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Periodontal Diseases clinical trials

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NCT ID: NCT04382105 Completed - Clinical trials for Periodontal Diseases

Evaluation of Saliva IL-6 Levels and Periodontitis

Start date: November 8, 2015
Phase:
Study type: Observational

The aim of this study was to analyze the association between salivary IL-6 levels in patients with periodontitis. Furthermore, the objective was to determine if the periodontitis influenced salivary IL-6 levels

NCT ID: NCT04381403 Completed - Clinical trials for Periodontal Diseases

Development of a New Toothpaste for the Removal of Dental Calculus.

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Periodontal disease is amongst the most prevalent oral diseases worldwide and in North America. According to the 2007/09 Canadian Health Measures Survey, 16% of Canadian adults and 24% of older adults, 60 to 79 years of age, were found to have moderate periodontal disease. Moreover, 11% of Canadian adults were found to have calculus scores in the highest range. On the other hand, recent reports on the prevalence of periodontitis in the US showed that 47.2% of adults aged 30 years and older have some form of periodontal disease and 70.1% of adults 65 years and older have periodontal disease. The estimates also showed that the expenditure for periodontal treatments in the US is about approximately $ 14.3 billion. Since dental calculus plays an important etiological role in initiation and progression of periodontal diseases. Investigation and investment on preventive technologies to prevent the periodontal disease are important for any health care system and its end-users. Furthermore, the removal and prevention of dental calculus using an effective toothpaste could reduce the need for professional periodontal interventions or the time of these treatments that in turn reduces their cost and other burdens on patients. The aim of this study is to assess the efficacy of D-Tart toothpaste in removing dental calculus compared to Crest® (Complete Whitening plus Scope, tartar control, Procter & Gamble, Cincinnati, OH), anti-tartar toothpaste with similar pH and texture to D- Tart toothpaste.

NCT ID: NCT04381273 Completed - Covid-19 Clinical Trials

Oral Health and Psychosocial Factors During the Covid-19 Pandemic

Start date: May 15, 2020
Phase:
Study type: Observational

This prospective observational study examines the effects of the Covid-19 pandemic on oral health, taking psychosocial factors into account, and the possible impact of a high periodontitis risk on the severity of the need for treatment in Covid-19 patients.

NCT ID: NCT04380922 Completed - Clinical trials for Inflammatory Bowel Diseases

Prevalence of Periodontal Diseases in IBD

MICIMaP
Start date: June 19, 2020
Phase:
Study type: Observational

Periodontal diseases are highly prevalent inflammatory diseases. It is now well known that they are correlated with numerous systemic diseases as : diabetes, chronic obstructive pulmonary disease, metabolic syndrome or rheumatoid arthritis. Recently, periodontal diseases have been correlated with inflammatory bowel diseases (IBD). IBD include two types, Crohn's disease and Ulcerative Colitis. It could be a significant risk factor for the pathogenesis of periodontal disease. These diseases present common features : a high prevalence worldwide, multifactorial pathogenies with common mechanisms. To date, no study has linked activity of IBD and periodontal diseases. The authors hypotheses that the prevalence of periodontal diseases could be increased in patient presenting an active IBD

NCT ID: NCT04356391 Completed - Clinical trials for Periodontal Diseases

Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession

Start date: January 24, 2018
Phase: N/A
Study type: Interventional

This study compares the efficacy of root coverage achieved by the Pinhole Surgical Technique (PST) technique and the Connective Tissue Graft (CTG) technique in the treatment of Miller class I and II gingival recession defects. All patients will receive PST in one quadrant and CTG in another quadrant. The hypothesis being tested is: Pinhole Surgical Technique outcomes are not inferior to those of the Connective Tissue Graft surgical technique.

NCT ID: NCT04345744 Completed - Clinical trials for Periodontal Diseases

Evaluation of the Rinse With Chlorhexidine Plus Hyaluronic Acid Mouthwash in Periodontal Surgical Wound Healing

CLOR_3
Start date: January 2016
Phase: N/A
Study type: Interventional

Evaluate the response of the gingival tissues to the use of mouthwash with chlorhexidine and chlorhexidine + hyaluronic acid in terms of healing of the periodontal surgical wound.

NCT ID: NCT04335344 Completed - Clinical trials for Periodontal Diseases

Role of suPAR in Periodontitis and CVD

Start date: February 15, 2015
Phase:
Study type: Observational

soluble urokinase-type plasminogen activator receptor (suPAR) plays a key role in endothelial function and may be a link for the known interaction of periodontitis and cardiovascular disease (CVD). The investigators compared the impact of gingival health, periodontitis (CP), CHD or of both diseases (CP+CHD) on saliva and serum suPAR levels.

NCT ID: NCT04332965 Completed - Clinical trials for Periodontal Diseases

Periostin and Non-Surgical Periodontal Treatment

Start date: January 2017
Phase: N/A
Study type: Interventional

A total of 90 subjects, 30 patients with chronic periodontitis, 30 with gingivitis and 30 periodontally healthy subjects were included. Patients with periodontal disease received non-surgical periodontal treatment. Gingival crevicular fluid periostin levels were assessed at baseline, at the 6th week and the 3rd month after treatment.

NCT ID: NCT04271787 Completed - Clinical trials for Periodontal Diseases

New Periodontal Classification

Start date: March 1, 2019
Phase:
Study type: Observational

A new classification system of periodontal and peri-implant diseases and conditions was proposed by consensus of world experts in 2017. Since then there has been ongoing debates among periodontists regarding the application of the new classification. This study aims to shed light on the current understanding of the new classification among Egyptian periodontists.

NCT ID: NCT04268381 Completed - Clinical trials for Periodontal Diseases

Oral and Systemic aMMP-8 in Periodontal Disease

Start date: January 20, 2020
Phase:
Study type: Observational

Periodontal disease is an inflammatory process that can result in tooth loss and also is considered a modifying factor for systemic health. Matrix metalloproteinase (MMP)-8 is the major collagenase of periodontal tissue breakdown. The aim of the present study is to analyze active (aMMP-8) levels in gingival crevicular fluid (GCF), saliva and serum in the context of new criteria of gingivitis and stage 3 grade C periodontitis.