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Pregnancy clinical trials

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NCT ID: NCT00065897 Completed - Pregnancy Clinical Trials

Prenatal Testing: Amniocentesis Versus Transabdominal Chorionic Villus Sampling (TA CVS)

Start date: September 1996
Phase: N/A
Study type: Interventional

Prenatal diagnosis can provide information to parents about specific fetal disorders. However, invasive prenatal diagnostic procedures are associated with risks to the fetus. This study will compare the safety and effectiveness of two methods of invasive prenatal diagnosis: amniocentesis and transabdominal chorionic villus sampling (TA CVS).

NCT ID: NCT00065858 Completed - Pregnancy Clinical Trials

Effectiveness of BufferGel as a Vaginal Contraceptive

Start date: September 2001
Phase: Phase 2/Phase 3
Study type: Interventional

BufferGel is a new contraceptive gel designed to be used with a diaphragm. In addition to preventing pregnancy, BufferGel may also prevent some types of sexually transmitted diseases (STDs). This study will compare BufferGel to Gynol II, a currently available contraceptive gel.

NCT ID: NCT00065078 Active, not recruiting - Pregnancy Clinical Trials

Providing Birth Control Through Home Health Visits

Start date: June 2003
Phase: N/A
Study type: Interventional

This study will evaluate a program that provides birth control to low income and minority women through home visits by a community health nurse. The goal of the program is to reduce unwanted pregnancies.

NCT ID: NCT00060463 Active, not recruiting - Pregnancy Clinical Trials

Increased Access to Emergency Contraceptive Pills

Start date: October 2002
Phase: N/A
Study type: Interventional

This study will evaluate the effect of easy access to emergency contraceptive pills (ECPs) on the rates of pregnancy and sexually transmitted infections (STIs).

NCT ID: NCT00059540 Completed - Pregnancy Clinical Trials

The Maternal Lifestyle Study (MLS)

MLS
Start date: May 1993
Phase: Phase 4
Study type: Observational

This is a longitudinal, multi-site observational study of the long-term effects of a mother's use of cocaine and/or opiates during pregnancy on her infant. This observational study evaluates the medical, developmental, social, environmental, and neurobehavioral outcomes for 1,400 of the original cohort of children. A series of follow-up examinations of these children were conducted in 5 phases: 1-36 months, 3.5-7 years, and 8-11 years. Children are currently being examined at 13 years of age.

NCT ID: NCT00044603 Completed - Pregnancy Clinical Trials

Vulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.

Start date: February 2000
Phase: N/A
Study type: Observational

The goal of this study is to examine the effects of in utero and postnatal exposure to environmental pollutants in a cohort of pregnant women and their newborns in Krakow, Poland

NCT ID: NCT00041964 Completed - HIV Infections Clinical Trials

A Study of HIV Levels During Pregnancy and After Childbirth

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this study is to find out if HIV-infected pregnant women taking anti-HIV drugs have an increased amount of HIV in their blood (viral load) after having the baby. The purpose of A5153s, a substudy of A5150, is to characterize two anti-HIV drugs (nelfinavir [NFV] and lopinavir/ritonavir [LPV/r]) in HIV-infected women during pregnancy and after childbirth. Sometimes pregnant women have an increase in their HIV viral load after their baby is born. This study will try to find out how often this happens. It will also examine possible reasons why the increase in viral load occurs.

NCT ID: NCT00028145 Completed - HIV Infections Clinical Trials

Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission

Start date: October 2002
Phase: N/A
Study type: Observational

The purpose of this study is to collect and study clinical and laboratory information about a pregnant or new mother and her medical care that will increase our knowledge of the best care for HIV-infected pregnant women and their children. The rate of transmission of HIV from mothers to their infants has gone down. Specific U.S. Public Health Service guidelines recommend that HIV-infected pregnant women be treated with anti-HIV therapies; but the effectiveness of treatment and safety for the mother and her infant have not been fully examined. This study will monitor the health of women and their infants while they receive anti-HIV therapy. Also, this study will provide information that may be used for future studies.

NCT ID: NCT00017797 Completed - HIV Infections Clinical Trials

Problems Associated With the Use of Anti-HIV Drugs in HIV-Infected Pregnant Women

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this study is to find out if HIV-infected pregnant women who take protease inhibitors (PIs) are more likely to have blood sugar problems than those who do not take PIs. HIV-infected people generally are treated with a combination of different types of anti-HIV drugs, 1 of which is usually a PI. The same holds true for pregnant women, but not much is known about the use of these drugs in pregnancy. Blood sugar and liver problems caused by anti-HIV drugs in nonpregnant patients are well known but their effects in pregnancy are not. Also, certain physical changes brought about by pregnancy may affect the way drugs are handled in the body. There remains a need for further study into the use of anti-HIV drugs during pregnancy and their effect on the safety of the mother and baby.

NCT ID: NCT00017719 Completed - HIV Infections Clinical Trials

Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy

Start date: May 2002
Phase: Phase 3
Study type: Interventional

The best anti-HIV treatment regimen for pregnant women is not known. Protease inhibitors (PIs) are often used, but they have side effects that may be harmful for pregnant women. It is not known if treatment regimens that do not include PIs are as effective in pregnant women as those that include PIs. This trial will compare two anti-HIV treatment plans, one with and one without PIs, in women who start HIV treatment during pregnancy. The study will evaluate the effects of the anti-HIV drugs on the developing infant and prevention of mother-to-child HIV transmission during pregnancy.