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Postoperative Complications clinical trials

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NCT ID: NCT02238561 Completed - Clinical trials for Post-operative Complications

The Cost in Oxygen of Surgical Trauma

Start date: November 2014
Phase: N/A
Study type: Observational

The investigators will examine the relationship between post-operative oxygen consumption (using non-invasive measurement technology ) and complications in patients having contemporary major abdominal surgery. The investigators hypothesis is that major surgery may trigger a physiological stress response that results in an increase in post-operative metabolic demand and oxygen consumption (V̇O2) which must be met by an increased oxygen delivery (DO2). 1. To determine the feasibility of non-invasive measurement of oxygen consumption (V̇O2) using indirect calorimetry in a cohort of patients 2. To determine the feasibility of non-invasive measurement of oxygen delivery (DO2) in the same cohort using non-invasive measures of cardiac output, oxygen saturation and haemoglobin (pulse wave transit time and co-oximetry techniques)

NCT ID: NCT02229591 Completed - Clinical trials for Postoperative Respiratory Complications

Expiratory Flow Limitation and Postoperative Complications

Start date: January 2013
Phase: N/A
Study type: Observational

Expiratory flow limitation (EFL) occurs when flow ceases to increase with increasing expiratory effort. In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea. Our hypothesis is that EFL should affect post operative outcomes like incidence of pulmonary complication and length of stay in hospital

NCT ID: NCT02190903 Completed - Delirium Clinical Trials

A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia

Start date: October 2013
Phase: N/A
Study type: Interventional

This pilot project will address the gaps in knowledge regarding the effect of anesthetic technique on the risk of delirium through an adequately-powered trial employing standardized regimens for treatment and outcome assessment to test the hypothesis that use of spinal versus general anesthesia decreases the risk of delirium after hip fracture surgery.

NCT ID: NCT02188446 Completed - Bladder Cancer Clinical Trials

Intensive Smoking and Alcohol Cessation Intervention in Bladder Cancer Surgery Patients

STOP-OP
Start date: November 2014
Phase: N/A
Study type: Interventional

Radical cystectomy provides the best cancer-specific survival for muscle-invasive urothelial cancer. However the postoperative morbidity remains at 11-68 %. Smoking and alcohol consumption above two drinks per day is associated with an increased risk of postoperative morbidity. Six-eight weeks of smoking and alcohol abstinence prior to elective surgery is recommended to reduce this risk, but for cancer patients the preoperative period is often very short. This randomised clinical trial (STOP-OP) will reach a conclusion on the effect of a new Gold Standard Programme for both smoking and alcohol cessation Intervention using the Gold Standard Programme (GSP) on the frequency and severity of postoperative complications after bladder cancer surgery.

NCT ID: NCT02164682 Completed - Hypospadias Clinical Trials

The Effect of Caudal Block on the Postoperative Complications in Pediatric Patients After Hypospadias Repair

Start date: June 2014
Phase: N/A
Study type: Observational

Hypospadias refers to a disease represented by a congenital defect in the urethra meatus (urinary opening) in male children. Due to the postoperative pain, symptoms such as discomfort, agitation, and restlessness are generally found. In particular, young children with restlessness often express their pain or discomfort with their bodies because they are unable to express it in words. This severe restlessness may make an operated region unstable, accompanying bleeding, infection, or other surgery-related complications. Because postoperative pain control is very important, neuraxial block techniques such as epidural block or caudal block have been employed in addition to a penile dorsal nerve block. Although the neuraxial block technique including the caudal block is an easy and safe method and has an excellent effect, the neuraxial block technique poses a potential risk in the procedure. In addition, with respect to the surgical prognosis, it has been reported that penile engorgement may cause penile vasodilation, resulting in oozing at the surgical region or other surgical complications. However, there has not been a report on the increase of postoperative complications by penile vasodilation or on the difference in the recovery or surgical prognosis according to the types of pain control for young patients.

NCT ID: NCT02155868 Completed - Clinical trials for Postoperative Complications

Role of Cerebral Oximetry in Reducing Postoperative Morbidity Following Cardiac Surgery

Start date: June 2014
Phase: N/A
Study type: Interventional

Cerebral oximetry employing near-infrared spectroscopy (NIRS) is a non-invasive modality used to estimate regional cerebral oxygen content saturation (rSO2). Near-infrared spectroscopy has increasingly been used in perioperative setting of heart surgery and many studies have outlined an increased incidence of postoperative morbidity in patients with significant perioperative reductions in rSO2. Although a relationship between rSO2 reductions and adverse outcomes has been reported, there is not compelling evidence that interventions to correct rSO2 during cardiac surgery lead to improved clinical outcomes. Hypothesis of the study is that interventions to normalize intraoperatively decreased cerebral rSO2 would reduce the overall incidence of postoperative complications in high-risk cardiac surgery patients.

NCT ID: NCT02150486 Completed - Myocardial Injury Clinical Trials

Myocardial Injury and Postoperative Complications

MICOLON
Start date: June 2012
Phase: N/A
Study type: Observational

To determine whether perioperative myocardial injury is associated with adverse outcome in patients scheduled for major abdominal surgery.

NCT ID: NCT02143128 Completed - Postoperative Pain Clinical Trials

Efficacy Side-effect Score (ESS): Development and Evaluation of a New Tool for Patients After Surgery

ESScore
Start date: March 2014
Phase: N/A
Study type: Interventional

We hypothesized that better control of postoperative pain treatment and its side effects by monitoring ESS might influence the degree of mobility and morbidity in surgical patients and consequently reduce LOS. Thus, our aim was to validate the influence of recording ESS and the application of a "call-out algorithm" on LOS in two university hospitals in which the routine policy of registration of pain had not been adopted yet.

NCT ID: NCT02102217 Completed - Clinical trials for Postoperative Complications

the PRECious Trial: PREdiction of Complications

PRECious
Start date: December 2015
Phase: N/A
Study type: Interventional

20% of patients who undergo major abdominal surgery will have a major complication, which requires invasive treatment and is associated with increased mortality, morbidity, hospital stay and intensive care stay. A quality control algorithm after Major Abdominal Surgery (MAS) aimed at early identification of patients at risk of developing major complications can decrease associated morbidity and mortality. Literature studies show promising results for C-reactive protein as an early marker for postoperative complications, however clinical significance has yet to be determined. Here the investigators propose a randomized clinical trial in order to determine the effect of postoperative monitoring with standardized CRP measurements on postoperative morbidity and mortality, if CRP levels exceed 140 mg/L additional CT-scan imaging will be conducted.

NCT ID: NCT02084862 Completed - Clinical trials for Tracheostomy Complications

Ultrasound Guided Percutaneous Tracheostomy Compared to Bronchoscopy Guided Percutaneous Tracheostomy

TRACHUS
Start date: March 2014
Phase: N/A
Study type: Interventional

TRACHUS trial is a randomized non-inferiority trial designed to evaluate the safety and efficacy of ultrasound guided percutaneous tracheostomy compared to bronchoscopy guided percutaneous tracheostomy.