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Plaque clinical trials

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NCT ID: NCT06427499 Not yet recruiting - Gingivitis Clinical Trials

The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.

Start date: June 2024
Phase: Phase 3
Study type: Interventional

Qualified subjects will be enrolled and randomly assigned to either of the two study groups based on their initial Plaque and Gingivitis scores. During the first visit, subjects will undergo three key procedures: 1) evaluation for baseline plaque and gingivitis, 2) brushing with the assigned regimen products for two minutes, and 3) assessment for post-brushing plaque only. Subjects will be provided with clear instructions for regimen product usage and will be expected to adhere to these instructions. Follow-up evaluations for plaque and gingivitis will be conducted at one week, six weeks, and three months after initiation of regimen product use. Throughout the study period, continuous monitoring for adverse events will be carried out for all subjects.

NCT ID: NCT05031260 Not yet recruiting - Gingivitis Clinical Trials

COMORAL® the Oral Irrigation Unit Clinical Trial

COMORAL
Start date: October 1, 2021
Phase: N/A
Study type: Interventional

This is a clinical study to evaluate the safety and effectiveness of COMORAL®, the intraoral water-spraying cleaning device that is developed to remove plaque around teeth in the oral cavity. To do so, 42 healthy subjects, 21 control and 21 experimental, will be recruited. To establish the baseline, all subjects will receive dental hygiene service. After 2 weeks, patients will be randomly assigned to either control or intervention group (21 individuals each). Both groups will be asked to brush their teeth once a day but without dental floss, mouth rinse, and gum chewing, throughout the 4 weeks of study period. During the study period, the experimental group will receive COMORAL® treatment three times a day every day for 4 weeks except Saturday and Sunday. Subjects will get evaluated for the oral status(PI, BOP, GI, PD, GR, CAL) and the status of periopathogens on visit 1, visit 2 and visit 3.

NCT ID: NCT04197427 Not yet recruiting - Gingivitis Clinical Trials

Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Since over 50% of the US population have gingivitis, mouthrinses serve as a valuable adjunct to brushing and flossing. The primary objective is to determine the effectiveness of the oral rinse in reducing plaque and gingivitis and improve a patient's breath

NCT ID: NCT03877705 Not yet recruiting - Plaque Clinical Trials

Xylitol Chewable Tablets Versus Xylitol Chewing Gum in Geriatric Bedridden Patients

Start date: September 1, 2019
Phase: Early Phase 1
Study type: Interventional

This study will be conducted to evaluate the effectiveness of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.

NCT ID: NCT01750801 Not yet recruiting - Inflammation Clinical Trials

Efficacy of a Mouthwash Containing Propolis

PRO
Start date: February 2013
Phase: Phase 3
Study type: Interventional

Characterization of green propolis and development of mouthwash containing propolis to control plaque and gingivitis. A Phase I.