Effect of Antiviral Therapy on HVPG in Patients With Viral Cirrhosis

Status Not yet recruiting

Clinical Trial Summary

Complications associated with portal hypertension are the leading cause of death in patients with cirrhosis. Until now, hepatic venous pressure gradient (HVPG) - the difference between the wedged hepatic venous pressure (WHVP) and the free hepatic vein pressure (FHVP)- has been the criterion standard to determine portal pressure. Antiviral therapy may decrease HVPG which needs to be verified.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04797910
Study type	Observational
Source	Nanfang Hospital of Southern Medical University
Contact	Xiaofeng Zhang
Phone	+86-18565552050
Email	1282614092@qq.com
Status	Not yet recruiting
Phase
Start date	March 10, 2021
Completion date	December 31, 2022

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05052892` - A Novel Spleen-dedicated Stiffness Measured by FibroScan to Evaluate Cirrhotic Portal Hypertension (CHESS2105)
Recruiting	`NCT05251272` - A Combined Model Based on Spleen Stiffness, Liver Stiffness and Platelets for Assessing Portal Hypertension in Compensated Cirrhosis (CHESS2202)
Recruiting	`NCT05928624` - A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis Patients	N/A
Recruiting	`NCT04578301` - Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease
Not yet recruiting	`NCT05515861` - Evaluation of EUS in Preventing Rebleeding After Endoscopic Cyanoacrylate Injection for Gastric Varices	N/A
Recruiting	`NCT02364297` - TIPS in Fundal Variceal Bleeding (the TFB Study)	N/A
Recruiting	`NCT01358123` - Value of Von Willebrand Factor in Portal Hypertension	N/A
Completed	`NCT00493480` - Danish Carvedilol Study in Portal Hypertension	Phase 3
Recruiting	`NCT06266260` - Evaluation of the Performance of Direct Portal Pressure Measurement by Endoscopic Ultrasound in a Large Cohort of Patients With Advanced Chronic Liver Disease of Different Etiologies and Newly Diagnosed Clinically Significant Portal Hypertension (EVADIPP)
Recruiting	`NCT03277651` - Noninvasive Diagnostic Platform for Liver Fibrosis and Portal Hypertension	N/A
Active, not recruiting	`NCT03736265` - Carvedilol for Prevention of Esophageal Varices Progression	N/A
Completed	`NCT03451149` - Feasibility And Safety Of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation Using A Radiofrequency Guidewire	N/A
Completed	`NCT02994485` - Evaluation Of The Portal Pressure By Doppler Ultrasound In Cirrhotic Patients Before And After Simvastatin	Phase 4
Completed	`NCT01923064` - Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices	N/A
Completed	`NCT01851252` - MBT Versus HVPG in Identifying Responders to Portal Hypertension Therapy	Phase 1
Completed	`NCT01456286` - Randomized Controlled Trial to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patients With Liver Cirrhosis and Portal Hypertension	Phase 2/Phase 3
Completed	`NCT01551966` - Esophageal Capsule Endoscopy in Children	N/A
Completed	`NCT02344719` - Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis	Phase 4
Recruiting	`NCT00414713` - Transfusion Requirements in Gastrointestinal (GI) Bleeding	Phase 4
Completed	`NCT00766805` - Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis	N/A