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Safety of Maraviroc for Post-stroke Depression — MRV-PSD  

Post-stroke Depression Clinical Trial

Official title:
Safety of Maraviroc for Post-stroke Depression (Proof-of-concept)

Clinical Trial Summary

Post-stroke depression (PSD) is a barrier to effective rehabilitation and recovery after stroke. Current treatment options are limited and there is an unmet need for specific and effective therapeutic options. Objective: To examine the safety and efficacy of Maraviroc, a CCR5 antagonist, as a possible add-on treatment option for PSD, in an open-labeled proof-of-concept clinical trial. Design, Setting, and Participants: A 10-week trial of daily oral 300 mg Maraviroc in ten patients with subcortical stroke suffering from PSD. Follow-up: eight weeks after completing treatment. Main Outcome Measure: A change in the Montgomery-Asberg Depression Rating Scale (MADRS).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05932550
Study type Interventional
Source Tel-Aviv Sourasky Medical Center
Contact
Status Completed
Phase Phase 2
Start date August 4, 2020
Completion date August 4, 2022
View Details
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