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Problem Behavior clinical trials

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NCT ID: NCT02450240 Completed - Depression Clinical Trials

Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders

Start date: January 2015
Phase:
Study type: Observational

In this study the investigators will seek to improve our understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of mood, substance use, and eating behavior. The investigators will recruit 1000 individuals and use a wide range of assessment tools, neuroimaging measures, blood and microbiome collections and behavioral tasks to complete the baseline and follow-up study visits. Upon completion, the investigators aim to have robust and reliable dimensional measures that quantify these systems and a set of assessments that should be recommended as a clinical tool to enhance outcome prediction for the clinician and assist in determining who will likely benefit from what type of intervention.

NCT ID: NCT02423746 Completed - Hearing Loss Clinical Trials

Assessing and Addressing Behaviors in Children With Hearing Loss

Start date: April 2015
Phase: N/A
Study type: Interventional

Purpose: This study is a feasibility trial of an existing evidence-based behavioral parent training program with parents of preschool-aged children who were born deaf or hard of hearing (DHH). The hypotheses of this study are (a) that a randomized control trial of the Family Check Up with this population will be feasible, (b) parents will rate the intervention as acceptable, and (c) a signal of effect will be observable among intervention group parents compared to controls for the following outcome variables: child behaviors, parenting behaviors, and parenting sense of competence.

NCT ID: NCT02396576 Completed - Depression Clinical Trials

Using Telehealth to Deliver Mental Health Services in Primary Care Settings for Children in Underserved Areas

Start date: April 7, 2015
Phase: N/A
Study type: Interventional

In partnership with a multi-site, Los Angeles-area community clinic consortium, North East Valley Health Corporation (NEVHC), the investigators will use telehealth to integrate pediatric developmental, behavioral and mental health (DB/MH) services into primary care for low-income, publicly insured children. During Project Year 1, the investigators used qualitative methods to conduct and analyze interviews with parents, clinicians, and staff at NEVHC to assess their perspectives on the delivery of child DB/MH services and on a potential telehealth-based patient visit, coordination, and clinician education system for the provision of DB/MH specialty care in primary care settings to children ages 5-12. This data was used in a stakeholder-engaged process to customize a telehealth-based delivery system for pediatric DB/MH services that can be integrated into primary care settings. During Project Years 2-3, the investigators will conduct a cluster randomized controlled trial (RCT) to compare the customized telehealth-based patient visit, coordination, and clinician education system to the usual in-person, community- based referral system at NEVHC. This study will examine whether a telehealth developmental, behavioral and mental health delivery model can be an effective, efficient, and family-centered way to provide integrated DB/MH services to children in low-income communities.

NCT ID: NCT02334098 Completed - Aggression Clinical Trials

Omega-3 Supplementation and Behavior Problems

Start date: February 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The objectives of this project are as follows: 1. To assess whether omega-3 dietary supplementation for six months can reduce externalizing behavior problems (antisocial and aggressive behavior) in schoolchildren aged 8 to 18, both at the end of treatment and six months post-treatment 2. To assess whether omega-3 supplementation is more effective in children with more psychopathic-like traits.

NCT ID: NCT02305134 Completed - Clinical trials for Attention Deficit and Disruptive Behavior Disorders

Tipepidine in Children With Attention Deficit/Hyperactivity Disorder (AD/HD): a Double-blind, Placebo-controlled Trial

Start date: June 11, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Tipepidine (3-[di-2-thienylmethylene]-1-methylpiperidine) has been used solely as a nonnarcotic antitussive in Japan since 1959. The safety of tipepidine in children and adults has already been established. It is reported that tipepidine inhibits G-protein-coupled inwardly rectifying potassium (GIRK)-channel currents. The inhibition of GIRK channels by tipepidine is expected to modulate the level of monoamines in the brain. We put forward the hypothesis that tipepidine can improve attention deficit/hyperactivity disorder (ADHD) symptoms by modulating monoaminergic neurotransmission through the inhibition of GIRK channels. The purpose of this double-blind, placebo-controlled trial is to confirm whether treatment with tipepidine can improve symptoms in pediatric patients with ADHD.

NCT ID: NCT02250339 Completed - ADHD Clinical Trials

A Prospective Observational Study of Family-based Interventions for Children With Neuropsychiatric and/or Psychiatric Disorders

Start date: December 2013
Phase:
Study type: Observational

The purpose of this study is to examine the feasibility and the effects of family-based interventions for children (aged 5-12) with neuropsychiatric and psychiatric disorders in Finnish health care settings.

NCT ID: NCT02247986 Withdrawn - Conduct Disorder Clinical Trials

Investigating the Impact of Methylphenidate on Neural Response in Disruptive Behavioral Disorder

Start date: September 4, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Background: - Disruptive behavior is a common problem for children and adolescents. It can be treated with some success with stimulant medicine. Researchers want to learn more about how this works. Objective: - To learn how the brain changes when taking the medicine methylphenidate for behavior problems. Eligibility: - Children ages 10 17 with conduct disorder and/or attention deficit disorder. - Healthy volunteers the same age. Design: - Participants will be screened under a separate protocol. - Participants will have two 3-hour sessions at the clinic. Girls who are menstruating will have a pregnancy test before their scans. - Visit 1: All participants will: - Perform simple tests on a computer. - Fill out a questionnaire along with their parent or guardian. - Have an MRI scan. A magnetic field and radio waves take pictures of the brain. Participants will lie on a table that slides into a metal cylinder. A coil will be placed over their head. They will be in the scanner for 60 minutes, lying still or performing a simple task. They will practice the task before the scan. A computer screen will show them task information during the scan. The scanner makes loud knocking sounds. Participants will get earplugs. Their parent or guardian can stay with them during the scan. - Only participants with behavior disorders will: - Take a pill of the study medicine or placebo. - Be monitored for any side effects. - Visit 2 is a repeat of Visit 1, except participants who got a pill in Visit 1 will get the other pill in Visit 2. For healthy volunteers, the 2 visits are exactly the same.

NCT ID: NCT02229305 Completed - Depression Clinical Trials

Maine Implementation Study - Phase III

Start date: December 2008
Phase: N/A
Study type: Interventional

This study focused on youths who were referred to community-based mental healths clinics for problems related to disruptive behaviors, depression, anxiety, traumatic stress, and any combination of these problems. Therapists were randomly assigned to deliver usual treatment procedures (usual care, or UC) in their clinics or an evidence-based, modularized treatment (Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems, or MATCH-ADTC). Assessments were conducted at pre-treatment and post-treatment, and every 3 to 6 months for two years. Results will address critical questions about deployment of evidence-based youth practices to clinical settings.

NCT ID: NCT02191956 Completed - Clinical trials for Disruptive Behavior Disorders

Technology to Enhance Treatment for Early Conduct Problems in Low Income Families

TE-HNC
Start date: April 2013
Phase: N/A
Study type: Interventional

This study aims to the test the efficacy and cost effectiveness of new service delivery methods to enhance the reach and impact of the standard of care treatment, Behavioral Parent Training (BPT), for early onset disruptive behavior disorders.

NCT ID: NCT02165371 Completed - Clinical trials for Child Behaviour Problems

The Sinovuyo Caring Families Project: a Randomized Controlled Trial of a Parenting Programme

Start date: February 2014
Phase: N/A
Study type: Interventional

It has been established that children in families affected by either intimate partner violence or Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) are at substantially increased risk of poor parenting and child maltreatment. In the sub-Saharan African context of high levels of HIV/AIDS and family violence, it is crucial that parents be supported to establish positive parenting practices and reduce harsh or abusive parenting within their families.This randomized controlled trial will be testing the Sinovuyo Caring Families Program (n = 296), a 12-session (2.5 hour per session) parenting intervention for primary caregivers of children between 2 and 9 years old. Participants will not be restricted to biological parents and include primary caregivers of children between 2 and 9 years old, who live in the same house as the child at least 4 nights per week. Participants will be recruited through systematic household sampling, liaising with Western Cape Department of Social Development and local community-based NGOs. Self-reporting questionnaires and qualitative observational assessment data for intervention and control groups will be collected at pre- and post-test evaluation as well as 12-month follow-up. Primary outcomes will include child behaviour problems, harsh and inconsistent parenting and positive parenting. Secondary outcomes will include parental depression, parental stress, parental monitoring and supervision and parent perceived social support.