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Pleural Effusion clinical trials

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NCT ID: NCT01673165 Completed - Clinical trials for Chylous Pleural Effusion Following Cardiothoracic Surgery

Fortified Skimmed Mother's Milk in the Management of Chylothorax

Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the use of fortified skimmed mother's milk is a safe alternative to specialized formula in the treatment of chylothorax following cardiothoracic surgery.

NCT ID: NCT01670786 Completed - Clinical trials for Pleural Effusion, Malignant

Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion

Start date: January 2010
Phase: Phase 4
Study type: Interventional

Iodopovidone is safe when using as a pleurodesis sclerosing agent for malignant pleural effusion, with minimal adverse events, especially reducing dose.

NCT ID: NCT01661790 Completed - Clinical trials for Malignant Pleural Effusion

Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer

Start date: August 2009
Phase: Phase 3
Study type: Interventional

To determine the efficacy and Safety of intrapleural Bevacizumab and cisplatin as a treatment for malignant pleural effusions (MPE) in patients with non-small cell lung cancer (NSCLC).

NCT ID: NCT01652521 Not yet recruiting - Pleural Effusion Clinical Trials

Effects of Pleural Effusion Drainage on Respiratory System Mechanics

Start date: July 2012
Phase: N/A
Study type: Observational

The effects of pleural drainage on lung mechanics are unknown. Insertion of esophageal balloon will allow us to measure and assess pleural pressure, and thus assess any possible effects of pleural fluid drainage may have on lung mechanics.

NCT ID: NCT01616264 Completed - Tuberculosis Clinical Trials

Reproducibility of Computed Tomography

Start date: January 2006
Phase: N/A
Study type: Observational

Thus, the aim of this study was to evaluate the reproducibility of the Computed Tomograph scan three-dimensional reconstruction method for the measurement of the TB pleural effusion volume in clinically stable patients.

NCT ID: NCT01612975 Terminated - Pleural Effusion Clinical Trials

The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection

Start date: April 2014
Phase: Phase 2
Study type: Interventional

Following a lung resection procedure, patients have their pleural space drained of fluid that accumulates due to the severing of proximal vessels like lymph nodes. The volume of fluid pumped depends on the severity of the inflammation. The investigators are conduction this study to attempt to use painkillers with intrinsic anti-inflammatory action to try and reduce the degree of inflammation in patients' pleural cavity, thus ensuring patients are discharged faster, with a greater comfort level, and a hopefully lower rate of admission.

NCT ID: NCT01601444 Not yet recruiting - Pleural Effusion Clinical Trials

Detection of Pleural Effusion by Internal Thoracic Impedance Method

Start date: June 2012
Phase: N/A
Study type: Interventional

Early detection of pleural effusion (PLE) would improve the treatment. However, preclinical detection of pleural effusion is often not possible. Radiographic examination, widely used for detecting pleural effusion ,is not suitable for prolonged monitoring of patients at high risk of developing PLE especially ambulatory or at home The currently available methods for monitoring and early detection such as the measurement of pulmonary capillary wedge pressure or measurement by double indicator thermodilution, are not reliable enough and may themselves lead to complications. Measuring internal thoracic impedance (ITI), the main component of which is lung impedance, is a noninvasive and safe method. PLE will be diagnosed in accordance with well-accepted clinical signs(dyspnea, cyanosis, pulmonary rales, crepitations, arterial hypoxemia) and roentgenological criteria

NCT ID: NCT01580618 Terminated - Pleural Effusion Clinical Trials

Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy

Start date: January 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of the study is to determine the safety and efficacy of TNK infusion for the treatment of loculated pleural effusions in patients with known malignancy compared to normal saline infusion.

NCT ID: NCT01560078 Completed - Tuberculosis Clinical Trials

Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural Effusion

Start date: September 2006
Phase: N/A
Study type: Observational

Tubercular pleural effusion is the second most common form of extrapulmonary tuberculosis (EPTB) seen in clinical practice after tuberculosis (TB) lymphadenitis. It is common that after complete treatment of the patient with tubercular pleural effusion with six months of the short-course chemotherapy under Directly Observed Treatment Short-Course (DOTS), pleural effusion has not resolved completely. In these cases treatment need to be extended for one or two more months by giving extension pouches. Since DOTS does not recommend demonstration of complete resolution of tubercular pleural effusion at the end of treatment completion, there is paucity of data in terms of the patients declared cure for the sputum negative pulmonary and extra-pulmonary TB as such which includes TB pleural effusion as well. This project aims to look into the patient characteristics, treatment outcome, and compute the number of cases which require an extended regimen and to what extent is the pleural effusion persistent at the end of six months of standard DOTS therapy.

NCT ID: NCT01552187 Active, not recruiting - Atrial Fibrillation Clinical Trials

COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial)

COPPS-2
Start date: March 2012
Phase: Phase 3
Study type: Interventional

This is a multicenter, double-blind, randomized trial to assess the efficacy and safety of colchicine for post-pericardiotomy syndrome prevention, post-operative effusions prevention, and post-operative atrial fibrillation prevention.