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Postoperative Complications clinical trials

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NCT ID: NCT02057653 Completed - Clinical trials for Postoperative Complications

Evaluation of Goal-Directed Intraoperative Hemodynamic Optimization Protocol

Start date: November 2013
Phase:
Study type: Observational

As part of a quality assurance program, the Department of Anesthesiology implemented a Goal-Directed Fluid Management training course for all physicians and nurses to provide goal-directed fluid management. We intend to assess whether there has been any improvement in patient outcomes by analyzing de-identified clinical information that are readily available via the medical center electronic medical record system. The time-frame we are interested in is one year before and one year after the Goal-Directed Fluid Management training curriculum (June 15, 2011 to September 15, 2013).

NCT ID: NCT02055027 Completed - Clinical trials for Sleep Apnea, Obstructive

Adherence to Continuous Positive Airway Pressure Among Obstructive Sleep Apnoea Patients.

Start date: February 2008
Phase: N/A
Study type: Observational

Prospective study designed to identify factors that would predict patient adherence to CPAP (Continuous Positive Airway Pressure) therapy.

NCT ID: NCT02050451 Completed - Bladder Cancer Clinical Trials

Perioperative Oral Nutrition Intervention for Patients Undergoing Radical Cystectomy

Start date: March 2014
Phase: N/A
Study type: Interventional

The current study is designed to assess the impact of an enriched oral nutritional shake (Ensure Plus®) to improve the nutritional status and patient outcome after surgery to remove a cancerous bladder (radical cystectomy). Radical cystectomy with urinary diversion using a segment of intestine is the standard of care for invasive bladder cancer. This operation has a high complication rate and several studies have shown that this may be directly related to poor nutrition. The investigators believe that patients who consume an enriched nutritional shake before and after surgery will improve their nutrition status and experience fewer complications, shorter length of stay and less readmissions compared to those who do not. Patients who are scheduled to undergo elective radical cystectomy will be eligible for enrollment. Once enrolled, they will be randomly assigned to one of two groups. One group will be offered Ensure Plus® twice daily for 2 weeks before and 4 weeks after their surgery and the other will be offered a daily over-the-counter multivitamin for the same period of time. The investigators will follow both groups for up to 30 days after their surgery and compare clinical outcomes such as: complication rates, length of stay, readmission rates and mortality as well as measure serum markers of nutrition status and assess changes in body composition.

NCT ID: NCT02041403 Completed - Outcome Clinical Trials

RENAL RESISTIVE INDEX POST-OPERATIVE COMPLICATIONS IN MAJOR SURGERY?

Start date: June 2012
Phase: N/A
Study type: Observational

An observational trial aiming to verify whether does any relationship exist between renal resistive index and postoperative outcome in major high risk surgery

NCT ID: NCT02025075 Completed - Clinical trials for Postoperative Complications

Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.

Start date: January 2014
Phase: N/A
Study type: Interventional

The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery. Furthermore, we will investigate if the level of NMB influences intraoperative hemodynamic and cerebral oxygenation.

NCT ID: NCT02024776 Completed - High-risk Patient Clinical Trials

Effectiveness of Prehabilitation Program for High-risk Patients Underwent Abdominal Surgery

Start date: February 1, 2014
Phase: N/A
Study type: Interventional

Despite recent advances, morbidity and mortality associated to major abdominal surgery is significant. A poor physical condition and functional status reduces the ability of a person to cope, mentally and physically, with hospitalization and surgery and may compromise functional recovery, potentially leading to postoperative complications and death. Prehabilitation aims to enhance functional capacity preoperatively for better toleration of surgery and to facilitate recovery and eventually the prognosis of the surgical patient. Whereas the benefits of cardiopulmonary fitness programs are well established, the accessibility, sustainability of effects, and impact on the surgical outcome of these programs are unsolved issues. Wellness programs based on integrated care services supported by Information and Communication Technology (ICT) can overcome such limitations. The investigators hypothesized that a prehabilitation program, inducing beneficial effects on exercise capacity, may improve the surgical outcome in high-risk patients. Moreover, ICT support may contribute to increase the adherence and sustainability of this intervention.

NCT ID: NCT02020863 Completed - Clinical trials for Postoperative Complications

Closed-Loop Fluid Administration System Using Hemodynamic Monitors

Start date: November 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility of a closed-loop (automated) fluid administration system to deliver fluids using feedback from standard operating room hemodynamic monitors. In standard anesthesia care the rate of IV fluid administration to the patient is determined by the anesthesiologist caring for the patient. In this study protocol, the rate of fluid administration will be determined instead by the closed-loop (automated) control system under the supervision of the anesthesiologist. The system will independently decide when to give fluid and at what rate; the supervising anesthesiologist will monitor the system to ensure appropriate volumes are being delivered and to intervene if necessary.

NCT ID: NCT02007096 Completed - Pain, Postoperative Clinical Trials

Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?

Start date: August 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if a Transabdominal Plane Block will decrease patient pain and pain medication use after a laparoscopic ventral (ventral, umbilical, incisional) hernia repair with mesh.

NCT ID: NCT01995786 Completed - Clinical trials for Postoperative Complications

Clinical Outcomes and Costs Analyses in Use of Goal Directed Therapy

Start date: January 2012
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate clinical and economic impact of Goal Directed Fluid Therapy according to NICE haemodynamic protocol. Haemodynamic parameters were assessed using automated pulse contour analysis (Flotrac/Vigileo®). A specific dedicated software has been developed to perform clinical and expenditures data collection, both retrospective and prospective data are archived.

NCT ID: NCT01987648 Completed - Clinical trials for Postoperative Complications

eCRANIO Trial Study on Elective CRAniotomies: Postoperative Neurointensive Care, Imaging and Outcome

eCRANIO
Start date: November 1, 2011
Phase:
Study type: Observational

Regarding the postoperative care strategies following elective craniotomy procedures there is little evidence. Many neurosurgical departments prefer these patients to remain intubated and sedated for many hours postoperatively to minimize hemodynamic and respiratory distress in fear of early postoperative complications such as rebleeding or seizures. In this prospective observational study the investigators aim to show that early tracheal extubation following elective brain surgery is feasible and safe.