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Post-operative Pain clinical trials

View clinical trials related to Post-operative Pain.

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NCT ID: NCT05317312 Completed - Pain Clinical Trials

Study of MR-107A-02 in the Treatment of Post Surgical Dental Pain.

Start date: March 31, 2022
Phase: Phase 2
Study type: Interventional

MR-107A-02 is being studied to investigate its efficacy, safety and dose-response after dental surgery.

NCT ID: NCT05315479 Terminated - Post Operative Pain Clinical Trials

Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following Surgery

Start date: February 24, 2022
Phase: Phase 4
Study type: Interventional

This study is an open-label, multicenter evaluation of Safety and Pharmacokinetics of N1539 in postoperative Pediatric subjects aged 2 to <17 years.

NCT ID: NCT05310266 Completed - Surgery Clinical Trials

Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy

Start date: April 6, 2020
Phase: N/A
Study type: Interventional

Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.

NCT ID: NCT05306535 Completed - Post Operative Pain Clinical Trials

Effect of Occlusal Reduction on Relief of Pain and Sensitivity to Percussion in Patients With Irreversible Pulpitis

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

One of the most important aspects of endodontic practice is to abate pain during and post root canal treatment. An endodontist by all means should provide a painless endodontic treatment to their patients. This study is carried out to determine the effect of occlusal reduction on relief of pain and percussion in patients with irreversible pulpitis and symptomatic apical periodontitis treated in a single visit root canal treatment. Pain will be assessed preoperatively and then post operatively after completion of the root canal at 6 hours, 12 hours, 24 hours, 48 hours and 72 hours following obturation of root canal.

NCT ID: NCT05305742 Not yet recruiting - Post Operative Pain Clinical Trials

Evaluation of Postoperative Pain and Bacterial Load Reduction With ProTaper Ultimate Versus ProTaper Gold Rotary Systems

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

This study aims to research the effect of different instrument designs by comparing protaper ultimate versus protaper gold systems on root canal preparation by evaluating bacterial count reduction and post-operative pain following single visit treatment in patients with necrotic pulp in maxillary premolar teeth.

NCT ID: NCT05300854 Completed - Post Operative Pain Clinical Trials

Serratus Block Versus Paravertebral Block for Post Thoracotomy Pain Relief

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This double-blinded, randomized controlled study was done on 60 patients older than 18 years undergoing thoracotomy. Patients were allocated into two equal groups (30 patients each). Group S: Standard anesthesia in addition to SPB. II. Group P: Standard anesthesia in addition to PVB.

NCT ID: NCT05299788 Completed - Pain, Acute Clinical Trials

Post-thoracotomy Pain Management With Active External Warming and Ice Application

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption. The research is a quasi-experimental design with control and study groups.

NCT ID: NCT05284695 Completed - Clinical trials for Bariatric Surgery Candidate

THE EFFICIENCY OF FASCIAL PLANE BLOCKS IN BARIATRIC SURGERY

Start date: January 1, 2019
Phase:
Study type: Observational

Bariatric surgery effectively produces weight loss and reduces obesity-related comorbidities. Although it is mostly performed with minimally invasive techniques, the patients may still suffer from moderate-to-severe pain immediately after surgery [1]. Opioids remain the first choice for multimodal analgesia in the treatment of postoperative pain. Providing analgesia after bariatric surgery might be challenging due to a high prevalence of obstructive sleep apnea syndrome and the increased sensitivity to respiratory depression triggered by opioid overuse after surgeryThe most common plane block techniques utilized during laparoscopic bariatric surgery are transversus abdominis plane block (TAP), rectus sheath block (RB), the erector spinae plane block (ESPB) and the external oblique intercostal block (EOI). In this study, we have evaluated the auxiliary benefit of these various techniques in reduction of the postoperative in bariatric surgery. patients who had laparoscopic bariatric surgery at VKV American Hospital between January 2019 and December 2021 were reviewed retrospectively.

NCT ID: NCT05283499 Completed - Post Operative Pain Clinical Trials

Opioid Analgesic Reduction Study (OARS) - Pilot

OARS-Pilot
Start date: July 6, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to test protocols being developed for the conduct of a large sale multi-site clinical trial which will compare opioids to non-opioids for managing post-surgical impacted 3rd molar extraction pain.

NCT ID: NCT05281081 Completed - Post Operative Pain Clinical Trials

Intraperitoneal Instillation of Levobupivacaine With Morphine Versus Levobupivacaine With Magnesium Sulfate for Postoperative Analgesia

Start date: January 1, 2021
Phase: Phase 4
Study type: Interventional

This is a prospective randomized study that included 60 patients and was divided into two equal groups of patients who were scheduled for LC, Ages 18 and 60 years, both sexes, ASA I-II and BMI 19 - 39. Group A received 30 ml levobupivacaine (0.25%) plus 3 mg morphine intraperitoneal at the site of surgery in the bed of the gallbladder via the navel port with the patient in a Trendelenburg position, Group B received 30 ml levobupivacaine (0.25%) plus 50 mg/kg magnesium sulfate in the same pattern as in the A group.