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Preeclampsia clinical trials

View clinical trials related to Preeclampsia.

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NCT ID: NCT05221164 Recruiting - Preeclampsia Clinical Trials

162 mg of Aspirin for Prevention of Preeclampsia

Start date: July 6, 2021
Phase: Phase 4
Study type: Interventional

This is a study to assess if 162 mg of aspirin will decrease rates of preeclampsia in pregnant patients compared to 81 mg of aspirin.

NCT ID: NCT05155852 Completed - Preeclampsia Clinical Trials

Bedside Monitoring to Identify Impaired Cerebral Autoregulation in Women With Postpartum Hypertension

Start date: August 13, 2021
Phase:
Study type: Observational

The purpose of this research study is to develop a protocol for NIRS-based bedside monitoring to identify impaired cerebral autoregulation in women admitted to the high-risk obstetrics unit with postpartum hypertension. The investigators will then pilot this protocol in 10 patients with high-risk neurological features, such as headache.

NCT ID: NCT05143710 Completed - Preeclampsia Clinical Trials

The Clinical and Prognostic Features of PRES

Start date: October 1, 2020
Phase:
Study type: Observational

The purpose of this study is to determine the features of clinical imaging, disease severity and pregnancy outcomes in posterior reversible encephalopathy syndrome with preeclampsia or eclampsia.

NCT ID: NCT05134285 Not yet recruiting - Hypertension Clinical Trials

Effects of Recurrent PE on Women and Offspring

RPOH
Start date: January 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to evaluate the risk factors of recurrent preeclampsia and compare the short-term and long-term adverse outcomes of women and their offspring.

NCT ID: NCT05131282 Not yet recruiting - Preeclampsia Clinical Trials

Maternal Serum Markers Predicting Preeclampsia at Early Gestations

Start date: May 2022
Phase:
Study type: Observational

The investigators aim to evaluate a blood test that can identify women at high-risk of PE at the 1st or early 2nd trimester.

NCT ID: NCT05124327 Completed - Preeclampsia Clinical Trials

Remote Monitoring and Follow-up for Postpartum Hypertensive Disorders of Pregnancy

Start date: March 7, 2022
Phase: N/A
Study type: Interventional

The literature unequivocally supports follow-up in the postpartum period post hospital discharge in hypertensive patients, compared to uncomplicated delivery follow-up recommendations of 4-6 weeks postpartum, leading to decreased morbidity and mortality, utilizing at-home blood pressure monitoring and virtual/telemedicine appointments. There is much evidence that telemedicine visits are equally, if not more effective, result in cost savings, and are generally preferred by patients, specifically when there is a risk of exposure for the patient and newborn, an appropriate factor to consider amidst the global Covid-19 pandemic. Maternal health and well-being have substantial links with cultural and racial factors. Black women are three times as likely to have morbid outcomes related to gestational complications, specifically hypertensive disorders of pregnancy. Minority populations have historically displayed inferior access to care due to concerns related to transportation, healthcare insurance, or provider accessibility and distrust, resulting in diminished compliance with follow-up and negative health sequelae. Telemedicine follow-up within 10 days of delivery (48-72 hours after discharge) reduces readmission rates, increase access to- and compliance with care, and improve patient safety satisfaction, thus establishing feasibility. Home vital sign monitoring gives an increased volume of data points for providers to utilize in titrating antihypertensive medications to optimize blood pressure control, ultimately decreasing stroke and cardiovascular risk. Existing research lacks comprehension regarding specific cardiological impacts of labile postpartum blood pressures, however researchers inferentially hypothesize that poor blood pressure management in the postpartum period can have devastating long-term cardiological consequences. This QI project will demonstrate standardized programming for patients with hypertensive disorders of pregnancy (HDP), which may potentially lead to increased compliance, satisfaction, and accessibility, resulting in improved long-term cardiovascular health in vulnerable populations. The American heart Association (AHA) and ACOG have established that HDP are associated with long-term cardiovascular disease, however obstetricians lack guidance on effective, evidence-based research for standardization of care, leading to subsequently disjointed medical management with much room for error in transitioning from obstetrician to internist or cardiologist. Thus, implementing and establishing feasibility of remote monitoring and follow-up while applying standardized algorithms and protocols for antihypertensive medication titration and management may provide support in addressing and eradicating these gaps. As such, this pilot project has massive prospective future applicability and benefit for a highly vulnerable population.

NCT ID: NCT05123560 Not yet recruiting - Preeclampsia Clinical Trials

Women's Perspective on First-trimester Preeclampsia Screening

Start date: April 1, 2022
Phase:
Study type: Observational

The aim of this study is to evaluate women's perception on first-trimester preeclampsia screening as it is performed currently in daily practice. Thus, the investigators will assess the degree of satisfaction regarding the information received previously to the date of screening, and on the same day the screening is performed (at the time of first-trimester scan). Women's unsderstanding regarding preeclampsia screening will be evaluated by means of an anonymous online questionnaire. Anxiety and stress related to the results will also be assessed.

NCT ID: NCT05056701 Recruiting - Preeclampsia Clinical Trials

Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care

PRECEDE
Start date: August 5, 2021
Phase: N/A
Study type: Interventional

Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric patient. These symptoms normally resolve within 2-3 months after delivery regardless of the severity of the pre-eclampsia. Regardless of its definition, preeclampsia is associated with an increased risk of obstetric events and, for the mother, an increased risk of developing chronic kidney disease (CKD), hypertension, diabetes and cardiovascular disease in the broad sense. The relationship between preeclampsia and Chronic Kidney Disease is, however, complex and not fully understood. Investigator proposes an interventional study to identify the diagnosis of Chronic Kidney Disease in patients who have developed an episode of Preeclampsia.

NCT ID: NCT05021692 Recruiting - Preeclampsia Clinical Trials

Efficiency of the Web-Based Support Program Based on the Health Promotion Model in Pregnant Women With Preeclampsia

preeclampsia
Start date: March 25, 2021
Phase: N/A
Study type: Interventional

In the literature, it has been reported that health promotion model-based care approaches are beneficial in gaining positive healthy lifestyle behaviors, taking responsibility for the individual's health and increasing the quality of life. It is thought that the health promotion model in pregnant women with preeclampsia will positively affect the healthy lifestyle behaviors and self-efficacy level of pregnant women by ensuring active participation of pregnant women in symptom management, reduce the stress of the pregnant and positively affect maternal and fetal-neonatal health outcomes. In line with this information, it was aimed to determine the effect of the web-based support program based on the health promotion model on maternal infant health in pregnant women with preeclampsia.

NCT ID: NCT05016440 Withdrawn - Preeclampsia Clinical Trials

Lisinopril for Renal Protection in Postpartum Preeclamptic Women

Start date: September 2015
Phase: N/A
Study type: Interventional

There may be a role for Lisinopril in improving renal protection in post-partum women who had preeclampsia during pregnancy. The aim of this study is to determine whether routine initiation of Lisinopril after delivery, in women who had preeclampsia while they were pregnant, can control high blood pressure and improve kidney function.