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Pregnancy Related clinical trials

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NCT ID: NCT05253742 Not yet recruiting - Pregnancy Related Clinical Trials

Fetal MRI Acquisition and Sequence Development

FMASD
Start date: May 31, 2023
Phase:
Study type: Observational

Testing of new magnetic resonance imaging (MRI) pulse sequences (image acquisition software) for imaging the fetus to improve workflow and image quality in fetal imaging and diagnosis. The investigators would like to develop novel MRI approaches to enhance fetal imaging with MRI, in the presence of motion. As part of technical development, the investigators plan to develop methods to improve structural T1 and T2 weighted images, MR angiography, diffusion and spectroscopy measurements of the fetus.

NCT ID: NCT05144893 Not yet recruiting - Pregnancy Related Clinical Trials

Brief Virtual Mindfulness-based Group Intervention With Social Support for Perinatal Individuals

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

This is a feasibility and acceptability study for 4- week virtual mindfulness-based intervention with social support for perinatal individuals at higher risk for substance use. This study builds on the longitudinal collection of questionnaire data from pregnant and postpartum people during the COVID-19 pandemic. Each closed virtual support group will meet weekly for 4 weeks using a video conference platform. Groups will be focused on grounding, thinking patterns, self-compassion and self-care. This approach will foster increase awareness of wellbeing as well as social support between group participants. Primary outcomes include the feasibility and acceptability of this group-based intervention for perinatal individuals.

NCT ID: NCT05080569 Not yet recruiting - Pregnancy Related Clinical Trials

Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment

LUMO
Start date: December 2022
Phase: Phase 4
Study type: Interventional

The LUMO study is a multicenter, randomized controlled trial that evaluates the effectivity of luteal phase support in MOH/IUI treatment.

NCT ID: NCT05080309 Not yet recruiting - Pregnancy Related Clinical Trials

Effect of Oral Carbohydrate Intake > 44kCal Per Hour During Labour on the Rate of Instrumental Vaginal Delivery

soliso-2
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Carbohydrate intake during physical exercise improves muscle performance and decreases fatigue. We hypothesized that carbohydrate intake during labor which is a period of significant physical activity can decrease the instrumental vaginal delivery rate. Following Siliso study we found a trend toward a decrease in instrumental vaginal delivery and the mount of carbohydrate intake durong labour. However due to some limitations no clear conclusion could be drawn. The present study is designed to examine the relationship between a high calory oral intake (>44 kCal/hour during labour) and the rate of instrumental delivery.

NCT ID: NCT04999670 Not yet recruiting - Pregnancy Related Clinical Trials

Fascial Closure and Post-caesarean Pain

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This study will evaluate post-operative pain in patients undergoing elective caesarean sections based on the method of fascial closure. Patients will be randomised into one of three groups based upon the method of fascial closure and will be followed up over a 10 week period evaluating analgesia use in the acute setting, and also following up with pain scores using a visual analogue score throughout the follow-up period.

NCT ID: NCT04960800 Not yet recruiting - Pregnancy Related Clinical Trials

Effect of a Specific Exercise Program During Pregnancy on Diastasis Recti Abdominis

Start date: September 2021
Phase: N/A
Study type: Interventional

Diastasis Rectus abdominis is a common condition in pregnant and postpartum women, where the connective tissue between the two muscle bellies of the rectus abdominis muscle is stretched and weakened, causing an increased inter-rectus distance. Treatment of this condition aim to reduce the inter-rectus distance, and conservative treatment including therapeutic exercise is the primary treatment of choice. To date, there is no generally accepted protocol of therapeutic exercises for this condition, and the evidence as to which exercise modality is the most effective and feasible in reducing the inter-rectus distance in women presenting with diastasis rectus abdominis is both sparse and weak. As this condition occur during the last two trimesters of pregnancy and as there is a paucity of high-quality studies on a pregnant population, investigators will conduct a randomized controlled trial on the effect of a specific exercise program during pregnancy on diastasis rectus abdominis. 100 pregnant women in gestation week 25 presenting with diastasis rectus abdominis of ≥ 28 mm will be included. Participants will be allocated to either an intervention group or a control group by block randomization. The intervention group will participate in a 12-week specific exercise program, consisting of two group sessions and two self-managed sessions weekly. The control group will not participate in any exercise intervention; however, participants will be recommended to follow national guidelines for general exercise during pregnancy. Participants will be assessed prior to intervention, post intervention at gestation week 37, and 6 weeks, 6 and 12 months postpartum. The primary outcome measure will be change in the inter-rectus distance in mm, measured by two-dimensional ultrasonography.

NCT ID: NCT04773574 Not yet recruiting - Pregnancy Related Clinical Trials

Physiologic Ocular Changes During Pregnancy in Women With High Myopia.

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The prevalence of myopia is seemingly increasing, and it is one of the major causes of blindness. High myopia is defined as a refractive error with spherical equivalent exceeding -6 diopters and/or the axial length longer than 26.5 mm. The global prevalence of high myopia is estimated to rise from 2.7% of the world population in 2010 to 9.8% of the world population in 2050. High myopia is characterized by axial length elongation, and consequent stretching of the posterior eye wall (thin retina and choroid). There are many complications of high myopia such as posterior staphyloma, lacquer cracks and myopic choroidal neovascularization. Normal labour may cause the ocular complication in pregnant women with high myopia, such as macular hemorrhage. Therefore, the caesarean section with epidural anesthesia is recommended. Moreover, there is no standard screening guideline for pregnant women with high myopia.

NCT ID: NCT04693572 Not yet recruiting - Anesthesia Clinical Trials

Anesthetic Considerations for Repeat Cesarean Section - a Prospective Study

Start date: January 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to examine the anesthetic considerations and outcomes during repeated caesarean section and to compare such considerations in low-order vs high-order repeated caesarean sections.

NCT ID: NCT04686240 Not yet recruiting - Pregnancy Related Clinical Trials

Doppler Ultrasonographic Assessment of Fetal Internal Thoracic Artery Indexes

Start date: January 2021
Phase:
Study type: Observational

The aim of this study is to assess the feasibility of visualizing the internal thoracic artery (ITA), establishing the normogram for ITA pulsatility index (PI), resistance index (RI) and acceleration/ejection time (AT/ET) at 24-32 weeks.

NCT ID: NCT04682002 Not yet recruiting - Low Back Pain Clinical Trials

Low-back Pain During Pregnancy and Its Psycho-social Implications

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

Pregnancy-related pelvic girdle pain (PPP) and pregnancy-related lumbar pain (PLBP) are two distinct symptoms, which can occur together as lumbar-pelvic pain.The primary objective is to measure the impact of osteopathic manipulative treatment on pregnancy-related lumbar and pelvic pain. The secondary objective is to study the interaction between pain and psycho-social factors during the gestational period.