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Pregnancy clinical trials

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NCT ID: NCT02696694 Completed - Pregnancy Clinical Trials

Predictive Value of Mid-luteal Serum Progesterone Levels in Egg Donation Cycles

Start date: February 2016
Phase: N/A
Study type: Observational

This study aims to investigate the impact of serum progesterone concentrations on the day of embryo transfer in egg donation cycles under hormonal replacement therapy. As secondary outcomes, the investigators will investigate if endometrial volume measured by three-dimensional (3D) ultrasound on the day of embryo transfer is related with progesterone levels and with chances of pregnancy.

NCT ID: NCT02695563 Completed - Pregnancy Clinical Trials

Effects of Vaginal Lactoferrin Administration Prior to Genetic Amniocentesis on Inflammatory Mediators

Start date: January 2014
Phase: Phase 2
Study type: Interventional

The aim of the study is to evaluate the effect of vaginal lactoferrin administration on amniotic fluid PGE2 level and MMP-TIMP system in women undergoing genetic amniocentesis. Two groups of patients will be prospectively enrolled: not treated with lactoferrin and treated with vaginal lactoferrin 4 hours prior to mid-trimester genetic amniocentesis.

NCT ID: NCT02694107 Completed - Pregnancy Clinical Trials

Effectiveness of Proprioceptive Training on Dynamic Postural Balance During Pregnancy

Start date: July 2015
Phase: N/A
Study type: Interventional

The purpose of the present study was to measure the effect of proprioceptive training, short-term, on dynamic postural balance during pregnancy and after 8 weeks of follow-up. Thirty-nine pregnant women were randomized to either the intervention group(n=20) , which would perform proprioceptive exercise, or the control group(n=19, no intervention) .

NCT ID: NCT02693028 Completed - Pregnancy Clinical Trials

Lactobacillus Reuteri Feasibility Study on Probiotic Treatment and Perinatal Microbiome

Start date: November 2015
Phase: N/A
Study type: Interventional

Investigators want to investigate if the Lactobacillus Reuteri (probiotic bacteria) given to pregnant women can be found in different maternal compartments and in the first stool and oral swab collected immediately after birth of a newborn delivered by cesarean delivery. Investigators also want to explore if exposure to this Lactobacillus Reuteri alters the level of inflammation in different compartments of the mother and the infant.

NCT ID: NCT02692404 Completed - Pain Clinical Trials

Labor Pain and Postpartum Behavioral Health Outcomes Study

LPPD
Start date: January 2016
Phase:
Study type: Observational

In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric and pain characteristics until 3 months postpartum. The primary outcome is postpartum depression, assessed by Edinburgh Postnatal Depression Scale (EPDS). Infants will also be observed for infant development characteristics over time. Women who choose to receive labor epidural analgesia will be observed, as well as women who choose to avoid labor epidural analgesia. At baseline, women will complete baseline surveys as well as a baseline pain sensitivity test (quantitative sensory testing, QST). During labor, they will complete an electronic pain diary delivered by a bedside mobile device. Three postpartum assessments will occur over 3 months to assess maternal depression, other psychosocial variables, and infant development.

NCT ID: NCT02683005 Completed - Pregnancy Clinical Trials

Study of Hepatitis C Treatment During Pregnancy

HIP
Start date: September 2016
Phase: Phase 1
Study type: Interventional

Sofosbuvir and ledipasvir (LDV/SOF) are new directly acting antiviral drugs for the treatment of hepatitis C (HCV) that are highly effective, orally administered, well tolerated and preclinical evaluations in animal models indicate safe administration during pregnancy. This project will evaluate the safety and pharmacokinetics of antenatal LDV/SOF treatment for 12 weeks during the second and third trimester. If proven to be effective, antenatal treatment of HCV with LDV/SOF will prevent maternal HCV-related liver disease, perinatal transmission of HCV, and community transmission of HCV.

NCT ID: NCT02677558 Completed - Obesity Clinical Trials

The Impact of Obesity on Cardiac Function in Pregnancy

CFOP
Start date: January 2016
Phase:
Study type: Observational

The purpose of this study is to determine the impact of obesity in pregnancy on maternal cardiac function. For this, morbidly obese term pregnant women (study group) and term pregnant women of normal weight are assessed by transthoracic echocardiography.

NCT ID: NCT02676882 Completed - Pregnancy Clinical Trials

EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy

Start date: January 24, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy, or treating women who are currently in a depressive episode while pregnant or planning pregnancy.

NCT ID: NCT02675179 Completed - Pregnancy Clinical Trials

EOS® Versus Spiral CT Technique for Achieving a Pelvimetry in Suites of Obstructed Labor.

PELVI-EOS
Start date: May 27, 2016
Phase: N/A
Study type: Interventional

The aim of this study is to demonstrate in vivo the concordance of the imagery system EOS and the spiral CT in women having had an obstructed delivery. If this concordance is demonstrated, it would allow the use of this new technique of imagery, to realize a pelvimetry during the pregnancy less irradiating for the mother, and the fetus.

NCT ID: NCT02674022 Completed - Pregnancy Clinical Trials

Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children

Start date: January 20, 2016
Phase: N/A
Study type: Interventional

The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.