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Post-operative Pain clinical trials

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NCT ID: NCT02555423 Not yet recruiting - Post-operative Pain Clinical Trials

The Effects of Serratus Plane Block Performed Under Direct Vision on Post-operative Pain in Breast Surgery

Start date: October 2015
Phase: N/A
Study type: Interventional

The aim of the study is to determine the effectiveness of serratus place block in the control of post-operative pain following mastectomy. The investigators will compare one group of patients receiving serratus plane block and wound infiltration to a control group receiving a saline injection into serratus anterior and wound infiltration with local anaesthetic only. The investigators will compare our results to the National Mastectomy and Breast Reconstruction Audit's reported rate of 6.2% of patients reporting severe pain following mastectomy to see if there is an improvement of the national standard. In the serratus block group, the investigators expect a 50% decrease in the number of patients who report severe pain day one post operatively.

NCT ID: NCT02300480 Not yet recruiting - Post-operative Pain Clinical Trials

Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial

Start date: December 2014
Phase: Phase 4
Study type: Interventional

Chronic pain after laparoscopic cholecystectomy (LC) is a common complication with an incidence ranging between 3-56%. In many cases, however, the cause chronic pain after LC remains unknown and visceral hyperalgesia and central sensitization have been suggested to be part of the pathophysiology. So the purpose of this study is to determine whether Calot's Triangle Block (CTB) combined with patient controlled intravenous analgesia (PCIA) is superior to PCIA in reducing the incidence of chronic pain after LC.

NCT ID: NCT02292095 Not yet recruiting - Inguinal Hernia Clinical Trials

Effects of Transverse Abdominis Plane Block Guided by Ultrasound on the Postoperative Analgesia and Quality of Lives Among the Patients Undergo Inguinal Hernia Repair

Start date: January 2016
Phase: Phase 4
Study type: Interventional

The incidence of post-operative pain after open inguinal hernia repair is high and impair the quality of lives of the patients.The purpose of this study is to determine whether transverse abdominis plane block combined with intravenous patient controlled analgesia is superior to intravenous patient controlled analgesia in improving the quality of life and reducing the incidence of chronic post-surgical pain

NCT ID: NCT01278264 Not yet recruiting - Post Operative Pain Clinical Trials

Transversus Abdominis Plane Blocks With Abdominoplasty

TAPA
Start date: June 2011
Phase: Phase 4
Study type: Interventional

Comparing morphine consumption and recovery with two different TAP block techniques after abdominoplasty.

NCT ID: NCT00849719 Not yet recruiting - Post Operative Pain Clinical Trials

Effects of a Combination of IV-PCA With Continuous IV Infusion of MO, Versus IV-PCA MO on Postoperative Pain

Start date: April 2009
Phase: N/A
Study type: Interventional

After major surgery, such as abdominal or thoracic surgery, the majority of patients experience moderate to severe pain that may not be optimally controlled. Inadequate pain relief may lead to complications that can hinder rehabilitation and slow recovery. Morphine (MO) is the most commonly used opioid for the treatment of post-surgical pain (14). The preferred method of administration nowadays is intravenous patient-controlled analgesia (PCA). In contrast, Continuous infusion of intravenous morphine (CIVM) is seldom used in Post-Anesthesia Care Units (PACUs) for acute postoperative pain, due to concerns of cardio-respiratory deterioration, even though different studies have found this technique of administration effective and safe (in terms of opioid-related symptoms.As part of our efforts to improve postoperative pain management in the Tel Aviv Sourasky Medical Center's PACU, we wish to determine if combining CIVM with IV PCA will be superior over IV PCA only for the treatment of postoperative pain following major abdominal or thoracic surgery.Our hypothesis is that the continuous infusion, even if given at a relatively low dose, would enable the build-up of pharmacologically effective MO blood level, thus providing an overall better control of pain.

NCT ID: NCT00643032 Not yet recruiting - Post-Operative Pain Clinical Trials

Preoperative Anxiety and Postoperative Pain in Children

Start date: March 2008
Phase: Phase 4
Study type: Interventional

We wish to study which method of local injection of analgesic (before or during surgery) is the more effective method to reduce post-operative pain in children. In addition, we wish to study which pre-operative educational intervention is more effective in reducing anxiety in children and their family.