Iodine Supplement Strategies Between Routine Iodine Supplementation and Selective Iodine Supplementation

Pregnancy Related Clinical Trial

Official title:

The Study to Compare Iodine Supplement Strategies Between Routine Iodine Supplementation and Selective Iodine Supplementation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03078140
• Other study ID #: 4298
• Status: Completed
• Phase: N/A
• Start date: May 1, 2017
• Est. completion date: May 31, 2018

Study information

• Verified date: October 2018
• Source: ChaingMai University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Pregnant women who attend at our antenatal clinic will random to 2 groups. First will receive routine iodine supplementation. The other will receive iodinated pill or only iron supplementation base on their urine iodine status.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 208
• Est. completion date: May 31, 2018
• Est. primary completion date: April 30, 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• first visit for antenatal care in the first trimester

• singleton pregnancy

• delivered at Maharaj Nakorn Chiangmai Hospital

Exclusion Criteria:

• thyroid disease which diagnosed before pregnancy or currently

• history of thyroid gland surgery or iodine ablation therapy

• received iodine supplement before pregnancy

• received any medication for thyroid disease treatment, within 6 weeks postpartum women or breast feeding period

• family history of thyroid disease

• having underlying disease or contraindication which cannot received iodine supplement

• loss follow-up or incomplete data.

Related Conditions & MeSH terms

• Iodine Deficiency
• Pregnancy Related

Intervention

Dietary Supplement:
• Triferdine
Triferdine 1 tablet daily Start from 14 weeks of gestation until delivery
• Triferdine/Ferli-6
For the participants assigned to this group, urine iodine level will be checked first. For participants with normal urine iodine level, Ferli-6 1 tab daily will be given. For those with low urine iodine level, Triferdine 1 tab daily will be given. Medication will be started from 14 weeks of gestation until delivery.

Locations

Country	Name	City	State
Thailand	Kuntharee Traisrisilp	Chiang Mai

Sponsors (1)

Lead Sponsor	Collaborator
ChaingMai University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	iodine status	mean urine iodine	at delivery