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Pericardial Effusion clinical trials

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NCT ID: NCT05061914 Completed - Clinical trials for Pericardial Effusion

Surgical Options for Management of Pericardial Effusion

Start date: March 1, 2016
Phase: N/A
Study type: Interventional

This is a retrospective descriptive study which will be conducted at Sohag university Hospital, Sohag, Egypt at emergency and cardiothoracic department . It includes all patients with pericardial effusion who diagnosed as temponading pericardial effusion or threatened cardiac temponade , The aim of this work is to clarify the suitability and individualization of each surgical procedure (either subxiphoidal drainage, drainage through thoracotomy or video-assisted thoracoscopic (VATS) pericardiotomy) in treatment and diagnosis of patients presenting with pericardial effusion .

NCT ID: NCT03887286 Completed - Clinical trials for Ventricular Dysfunction

Focused Cardiac Ultrasound

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

To compare the images from standard cardiac ultrasound with images from a small hand-held device; to find out more about the feasibility and accuracy of a small hand-held ultrasound device.

NCT ID: NCT03327688 Completed - Clinical trials for Deep Vein Thrombosis

Point-of-care Ultrasound in Finland

Start date: October 20, 2017
Phase: N/A
Study type: Interventional

This study has two aims. 1. Deep venous thrombosis (DVT) is a common suspected medical condition. If it cannot be excluded clinically and using D-dimer, ultrasound examination is required. An option for traditional radiologist-performed ultrasound is a 2-point compression ultrasound (2-CUS). The safety of this technique is proven. However there does not exist any data on costs comparing traditional and 2-CUS pathways in primary health care. This study will evaluate the total cost of both pathways by conducting a cost-minimization analysis. It will also study the effect of a simple ultrasound education on the referrals to hospital due to suspected DVT. Hypothesis 1: Short education in ultrasound will reduce significantly referrals to hospital and save resources. 2. Length of stay (LOS) in emergency department (ED) is related to increased mortality, morbidity, prolonged hospital stay and probably patient satisfaction. LOS of patients with a point-of-care ultrasound (POCUS) performed by an emergency physician (EP) will be compared to those that have a radiology performed ultrasound examination. Further examination and accuracy of POCUS will be noted. Hypothesis 2: POCUS can shorten LOS significantly in selected clinical conditions

NCT ID: NCT02808897 Completed - Atrial Fibrillation Clinical Trials

Active Clearance of Chest Tubes After Cardiac Surgery: A Prospective Randomized Controlled Study

Start date: November 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectiveness of the PleuraFlow® Active Tube Clearance (ATC) technology in reducing the rate of postoperative atrial fibrillation (POAF) among post cardiac surgery patients and to evaluate the impact of Active Tube Clearance (ATC) on other complications, such as retained blood syndrome (RBS), a composite endpoint including re-exploration for bleeding or tamponade, and interventions for hemothorax, pericardial or pleural effusion.

NCT ID: NCT02260206 Completed - Clinical trials for Pericardial Effusion

Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion

Start date: July 2014
Phase: Phase 4
Study type: Interventional

The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.

NCT ID: NCT02054052 Completed - Clinical trials for Non-small Cell Lung Cancer

Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer

Start date: January 2014
Phase: Phase 2
Study type: Interventional

Malignant pleural or pericardial effusion is common in lung cancer, and intrapleural drugs injection is important in the treatment. Non- cytotoxic drugs include those with a sclerosing effect that produces pleurodesis, which is easy to cause severe chest pain despite of no influence on the following chemotherapy. Tumor angiogenesis is important in producing MPE. Bevacizumab has been administrated locally in treating optic nerve sickness successfully by anti-VEGF mechanism. So we hypothesize that intrapleural bevacizumab is also effective in treating MPE.

NCT ID: NCT02045641 Completed - Heart Disease Clinical Trials

Pleural and Pericardial Effusion Following Open Heart Surgery

IMAGING
Start date: September 2013
Phase: N/A
Study type: Interventional

One of the most common postoperative complications after open cardiac surgery is fluid accumulation between the pleural membranes or in the pericardial sac. This study investigates the consequence of such fluid accumulations on physical performance, recovery-time, cardiac and respiratory complications, and quality of life. Half of the participants will be followed closely and offered fluid drainage at a low threshold, and half of the participants will follow the current postoperative regimen.

NCT ID: NCT01266694 Completed - Clinical trials for Pericardial Effusion

Cochicine Treatment for Post- Operative Pericardial Effusion

POPE2
Start date: April 2011
Phase: Phase 4
Study type: Interventional

Background: The incidence of asymptomatic pericardial effusion is high after cardiac surgery. Objective: To assess whether colchicine is effective in reducing post operative pericardial effusion volume. Design: Multicenter, randomized, double-blind, placebo-controlled study. Intervention : colchicine 1mg vs placebo, once daily for 14 days Setting :10 post operative cardiac rehabilitation centers. Patients: 200 patients at high risk of tamponade because of moderate to large persistent pericardial effusion (grade 2, 3 or 4 on a scale of 0 to 4 measured by echocardiography) more than 7 days after cardiac surgery. Measurements: The main end point will be change in effusion grade after 14 days of treatment. Secondary endpoints include frequency of late cardiac tamponade.

NCT ID: NCT00684125 Completed - Clinical trials for Pericardial Effusion

Evaluation of Different Strategies of Pericardial Drainage After Aortic Valvular Surgery

Blake
Start date: June 2008
Phase: N/A
Study type: Interventional

The incidence of pericardial effusion and late cardiac tamponade after aortic and valvular surgery is higher than after other cardiac surgical procedures. The aim of this study is to evaluate the clinical safety and efficacy of prolonged mediastinal drainage using small, soft silastic drains (Blake drain, Ethicon USA) versus conventional mediastinal drainage using large chest tubes. A prospective randomized trial.

NCT ID: NCT00247052 Completed - Clinical trials for Pericardial Effusion

Non Steroidal Anti Inflammatory Treatment for Post Operative Pericardial Effusion

Start date: March 2006
Phase: Phase 4
Study type: Interventional

The aim of the sudy is to evaluate, through clinical, biological and transthoracic echocardiography follow up, the evolution of post operative (cardiac surgery) pericardial effusion and mostly to evaluate the efficiency of a non steroidal anti inflammatory (NSAID) drug (diclofenac)for this indication.