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Pneumothorax clinical trials

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NCT ID: NCT01572584 Completed - Pneumothorax Clinical Trials

Lung Ultrasound in the Evaluation of Pneumothorax Size

LUS-PNXsize
Start date: December 2011
Phase: N/A
Study type: Observational

Background - Assessment of the percentage of lung collapse is crucial in the therapeutic decision-making of pneumothorax. - The methods normally used to this purpose are radiological. Computerized tomography scan (CT) is highly accurate because it allows the exact evaluation of the volume of the air layer. However, in clinical practice assessment of the volume of pneumothorax mainly relies on the measurement of the inter-pleural distance at conventional chest radiography (CXR). This latter method is inaccurate. - Lung ultrasound is a new method highly accurate in the first diagnosis of pneumothorax, with a sensitivity superior to CXR and similar to CT in case of traumatic pneumothorax. - The scientific community is actually debating about the usefulness of lung ultrasound in the quantification of pneumothorax []. Lung ultrasound can assess the superficial extension of the pneumothorax, but cannot evaluate its volume. Aim - Main purpose of the study is to compare measurement of the superficial extension of pneumothorax on the chest wall obtained by lung ultrasound, to the evaluation of the air volume performed by CT in patients with pneumothorax. - The main hypothesis of the study is that the cut-off between small (<11% of lung collapse) and large (>11% of lung collapse) pneumothorax can be identified by a lung ultrasound evaluation of the superficial extension of pneumothorax. - Second purpose of the study is to compare the accuracies of lung ultrasound and CXR in predicting the volume of pneumothorax assessed by CT. - Secondary hypothesis is that lung ultrasound demonstrates greater accuracy in the prediction of volume of pneumothorax and percentage of lung collapse. Methods - Patients with a diagnosis of pneumothorax confirmed at CT are prospectively enrolled and submitted to lung ultrasound within 20 min from the CT study. - Different locations of the sonographic "lung point" on the chest wall (i.e. the point on the chest wall where the sonographic pattern of the normally aerated lung alternates with the pathologic sonographic pattern of pneumothorax) are compared with different volumes of pneumothorax measured by CT.

NCT ID: NCT01551082 Enrolling by invitation - Lung Cancer Clinical Trials

Outpatient Chest Tube Management Following Thoracic Resection Improves Patient Length of Stay and Satisfaction Without Compromising Outcomes

Start date: March 2012
Phase: N/A
Study type: Observational

Discharging patients home with air leak and chest tube to portable drainage device after thoracic resection is cost effective and safe without compromising patients outcome or satisfaction. Despite good outcomes this practice is not done universally by thoracic surgeons.

NCT ID: NCT01537289 Unknown status - Clinical trials for Traumatic Pneumothorax

Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax

Start date: July 2010
Phase: Phase 3
Study type: Interventional

A small 14-French(F) pigtail catheter (PC) has been shown to work equally well with traditional 32-40F chest tube (CT), especially in traumatic pneumothorax. There are no clinical data on tube-site pain. The investigators hypothesize that PC tube site pain is less than CT.

NCT ID: NCT01522885 Completed - Pneumothorax Clinical Trials

KatGuide Method Versus Conventional Method at Insertion of Chest Tube

KatGuide
Start date: April 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether if KatGuide (a new developed medical device) improves the placing of a large bore chest tube in the pleural cavity compared to the conventional method.

NCT ID: NCT01463553 Recruiting - Pneumothorax Clinical Trials

Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS

Start date: July 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to: 1. Evaluate the validity of using abnormal characteristics of the pneumothorax line, as evaluated from chest X-ray film, as the operative indications for video-assisted thoracic surgery (VATS) on primary spontaneous pneumothorax (PSP). 2. Through a randomized double blind controlled trial on patients whose PSP was caused by lung bullae, evaluate the effectiveness of pleurodesis in terms of the rate of recurrence of PSP and the trauma of the operation on patients. 3. Based on the findings, establish selection standards for the timing of surgery to treat PSP by VATS and establish technical specifications for performing operations on different types of lung bullae. The goal is to improve the diagnosis and treatment of PSP so as to reduce the recurrence rate of pneumothorax, reduce the trauma of operation, shorten hospital stays and postoperative recovery time, and provide better services for returning to everyday life and improving the quality of life for patients.

NCT ID: NCT01388803 Completed - Pneumothorax Clinical Trials

The Depth of Right Bronchial Blocker Placement in Taiwanese in Video-assisted Thoracoscopic Surgery(VATS)

Start date: January 2010
Phase: N/A
Study type: Observational

A retrospective study to demonstrate the optimal depth of right side bronchial blocker for complete right lung separation. Data were collected from all patients who completed right side VATS with right side BB from Jan 2010 through Nov 2010.

NCT ID: NCT01329432 Recruiting - Clinical trials for Bronchopulmonary Dysplasia

Surfactant Administration During Spontaneous Breathing

TAKE CARE
Start date: December 2010
Phase: Phase 4
Study type: Interventional

Spontaneous breathing supported by nasal continuous positive airway pressure (nCPAP) is thought to have some advantages compared with mechanical ventilation in premature infants. In addition, early surfactant administration has been shown to be superior to delayed use. The aim of this pilot study was to describe the feasibility of TAKE CARE (early administration of surfactant in spontaneous breathing) procedure and compare its short-term and long-term results with InSurE procedure.

NCT ID: NCT01192217 Completed - Pneumothorax Clinical Trials

Video-assisted Thoracic Surgery (VATS) Versus Axillary Mini-thoracotomy for the Treatment of Recurrent Spontaneous Pneumothorax

Start date: January 2006
Phase: N/A
Study type: Interventional

The investigators conducted a prospective randomized study to compare axillary minithoracotomy versus a modified two-port thoracoscopic technique for surgical pleurodesis in patients with recurrent spontaneous pneumothorax operated in a single institution. The main objective of the study was to investigate possible differences regarding short- and long-term clinical outcome between the two different techniques.

NCT ID: NCT01135004 Recruiting - Pneumothorax Clinical Trials

Pathogenesis of Primary Spontaneous Pneumothorax

Start date: March 2010
Phase: N/A
Study type: Observational

Primary spontaneous pneumothorax most commonly occurs in young, tall, lean males. The estimated recurrence rate is 23-50% after the first episode and increases to 60% after the second pneumothorax. The pathogenesis of this benign disease remains unclear. Generally, rupture of the emphysematous change or blebs in the apex of the lung is considered as the cause of pneumothorax. The main purpose of this study is to investigate the molecular pathogenesis of blebs formation or emphysematous change of the lung in these young, healthy patients.

NCT ID: NCT01127880 Completed - Pneumothorax Clinical Trials

Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax

Start date: July 2005
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.