Clinical Trials Logo

Post-Dural Puncture Headache clinical trials

View clinical trials related to Post-Dural Puncture Headache.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT06394024 Completed - Clinical trials for Postdural Puncture Headache

Examination of Postdural Puncture Headache Frequency, Predisposing Factors and Treatment

PDPH
Start date: November 1, 2023
Phase:
Study type: Observational

Post-dural puncture headache (PDPH) is one of the most important complications of neuraxial blocks and lumbar interventions for cerebrospinal fluid (CSF) examination. It occurs due to tear in the dura mater and loss of cerebrospinal fluid (CSF) after intrathecal or epidural interventions.The incidence of PDPH depends on the thickness of the needle used and the type of tip. Headaches are more common with thick needles than with thin needles.In our study, postdural puncture headache in patients whose surgery was planned and spinal anesthesia was applied at Süleyman Demirel University faculty of medicine;frequency, predisposing factors, treatment intended to examine.

NCT ID: NCT06380764 Completed - Clinical trials for Postdural Puncture Headache

Greater Occipital Nerve Block Value in Management of Postdural Puncture Headache

Start date: March 2, 2023
Phase: N/A
Study type: Interventional

Neuraxial techniques are well tolerated and effective options for labor analgesia and anesthesia for caesarean section, and may protect high risk women against severe maternal morbidity. However, neuraxial techniques still have drawbacks especially postdural puncture headache (PDPH) and may be associated with chronic headache, back pain and postnatal depression. PDPH is a relatively common acute complication of neuraxial techniques that was traditionally considered benign and self-limiting, but it significantly impacts patients' general health and quality of life. Greater Occipital Nerve (GON) originates from C2-3 segments and through its muscular relations it is divided as proximal and distal parts; the most proximal part lies between obliquus capitis inferior and semispinalis and then passes through the semispinalis to pierce the trapezius muscle. In distal region of trapezius fascia, the GON is crossed by the occipital artery and exits the trapezius fascia into the nuchal line about 5-cm lateral to midline. Functionally, GON provides motor supplies to the muscles while passing through it and its main sensory supply is in the occipital region.

NCT ID: NCT05969119 Completed - Clinical trials for Postdural Puncture Headache

Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache

Start date: July 25, 2023
Phase: Phase 4
Study type: Interventional

Postdural puncture headache (PDPH) is a major complication of neuraxial anesthesia that can occur following spinal anesthesia and with inadvertent Dural puncture during epidural anesthesia. The presence of Pyridostigmine in CSF would be expected to increase the level of acetylcholine in CSF and subsequently in the brain through inhibition of cholinesterase. The increased level of acetylcholine would produce cerebral vasoconstriction.

NCT ID: NCT05777694 Completed - Pregnancy Related Clinical Trials

Postdural Punction Headache After Ceserian Section

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effect of spinal needle type on postdural puncture headache in patients who will undergo cesarean section. The main question[s] it aims to answer are: [Does spinal needle thickness affect postdural puncture headache?] [What is the response of patients who develop postdural puncture headache to treatment?] In cases accepting cesarean section operation under spinal anesthesia, different tables were used with spinal needles, and it will be questioned whether headache will develop in the first 15 days postoperatively. Postdural puncture headache after surgery will be described.

NCT ID: NCT05552404 Completed - Anesthesia Clinical Trials

Postdural Puncture Headache Relief With Aminophylline and SPGB

Start date: October 1, 2022
Phase: Phase 4
Study type: Interventional

The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.

NCT ID: NCT05301387 Completed - Clinical trials for Post-Dural Puncture Headache

The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up

GSP-FOLLOW
Start date: November 26, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the long term effects of the ganglion sphenopalatine block (GSP block) on postdural puncture headache.

NCT ID: NCT05289323 Completed - Clinical trials for Post-Dural Puncture Headache

Effect of Intrathecal Neostigmine on Post-dural Puncture Headache.

Start date: April 25, 2022
Phase: Phase 4
Study type: Interventional

Intravenous neostigmine was recently reported as an effective treatment for PDPH for parturients after intrathecal (IT) block which is postulated to be through its central effects on CSF secretion and cerebral vascular tone modulation. Intrathecal neostigmine has been investigated widely and found to be an effective adjuvant to bupivacaine for postoperative analgesia. The objective of the current study is to investigate the possible prophylactic role of intrathecal neostigmine as an adjuvant to bupivacaine in reducing the incidence and severity of post-dural puncture headache in parturients scheduled for an elective cesarean section.

NCT ID: NCT05253014 Completed - Clinical trials for Post-Dural Puncture Headache

Different Approaches for the Management of Post-dural Puncture Headache

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Detecting the efficacy and safety of trans-nasal sphenopalatine ganglion block using either lidocaine 2% or bupivacaine 0.5 % as a treatment line for post-dural puncture headache

NCT ID: NCT05108688 Completed - Headache Clinical Trials

Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache

Start date: November 15, 2021
Phase: Phase 4
Study type: Interventional

Postdural puncture headache (PDPH) is a potential complication after spinal anesthesia caused by traction on pain-sensitive structures from low cerebrospinal fluid pressure (intracranial hypotension) following a leak of cerebrospinal fluid at the puncture site. Symptoms of this condition include a bilateral frontal or occipital headache that is worse in the upright position, along with nausea, neck pain, dizziness, visual changes, tinnitus, hearing loss, or radicular symptoms in the arms. This study will examine the efficacy of mirtazapine in in the treatment of PDPH after obstetric surgery under spinal anesthesia and compared its efficacy with that of sumatriptan.

NCT ID: NCT04910477 Completed - Clinical trials for Postdural Puncture Headache

Nebulized Dexmedetomidine Versus Neostigmine/Atropine in Postdural Puncture Headache

Start date: June 1, 2021
Phase: Phase 3
Study type: Interventional

In our study, we will compare a new route of nebulization for effectiveness between dexmedetomidine, neostigmine/atropine and saline placebo for females complained of postdural puncture headache (PDPH) after cesarean section.