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Post-operative Pain clinical trials

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NCT ID: NCT04371445 Enrolling by invitation - Post-operative Pain Clinical Trials

Dextenza in the Post-op Management of Vitreoretinal Surgeries

Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

This study will assess the control of inflammation at days 1, 7, 14, and 21 days following the vitreoretinal surgical procedure analyzing two randomized study arms: Intracanalicular dexamethasone insert group or topical steroid drop group. Patients must be 18 years of age and older, of any race and either sex, requiring surgery with the procedure type of pars plana vitrectomy for either the indication of macular hole, epiretinal membrane removal, or vitreomacular traction.

NCT ID: NCT04360135 Withdrawn - Post Operative Pain Clinical Trials

Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy

Start date: May 6, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This study is investigating whether administration of acetaminophen the day before surgery improves post operative pain following minimally invasive hysterectomy. Patients will receive either acetaminophen or placebo to take twice per day the day prior to their scheduled surgery. The morning of surgery all participants will receive oral acetaminophen at least 30 minutes prior to surgery. The investigators will examine whether there is a difference in post operative pain between the two groups.

NCT ID: NCT04346407 Enrolling by invitation - Post-operative Pain Clinical Trials

Dronabinol for Post-operative Pain After Lumbar Fusion

Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

Impact of 2.5mg of oral Dronabinol daily versus placebo on post-operative opioid consumption on patients aged 18 to 65 years old undergoing 1 to 3 level posterolateral fusion

NCT ID: NCT04342065 Completed - Post-Operative Pain Clinical Trials

Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery

Start date: January 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The anti-epileptic drugs such as gabapentin and other non-steroidal anti-inflammatory drugs (NSAID) such as celecoxib were used as a part of multimodal analgesia to control such pain. Gabapentin is an anticonvulsant drug that has analgesic effect in post-herpetic neuralgia, diabetic neuropathy, and neuropathic pain. Celecoxib is one of the NSAIDs, that its analgesic effect is reported in various studies by cyclooxygenase-2 (COX-2) inhibitor. The aim of this randomized double-blinded study was to asses and compare the efficacy of using gabapentin versus celecoxib as a part of multimodal analgesia in perioperative hemodynamic control and pain relief in patients underwent posterior approach lumbar spine disc fixation surgery.

NCT ID: NCT04300660 Recruiting - Neuropathic Pain Clinical Trials

Post-Operative Pain After Recovery in Thoracic Surgery

POPARTS
Start date: October 25, 2017
Phase:
Study type: Observational [Patient Registry]

Persistent pain after surgery has significant physical and mental consequences for the patient, as well as a significant economic impact on health systems. Neuropathic pain is caused by direct or indirect damage to the somatosensitive system. In thoracic surgery, chronic neuropathic pain is represented by Post-Thoracotomic Pain Syndrome (PTPS), defined as recurrent or persistent pain in the thoracotomy scar site that persists for more than 3-6 months. Currently, in literature, the prevalence of PTPS is extremely variable. This prospective observational study aims to assess the incidence of pain in the weeks and months following surgery and to assess whether and how the presence of painful symptoms changes the patient's quality of life.

NCT ID: NCT04197531 Completed - Post Operative Pain Clinical Trials

Postoperative Pain After the Use of Different Last Irrigation Method During Root Canal Treatment in Primary Teeth

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

This study was to evaluate and compare the postoperative pain levels after using EndoActivator and conventional endodontic syringe irrigation in root canal therapy of primary molars.

NCT ID: NCT04182828 Recruiting - Post-operative Pain Clinical Trials

Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial

Start date: November 25, 2019
Phase: Phase 4
Study type: Interventional

Lidocaine is a drug that has multiple uses. One of these is that when intravenously administered it is effective in reducing post-operative pain. The aim of this study is to investigate the beneficial effects of intravenous lignocaine on reducing pain, nausea and vomiting after laparoscopic cholecystectomy. Also, by this research, we are aiming to find a suitable alternative analgesic.

NCT ID: NCT04176770 Not yet recruiting - Post Operative Pain Clinical Trials

Comparaison of ESP Block and TAP Block

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

This study aim to compare the efficiency and the analgesic effect of Erector Spinal Plane Block versus TAP Block after laparoscopic cholecystectomy.

NCT ID: NCT04149964 Completed - Post-operative Pain Clinical Trials

Postoperative Pain Control in Septum and Sinus Surgery

Start date: November 27, 2019
Phase: Phase 4
Study type: Interventional

This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients. Participants will be randomized like a flip of a coin to either the standard of care pain treatment of acetaminophen 325 mg as needed for pain plus opiates (acetaminophen/hydrocodone) as needed for breakthrough pain; OR to the study arm of acetaminophen 650 mg every 6 hours plus opiates (Oxycodone)as needed for breakthrough pain.

NCT ID: NCT04135534 Not yet recruiting - Post Operative Pain Clinical Trials

Find the Adequate Dose of Nalbuphine for Laparoscopic Cholecystectomy

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

This study evaluate the adequate dose of mutonpain for laparoscopic cholecystectomy in the management of post operative pain. The investigators will randomize patients into three groups to compare the analgesia effects and side effects.