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Pregnancy clinical trials

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NCT ID: NCT02555332 Completed - Pregnancy Clinical Trials

Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus

Start date: December 2012
Phase: N/A
Study type: Observational

This study was conducted to analyze the role of TSH level and TPOAb status in early pregnancy and use this information in assessment of the risk of gestational diabetes mellitus at different weeks of gestation when the FT4 level is normal.

NCT ID: NCT02554409 Completed - Pregnancy Clinical Trials

Sanofi Pasteur Quadrivalent Intradermal Influenza Vaccine Pregnancy Registry

Start date: October 13, 2015
Phase:
Study type: Observational

The Sanofi Pasteur Fluzone Intradermal Quadrivalent vaccine (Fluzone QIV-ID) Pregnancy Registry will be a prospectively recruited pregnancy surveillance program designed to collect to collect and analyze information on vaccine exposures, pregnancy outcomes, and fetal and offspring outcomes on pregnant women exposed to Fluzone QIV-ID vaccine.

NCT ID: NCT02550444 Completed - Pregnancy Clinical Trials

Intrathecal Clonidine in Cesarean Section May Lead to Worse Blood Gas Results in the Newborns

Start date: April 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate effects of intravenous clonidine in acute and chronic post-cesarean pain, possible adverse effects over mother-newborn pair, in comparison to intrathecal adjuvant clonidine and placebo.

NCT ID: NCT02542488 Completed - Pregnancy Clinical Trials

STOPBANG As A Screening Tool for Obstructive Sleep Apnoea in Pregnancy

Start date: February 2, 2016
Phase:
Study type: Observational

This study evaluates the use of the STOPBANG questionnaire to predict whether a pregnant woman with class III obesity has obstructive sleep apnoea. All participants will have a STOPBANG score and modified STOPBANG score (substituting Epworth score > 10 with the tired item) calculated and then be tested with overnight pulse oximetry to see if they meet ODI criteria for obstructive sleep apnoea.

NCT ID: NCT02536612 Completed - HIV Clinical Trials

Empower, Nudge: Increasing Dual Protection in South Africa

EN
Start date: May 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to test feasibility and acceptability of a lottery to help women in Cape Town, South Africa to continue using long-acting reversible contraceptives to avoid unintended pregnancies, and to also use condoms to reduce sexually transmitted infections including HIV.

NCT ID: NCT02534051 Completed - Obesity Clinical Trials

A Clinical Care Pathway for Obese Pregnant Women: A Pilot Cluster RCT

Start date: October 2015
Phase: N/A
Study type: Interventional

Clinics will be randomized to the use of the care pathway for obese pregnant women or standard care. Women who are (1) up to 20 weeks + 6 days gestation into their pregnancy, (2) are carrying one baby (not twins) that is healthy (no life threatening anomalies) and (3) have a Body Mass Index ≥ 30 kg/m², will be included. Data will be obtained from the Ministry of Health's Antenatal Records, charts, and for those in the intervention group, the care path (filled out by the practitioners - the participants' obstetrician, midwife, or family doctor). At the end of the study, practitioners will complete a survey, participate in structured interviews to understand barriers, facilitators, and motivators of using the care path. Primary Objective: To evaluate the feasibility of implementing and testing a clinical care pathway for obese pregnant women in a pilot cluster randomized controlled trial (RCT) Secondary Objectives: To obtain pilot data on A) process outcomes (steps of the pathway, e.g. what % of obese women receive a screen for diabetes) B) clinical outcomes (e.g. what % of obese women receive a diagnosis of diabetes), C) provider outcomes (e.g. Is the intervention acceptable, feasible & efficient? Barriers & facilitators to use, effectiveness? [Structured interviews])

NCT ID: NCT02528136 Completed - Pregnancy Clinical Trials

The Clinical Carbetocin Myocardium Trial

CMT
Start date: September 2015
Phase: Phase 4
Study type: Interventional

Randomized comparison of different cardiotoxicity of carbetocin and oxytocin.

NCT ID: NCT02527018 Completed - Hypertension Clinical Trials

A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women

Start date: November 2014
Phase: N/A
Study type: Observational

Primary Endpoint: Quantify the hemodynamic changes in preeclampsia using the non-invasive Nexfin device. Secondary Endpoint: Determine if measurable hemodynamic changes are statistically correlated with B-type natriuretic peptide (BNP) levels.

NCT ID: NCT02526459 Completed - Pregnancy Clinical Trials

The Effect of Birth Plans on Obstetrical Outcomes

Start date: October 2015
Phase: N/A
Study type: Interventional

The study design is a prospective, single institution, randomized control trial in which the introduction of a birth plan is the intervention and a comparison of the rate of Caesarean sections between participants in the control group (no birth plan) and the experimental group (birth plan) is the primary outcome.

NCT ID: NCT02523755 Completed - Pregnancy Clinical Trials

Evaluation of Regional Distribution of Ventilation During Labor With or Without Epidural Analgesia

Start date: September 2015
Phase: Phase 4
Study type: Interventional

With an efficient epidural analgesia the physiological effects of pain are disabled during labor. Pain may cause an increase of minute volume, oxygen consumption and a decrease of paCO2 (Arterial CO2 pressure). The study will evaluate the lung function before and after labor with and without epidural analgesia. With more efficient breathing, the occurence of atelectasis should be reduced; this effect will be investigated in these settings for the first time with the electrical impedance tomography, which is a completely non-invasive measure.