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Postmenopausal Symptoms clinical trials

View clinical trials related to Postmenopausal Symptoms.

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NCT ID: NCT03684096 Completed - Breast Cancer Clinical Trials

Effect of Non-estrogenic Pollen Extract PCC-100 on Hot Flushes

Start date: October 15, 2018
Phase: N/A
Study type: Interventional

Many postmenopausal women have vasomotor symptoms during adjuvant hormonal treatment for breast cancer. PCC-100 is a pollen extract used for alleviation of postmenopausal symptoms. In a randomised, double blinded study pollen extract PCC-100 will be used to treat vasomotor complaints in postmenopausal women under adjuvant hormonal treatment and also in menopausal women without a history of breast cancer.

NCT ID: NCT03682601 Terminated - Dyspareunia Clinical Trials

Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment

Start date: August 30, 2018
Phase: Phase 2
Study type: Interventional

This study will evaluate the use of topical 5 or 10% sinecatechins, a botanical drug derived from green tea for the alleviation of sexual pain in the area around the vaginal opening (the vulvar vestibule), that is a main source of pain during sexual contact or dyspareunia, in postmenopausal women, with vulvovaginal atrophy. Women may or may not be using estrogens. Half of the women will receive the study drug, 5 or 10% sinecatechins and half will receive placebo. In addition to the reduction or elimination of pain upon penetration, women may also experience increase in lubrication, arousal and intensity of orgasm

NCT ID: NCT03640962 Active, not recruiting - Clinical trials for Postmenopausal Symptoms

Relationship in Sleep With Low Back Pain in Postmenopausal Period

Start date: April 2, 2018
Phase:
Study type: Observational [Patient Registry]

Introduction:The aim of this study was to investigate the incidence of low back pain in postmenopausal period and the relationship between low back pain and emotional state,sleep and quality of life i aimed at investigating low back pain during postmenopausal period of women and its correlation with the emotional state,sleep quality and the quality of life of woman. Method:This cross-sectional study was conducted in 368 postmenopausal women aged between 40 and 65 years.All participants were recorded frequency and severity of low back pain,depressive symptoms and anxiety,quality of life and sleep quality.Outcome measures are described in more detail below.

NCT ID: NCT03640754 Completed - Clinical trials for Postmenopausal Symptoms

A Study of the Safety and Effect of Repeated Administration of G-CSF on Hot Flashes in Postmenopausal Women

Start date: August 6, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of repeated administration of G-CSF for the treatment of hot flashes and vasomotor symptoms in women with naturally-occurring or surgically induced menopause. G-CSF will be administered three times at 28 day intervals to postmenopausal women, ages 40 to 65, suffering at least 49 moderate to severe hot flashes per week.

NCT ID: NCT03572153 Completed - Breast Cancer Clinical Trials

A Mind-Body Intervention for Hot Flash Management

Start date: November 15, 2018
Phase: N/A
Study type: Interventional

The long-term goal of this program of research is to determine safe and effective non-hormonal interventions for menopausal symptoms. The main goal of this study is to evaluate whether self-administered hypnosis can be used to significantly reduce hot flashes more than self-administered white noise hypnosis over 6 weeks of home practice. The investigators are also examining the impact of each hypnosis group on sleep, anxiety, perceived and measured stress, heart rate variability, and daily activities.

NCT ID: NCT03150407 Completed - Clinical trials for Postmenopausal Symptoms

Use of J3 Bioscience Lubricating Intravaginal Ring VR101 to Relieve the Symptoms of Vaginal Dryness

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

This investigation is designed to demonstrate the safety and efficacy of the VR101 lubricating intravaginal ring (IVR) in treating the symptoms of vaginal dryness. In the proposed investigation, participants will use VR101 devices and sham control rings in a crossover study design. All participants who successfully complete the crossover study will be given the option to continue using VR101 for a total of 13 consecutive weeks to evaluate the long-term safety of the new device.

NCT ID: NCT03137849 Completed - Hypertension Clinical Trials

Yoga Poses and Breath Control Cardiovascular Changes in Hypertensive Post-Menopause Women

YOGINI
Start date: July 18, 2017
Phase: N/A
Study type: Interventional

Autonomic and endothelial imbalance in post menopause women raise the need to manage cardiovascular risk. Yoga poses and breathing control present controversial results on prevention and treatment of hypertension.. The aim of this study is to compare the effect of 12 week intervention based on yoga poses and their muscle contractions known as bandhas (pelvic floor, core and throat/neck) and ujjayi pranayama (victorious breath) on autonomic modulation, endothelial function, arterial stiffness, aerobic capacity and cognitive function of hypertensive post-menopausal women.

NCT ID: NCT02237079 Completed - Obesity Clinical Trials

Bazedoxifene/Conjugated Estrogens (BZA/CE) Improvement of Metabolism (BIM)

BIM
Start date: December 2014
Phase: Phase 4
Study type: Interventional

The goal of this pilot clinical study is to perform a randomized placebo-controlled study to assess the beneficial effect of a 3 month-treatment with Bazedoxifene/Conjugated Estrogens (BZA/CE) vs. placebo on glucose homeostasis and body composition in 20 post-menopausal women. The recruitment will be performed at Tulane Health Sciences Center.

NCT ID: NCT01829919 Completed - Clinical trials for Postmenopausal Symptoms

Pharmacokinetic Evaluation of Brisdelleā„¢ (Formerly Known as Mesafem) Following Single & Repeat Oral Administration in Healthy Postmenopausal Women

N30-005
Start date: July 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the pharmacokinetics (absorption, breakdown and elimination from the body), safety and tolerability of Brisdelle (paroxetine mesylate) Capsules 7.5 mg when given as a single dose and multiple doses.

NCT ID: NCT01361308 Completed - Clinical trials for Postmenopausal Symptoms

Efficacy/Safety Study of Brisdelleā„¢ (Formerly Known as Mesafem) in the Treatment of Vasomotor Symptoms (VMS)

N30-003
Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety & efficacy of Brisdelle (paroxetine mesylate) Capsules 7.5 mg for treatment of vasomotor symptoms (VMS) associated with menopause.