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Periodontitis clinical trials

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NCT ID: NCT04399135 Active, not recruiting - Periodontitis Clinical Trials

Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket

Start date: February 25, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the accuracy of pulp test in teeth presenting with deep periodontal pocket. The null hypothesis is no significant effect of periodontitis on the accuracy of pulp test.

NCT ID: NCT04392804 Active, not recruiting - Periodontitis Clinical Trials

Efficacy of Intraseptal Anesthesia of 4% Articaine With Epinephrine Achieved by Computer-controlled Delivery System

EISAAECCLAD
Start date: May 19, 2020
Phase:
Study type: Observational

The aims of our study were to evaluate the clinical anesthetic parameters of the intraseptal anesthesia (ISA), achieved by computer-controlled local anesthetic delivery system CCLADS, for scaling and root planing, as a primary outcome of the study. In addition, as secondary outcome of the study the impact of destruction of the periodontal supporting tissues on clinical anesthetic parameters of the ISA achieved by 4% articaine with 1:100,000 epinephrine, using CCLAD system.

NCT ID: NCT04390997 Completed - Periodontitis Clinical Trials

Determination of the Levels of Lipocalin-2 and Semaphorin3A

Start date: November 15, 2019
Phase: N/A
Study type: Interventional

The aim of this clinical trial is to investigate the concentrations of Lipocalin-2 and Semaphorin 3A levels in gingival crevicular fluid in subjects with different periodontal diseases. At the same time for the periodontitis group; the purpose of this study is to analyze the correlation of these proteins with clinical parameters at the first and third months after the nonsurgical periodontal treatment.

NCT ID: NCT04390789 Recruiting - Clinical trials for Apical Periodontitis

Single And Multiple-visit Endodontic Retreatment Outcome.

Start date: December 15, 2019
Phase: N/A
Study type: Interventional

This study will compare the outcome of single visit retreatment and multi-visit retreatment in cases of failed root canal treated teeth.

NCT ID: NCT04389931 Completed - Periodontitis Clinical Trials

Effect of Omega 3 as an Immunomodulator Adjunct to Periodontal Debridement

Start date: March 2016
Phase: N/A
Study type: Interventional

This study evaluates the effect of the systemic administration of Omega 3 as a therapy associated with non-surgical periodontal treatment, in the clinical and microbiological variables of patients with Moderate Periodontitis with moderate rate of progression (Stage II grade B) and Severe Periodontitis with potential for additional tooth loss and moderate rate of progression (Stage III grade B). A double-blind, randomized, controlled trial was conducted with 18 voluntary patients with a history of moderate to severe chronic periodontitis, who met the inclusion and exclusion criteria and signed an informed consent. The intervention group received Scaling and Root Planning (SRP) plus Omega 3, and the control group received SRP plus placebo. Probing depth (PD), Clinical Attachment Level (CAL), Biofilm Index (BI) and Bleeding on Probing (BOP) were evaluated as clinical variables while Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), Fusobacterium nucleatum (Fn) were the microbiological variables detected by conventional Polymerase chain reaction (PCR).

NCT ID: NCT04389346 Recruiting - Clinical trials for Chronic Apical Periodontitis

A Cone Beam Computed Tomographic Evaluation of Healing of Apicomarginal Defects Using Autologous Platelet Aggregates

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

This study will evaluate the effect of PRF (platelet rich fibrin) on the healing of apicomarginal defects. Healing of the defects will be assessed 2 dimensionaly by periapical radiograph and 3 dimensionaly using CBCT.

NCT ID: NCT04383561 Completed - Inflammation Clinical Trials

Relationship Between LRG and Periodontal Disease

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

This study aimed to investigate gingival crevicular fluid (GCF) and serum levels of LRG, interleukin (IL)-6 and tumor necrosis factor (TNF)-α in patients with periodontitis before and after non-surgical periodontal treatment.

NCT ID: NCT04382261 Completed - Periodontitis Clinical Trials

Impact of Periodontal Bacteria at Baseline on the Effectiveness of Periodontal Therapy

Start date: June 5, 2018
Phase: N/A
Study type: Interventional

In light of the controversy that are already approved but that however still exists regarding the efficacy and influence of the protocols for the management of Periodontitis, the aim of this study was to evaluate, at 6 months follow-up, the post-treatment clinical parameters and immunological and gingival microbial profiles in patients with periodontitis, treated by either SRP in addition to full mouth scaling or quadrant scaling

NCT ID: NCT04382105 Completed - Clinical trials for Periodontal Diseases

Evaluation of Saliva IL-6 Levels and Periodontitis

Start date: November 8, 2015
Phase:
Study type: Observational

The aim of this study was to analyze the association between salivary IL-6 levels in patients with periodontitis. Furthermore, the objective was to determine if the periodontitis influenced salivary IL-6 levels

NCT ID: NCT04381598 Recruiting - Periodontitis Clinical Trials

Stevia Rebaudiana Bertoni on Levels of GCF Glucose and Bio-markers in Diabetics.

Start date: April 1, 2019
Phase: Phase 2
Study type: Interventional

With the increase in the incidence of diabetes and obesity, among other artificial sweeteners the need of natural non-caloric sweetener with acceptable taste and without any adverse effects is demanding.So,the use of stevia presents beneficial effects to general and oral health and its properties could result potentially effective in the treatment of periodontal diseases.