPSS), in Patients With Lower Urinary Tract Symptoms (LUTS) Secondary to Locally Advanced Prostate Cancer
The purpose of this trial was to see how well a new trial drug (degarelix) worked on lower
urinary tract symptoms (also known as LUTS) in prostate cancer patients as compared to how a
standard drug hormonal treatment worked on the same symptoms. The advancement/worsening of
prostate cancer may be associated with LUTS and the symptoms may impact the ability to
urinate normally and thereby the quality of life for these patients.
Patients were randomly selected (like flipping a coin) to receive either degarelix or
standard hormone therapy (combination of goserelin and bicalutamide) for a 3 month treatment
period. During this period the relief of urinary symptoms was evaluated via a questionnaire
filled in by patients and addressing the severity and frequency of their symptoms.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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