Periodontal Diseases Clinical Trial
Official title:
Development of Toothpaste for the Removal of Dental Calculus: a Double-blind, Randomized Controlled Trial.
Periodontal disease is amongst the most prevalent oral diseases worldwide and in North
America. According to the 2007/09 Canadian Health Measures Survey, 16% of Canadian adults and
24% of older adults, 60 to 79 years of age, were found to have moderate periodontal disease.
Moreover, 11% of Canadian adults were found to have calculus scores in the highest range. On
the other hand, recent reports on the prevalence of periodontitis in the US showed that 47.2%
of adults aged 30 years and older have some form of periodontal disease and 70.1% of adults
65 years and older have periodontal disease. The estimates also showed that the expenditure
for periodontal treatments in the US is about approximately $ 14.3 billion.
Since dental calculus plays an important etiological role in initiation and progression of
periodontal diseases. Investigation and investment on preventive technologies to prevent the
periodontal disease are important for any health care system and its end-users. Furthermore,
the removal and prevention of dental calculus using an effective toothpaste could reduce the
need for professional periodontal interventions or the time of these treatments that in turn
reduces their cost and other burdens on patients.
The aim of this study is to assess the efficacy of D-Tart toothpaste in removing dental
calculus compared to Crest® (Complete Whitening plus Scope, tartar control, Procter & Gamble,
Cincinnati, OH), anti-tartar toothpaste with similar pH and texture to D- Tart toothpaste.
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