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Plaque clinical trials

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NCT ID: NCT03421145 Completed - Plaque Clinical Trials

A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis

Start date: December 17, 2017
Phase:
Study type: Interventional

Rinse contains an anti-plaque agent that helps prevent the accumulation of dental plaque associated with gingivitis.

NCT ID: NCT03214406 Completed - Gingivitis Clinical Trials

Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis

Start date: February 8, 2010
Phase: N/A
Study type: Interventional

Parallel, double blind, randomized, Institutional Review Board (IRB) -approved study involving approximately 160 subjects to complete. Subjects were randomly assigned to either the test product (Arm & Hammer Advance White Brilliant Sparkle) or the control (Crest Cavity Protection Regular) based on baseline mean whole-mouth plaque and gingival scores and age.Subjects brushed with their assigned dentifrice two times (2X) daily and were evaluated for gingivitis, bleeding and plaque at Baseline and after 4-, 8-, and 12-weeks of product use. Return to pre-study hygiene regimen for 4 weeks and final evaluation at 16 weeks.

NCT ID: NCT03099551 Active, not recruiting - Gingivitis Clinical Trials

Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control

Start date: December 2016
Phase: Phase 4
Study type: Interventional

The aim of the present study was to evaluate the efficacy of two different toothbrushes (manual and sonic) on plaque control

NCT ID: NCT03022344 Active, not recruiting - Diabetes Clinical Trials

DD2-Coronary Plaque Morphology and Plaque Progression

DD2plaque
Start date: November 2014
Phase: N/A
Study type: Interventional

However, there is only very sparse information regarding the atherosclerotic burden and cardiovascular biomarkers in the early stages of type-2 diabetes, as the vast majority of studies have concerned diabetes populations with more than 5 years average diabetes age or high-risk subgroups, who at inclusion already had atherosclerotic disease manifestations. Consequently, this study aims on evaluating the occurrence of early-stage subclinical atherosclerosis in newly diagnosed type-2 diabetes with special emphasis on coronary plaque characteristics by modern imaging techniques. These findings will be compared to the functional status of various peripheral arterial segments and biomarkers in the cross-sectional part of this study. The 5-year follow-up study intends to describe relationships between these selected measures for general atherosclerotic involvement and the progression of the coronary atherosclerotic burden by contemporary techniques.

NCT ID: NCT02980497 Completed - Gingivitis Clinical Trials

Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study

Start date: September 2013
Phase: N/A
Study type: Interventional

The objective of this randomized, single-center, examiner-blind, controlled, parallel group, six-month clinical study is to compare the antiplaque/antigingivitis potential of a no-alcohol essential oil containing mouthrinse and an alcohol essential oil containing mouthrinse. A negative control group using only an ADA Accepted anticavity toothpaste will be included.

NCT ID: NCT02666508 Completed - Inflammation Clinical Trials

Trial of Toothpaste to Reduce Plaque and Inflammation

Start date: September 1, 2015
Phase: N/A
Study type: Interventional

Dental plaque causes caries and periodontal disease and data are sparse about toothpaste and plaque removal. Inflammation, caused by dental plaque, is a risk factor for cardiovascular disease. (CVD) The availability of (Plaque HD (TM), a plaque identifying toothpaste with targetol technology (TM)), afforded the unique opportunity to test whether there were statistically significant and clinically important reductions in plaque and inflammation in a randomized trial of apparently healthy individuals.

NCT ID: NCT02635789 Completed - Plaque Clinical Trials

Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)

Start date: December 2015
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to evaluate the efficacy and safety of NPC-12G gel (topical formulation of sirolimus) versus placebo gel to facial angiofibroma and other skin lesions in patients with tuberous sclerosis complex (TSC)

NCT ID: NCT02634931 Completed - Plaque Clinical Trials

Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex

Start date: December 2015
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to evaluate the safety and efficacy of long-term treatment with NPC-12G gel (0.2% sirolimus gel) to angiofibroma and other skin lesions in patients with tuberous sclerosis complex in the open-label trial.

NCT ID: NCT02574221 Completed - Gingivitis Clinical Trials

A Pilot Study to Evaluate a Molecular Method for Plaque

Start date: August 2015
Phase: N/A
Study type: Interventional

This study is to evaluate the sensitivity of the molecular method and its ability to split a stannous fluoride toothpaste versus a negative control.

NCT ID: NCT02543060 Completed - Gingivitis Clinical Trials

A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice

Start date: June 2015
Phase: N/A
Study type: Interventional

This study will evaluate the sensitivity of an assay and its ability to split a marketed stannous fluoride toothpaste versus a negative control.