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Prognosis clinical trials

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NCT ID: NCT06467864 Recruiting - Clinical trials for Respiratory Tract Infections

Predicting Ventilator-associated Lower Respiratory Tract Infection Outcomes Using Sequenced-based Early Microbiological Response: A Multi-center Prospective Study

Start date: July 1, 2024
Phase:
Study type: Observational [Patient Registry]

We are using a tool called QtNGS to measure the abundance of local pathogens in patients with ventilator-associated lower respiratory tract infections. We hypothesize that changes in pathogen abundance before and after treatment are related to patient outcomes. This study aims to evaluate the effectiveness of the tool by analyzing the changes in pathogen abundance and exploring the relationship between these changes and clinical outcomes.

NCT ID: NCT06435728 Active, not recruiting - Prognosis Clinical Trials

Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI

Start date: March 1, 2024
Phase:
Study type: Observational

Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship between FFR and IMR and the prognosis of patients with acute myocardial infarction was analyzed

NCT ID: NCT06416501 Not yet recruiting - Colorectal Cancer Clinical Trials

The Impact of Colorectal Cancer Screening on Surgical Outcomes

Start date: May 11, 2024
Phase:
Study type: Observational

This study aims to investigate the pathological characteristics and surgical outcomes of stage III CRC patients detected through screening. Data extracted from the database included the following patient information: age at diagnosis, gender, tumor location, neoadjuvant therapy, surgical procedures, histologic type, differentiation, vascular invasion, perineural invasion, pathological T stage, pathological N stage, and survival outcomes.

NCT ID: NCT06409507 Completed - Clinical trials for Hepatocellular Carcinoma

Research and Application for New Clinical Diagnosis and Treatment System for HBV Related HCC Liver Transplantation

Start date: January 1, 2015
Phase:
Study type: Observational

The study evaluated the protein expression levels of FK506-binding protein 12 (FKBP12) in hepatocellular carcinoma (HCC) and paracancerous tissues using immunohistochemistry (IHC). This study aimed to determine the role of FKBP12 in the outcome of liver transplantation recipients with HCC, especially those exceeding the Milan criteria. In addition, we explored how sirolimus administration affected LT recipients'prognosis depending on different FKBP12 expression, aiming to provide some advice for clinical sirolimus application after LT.

NCT ID: NCT06172816 Recruiting - Covid-19 Clinical Trials

A Cohort Study on the Clinical Characteristics and Prognosis of HIV/AIDS Patients Infected With SARS-CoV-2

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

On February 11th, 2020, the International Classification of Viruses named the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as novel coronavirus (COVID-19, Covid-19 for short). At present, COVID-19 has become a global pandemic. However, the persistent replication of HIV in PLWH and the cellular immunodeficiency and persistent inflammation caused by it may have different effects on the susceptibility, severity and course of Covid-19. Several large cohort studies have found evidence of increased risk of hospitalization and death in patients with HIV and Covid-19 co-infection. Meanwhile, a meta-analysis of 22 studies shows that HIV infection is still an important risk factor for acquiring Covid-19 infection, and it is associated with a higher risk of death in COVID-19. In order to further clarify the clinical features and prognosis of HIV co-infection with Covid-19 and explore its immune mechanism, so we will carry out the study.

NCT ID: NCT06087887 Completed - Prognosis Clinical Trials

Association Between Tumor Size and Prognosis in Patients With Small Bowel adenocarcinoma-a SEER-based Study

Start date: January 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about in small bowel adenocarcinoma patients. The main question it aims to answer is the association between tumor size and prognosis in patients with small bowel adenocarcinoma. Participants will be compared for the relationship between tumor size and prognosis.

NCT ID: NCT06005883 Completed - Clinical trials for Hepatocellular Carcinoma

Surgical Outcome of HCC With Portal Vein Tumor Thrombosis on the Basis of Risk Scoring

Start date: April 10, 2021
Phase:
Study type: Observational

The goal of this multicenter retrospective cohort study is to investigate the clinical outcomes and prognostic factors after hepatic resection in patients with HCC exhibiting PVTT, and to develop a prognostic index that can be helpful in determining the treatment strategy.

NCT ID: NCT05848310 Recruiting - Prognosis Clinical Trials

Preoperative Serum FGF19 in the Prognosis of Biliary Atresia

Start date: October 15, 2023
Phase:
Study type: Observational

To investigate the role of preoperative serum FGF19 level in the prognosis of biliary atresia.

NCT ID: NCT05802667 Not yet recruiting - Inflammation Clinical Trials

A Cohort Study of Correlation Between Mast Cells and Prognosis in Patients With Acute Myocardial Infarction

Start date: April 1, 2023
Phase:
Study type: Observational

By including patients with acute myocardial infarction, mast cell markers were analyzed and the relationship between mast cells and patients with acute myocardial infarction was analyzed

NCT ID: NCT05744609 Completed - Pneumonia Clinical Trials

Predicting Severe Outcomes Among Children Hospitalized With Community-acquired Pneumonia

Start date: January 1, 2017
Phase:
Study type: Observational

In this study, investigators aimed to develop and validate a risk score to predict severe outcomes (e.g., mortality and ICU admission) in children who were admitted to the Children's Hospital of Fudan University between 2017 and 2022 due to community-acquired pneumonia (CAP). The objectives were as follows. 1. Develop a risk prediction model based on demographic, comorbidity, clinical characteristics, laboratory data, and chest radiographic reports to predict severe outcomes among children hospitalized with CAP; 2. Develop a risk scoring system and determine the cut-off point; 3. Externally validate the easy-to-use risk score.