Prostate Cancer Clinical Trial
Official title:
An Open-Label, Randomized, Multicentre Study to Evaluate the Efficacy of Two Zoledronic Acid Schedules on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy
The purpose of this study is to see if giving zoledronic acid three times a year is as
effective as five times a year, in increasing bone strength in men with prostate cancer. All
participants will receive the active drug but half will receive drug every 6 months and the
other half will receive drug every 3 months. Both patient and doctor will know which
treatment a patient is receiving.
After 1 year of treatment bone strength will be measured with scans and compared to the
strength at the start of the study. All participants will stop receiving the drug after 1
year and will be seen back in the clinic, annually for another 2 years for follow-up.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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