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Pleural Effusion clinical trials

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NCT ID: NCT06436807 Not yet recruiting - Pleural Effusion Clinical Trials

PMCF Study of the CE-marked Drainova® ArgentiC Catheter

Start date: May 2024
Phase:
Study type: Observational

The goal of this observational study is to learn about the performance of the drainova® ArgentiC Catheter in clinical routine, which is used to treat fluid accumulations in hollow body structures. The device is already on the market and participants receive the catheter as part of their regular treatment. The main questions of this study are: - Does the device function as intended? - Are there any other safety risks that have not been identified? - Does it lower the symptoms of the patients as intended? Doctors and patients will answer questions regarding the improvement of the patients´ symptoms and if there were any problems with the catheter.

NCT ID: NCT06390969 Not yet recruiting - Pleural Effusion Clinical Trials

TBP Survey Among Respiratory Physicians

Start date: June 1, 2024
Phase:
Study type: Observational

Tuberculosis is a major infectious disease with a high mortality burden in the Asia-Pacific region and worldwide. Among various types of extrapulmonary tuberculosis, tuberculous pleuritis (TBP) is amongst the most common manifestations. TBP is also a major underlying cause among patients hospitalised with new-onset unilateral pleural effusion. The workup of TBP frequently involves thoracentesis to retrieve pleural fluid and pleural biopsy for microbiological and histological interpretations. However, the diagnostic accuracy of these tests is of unsatisfactory sensitivity, making diagnosing TBP challenging. In addition, certain tests, including pleural fluid adenosine deaminase (ADA), Mycobacterium tuberculosis polymerase chain reaction (MTB PCR), advanced biopsy procedures (e.g. real-time image-guided biopsy, pleuroscopy) are not readily available in developing regions due to scarcity of resources and lack of expertise. All these factors lead to heterogeneous practice in approaching new-onset pleural effusion, interpretation of pleural TB investigations, and timing of TBP treatment initiation among respiratory physicians in different Asia-Pacific regions. The proposed multinational survey aims to understand the real-world clinical practice in approaching patients with new-onset unilateral pleural effusion and diagnosing TBP in Asia-Pacific regions with intermediate to high TB burden. The results will reflect the current practice of diagnosing TBP, clinical and resource discrepancies in investigating TBP, management of TBP and help prioritise the need for further research in TBP

NCT ID: NCT06275178 Not yet recruiting - Pleural Effusion Clinical Trials

Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective Study

Start date: March 20, 2024
Phase:
Study type: Observational

This study is a national multicenter retrospective study. Patients with unexplained pleural effusion who underwent thoracoscopic or video-assisted thoracoscopic biopsy for patients in recent 10 years were retrospectively collected from multiple centers to understand the proportion and final etiological composition of pleural effusion in China.

NCT ID: NCT06210685 Not yet recruiting - Pleural Effusion Clinical Trials

The ACES Study for Aseptic Pleural Effusion

Start date: April 2024
Phase: N/A
Study type: Interventional

The study will enroll recurrent aseptic pleural effusion patients who are designated by their physician as needing treatment to control the fluid. Baseline assessment will include a history and physical, chest imaging and quality of life questionnaires. After ACES implantation, patients will remain under hospital care for general observation as per standard-of-care before being discharged home with access to electronic diaries for tracking pain and dyspnea.

NCT ID: NCT06099054 Not yet recruiting - Pleural Effusion Clinical Trials

Ultrasound-guided Pigtail Catheter Versus Intercostal Tube Drainage of Non-traumatic Exudative Pleural Effusion

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Primary Aims: To compare the performance of pigtail catheter to that of ICT in drainage of pleural effusion of medical aetiology regarding: 1. Various complications(mainly wound pain) that result from either therapeutic approach. 2. Success of complete drainage. 3. Compare the duration needed for complete drainage. Secondary Aims: To evaluate both techniques in terms of: 1. Degree of patient's mobility that either technique permits. 2. Percentage of patients that can be managed on outpatient settings by either approach

NCT ID: NCT06066398 Not yet recruiting - Clinical trials for Disorder of Pleura and Pleural Cavity

Thoracoscopic Pleural Lavage and Brushing in Undiagnosed Pleural Effusion

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

1. To evaluate the diagnostic yield and safety of thoracoscopic pleural lavage and pleural brushing in cases of undiagnosed exudative pleural effusion.

NCT ID: NCT05960747 Not yet recruiting - Pleural Effusion Clinical Trials

Improvement to Perform Thoracocentesis After a Specific Training in Medical Students With the Supervised Use of an Augmented Reality Simulator

ARPEGES
Start date: February 2024
Phase:
Study type: Observational

Monocentric study, aiming to assess the improvement of medical students to perform a first-time thoracentesis after training using a specific training using an augmented virtual reality simulator, versus standard training. Study population: medical students from the department of Respirology (University hospital of Strasbourg), performing their first thoracocentesis in patients having an indication for a first-time thoracocentesis. This is not an interventional study, no change in patient course being induced because of the study. After the procedure: use of specific surveys for the patient and for medical students to assess the patient's pain, the patient and the medical student level of anxiety, and the student ability during the procedure.

NCT ID: NCT05693727 Not yet recruiting - Clinical trials for Pleural Effusion, Malignant

Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion

Start date: September 1, 2023
Phase:
Study type: Observational

To evaluate the ability of cancer ratio and pleural fluid markers to discriminate between malignant and non malignant effusion

NCT ID: NCT05642091 Not yet recruiting - Pleural Effusion Clinical Trials

Role of Ultrasound Elastography in Pleural Effusion

Start date: December 13, 2022
Phase: N/A
Study type: Interventional

Diagnostic performance of u.s elastography in pleural effusion

NCT ID: NCT05641779 Not yet recruiting - Pleural Effusion Clinical Trials

Pigtail Catheter for Drainage of (Pneumothorax/Simple Effusion) is a Effective Procedure

pigtail
Start date: December 2022
Phase:
Study type: Observational [Patient Registry]

Assessment and evaluation of Pigtail application in drainage of pneumothorax and haemothorax.