Neurophysiologic Correlates of Hypersomnia

Status Completed

Clinical Trial Summary

The goal of this project is to examine the neurophysiology of hypersomnia during sleep and wakefulness, to identify biomarkers for excessive sleepiness in neuropsychiatric disorders, and pilot acoustical slow wave induction during sleep in patients with hypersomnolence, to determine if this decreases daytime sleepiness in these patients. The primary study hypotheses are that individuals with hypersomnolence will have reduced slow wave activity (SWA) during sleep and increased waking theta/alpha activity during wake in specific brain regions. A secondary hypothesis is that acoustical slow wave induction in hypersomnolent patients will increase SWA during sleep, reduce theta/alpha activity during wake, and improve subjective sleepiness.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Bipolar Disorder
Depression
Depressive Disorder
Depressive Disorder, Major
Disease
Disorders of Excessive Somnolence
Major Depressive Disorder
Narcolepsy
Primary Hypersomnia
Primary Insomnia
Sleep Initiation and Maintenance Disorders

Clinical Trial Details

NCT number	NCT01719315
Study type	Observational
Source	University of Wisconsin, Madison
Contact
Status	Completed
Phase
Start date	November 2012
Completion date	June 2018

View Details

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