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Pericardial Effusion clinical trials

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NCT ID: NCT06293924 Not yet recruiting - Clinical trials for Pericardial Effusion

Pericardial Fluid Analysis in Recurrent Pericarditis

PEFLANA
Start date: March 2024
Phase:
Study type: Observational [Patient Registry]

This clinical trial aims to examine the biochemical and cytological features of pericardial effusion during acute and recurrent pericarditis and to understand the molecular factors responsible for pathogenesis. The primary objective of this study is to identify and validate diagnostic criteria in pericardial fluid analysis that can differentiate patients with acute and recurrent pericarditis from those with only pericardial fluid but no inflammation. This study will enroll patients with acute pericarditis who require pericardiocentesis for either diagnostic or therapeutic purposes. Two control groups will also be included: one consisting of patients who need cardiac surgery with a collection of pericardial fluid, and the other consisting of patients who require pericardiocentesis for non-inflammatory pericardial effusion. The purpose of the study is to compare the cell activation status and cytokines present in pericardial fluid during acute pericarditis with those present during other pericardial pathologies.

NCT ID: NCT06159985 Recruiting - Clinical trials for Coronary Artery Disease

Effect of Left Posterior Pericardiotomy for the Prevention of POAF

ELIMINATE-AF
Start date: December 11, 2023
Phase: N/A
Study type: Interventional

This study is planned to evaluate the effect of left posterior pericardiotomy for the prevention of postoperative atrial fibrillation after coronary artery bypass grafting. Eligible patients will be randomized to be created or not to be created the left posterior pericardiotomy at the end of the operation, and the incidence of postoperative atrial fibrillation will be compared.

NCT ID: NCT05146492 Recruiting - Clinical trials for Acute Myocardial Infarction

Pericardial Effusion From Acute Myocardial Infarction: Contributing Factors and Prognosis at One Year (EPERICARDIM)

EPERICARDIM
Start date: July 19, 2021
Phase: N/A
Study type: Interventional

This study aims to clarify, in patients with more or less abundant pericardial effusion in the acute phase of a myocardial infarction, the correlation between the existence of this effusion during the acute phase with clinical parameters, biological, angiographic, therapeutic and with transmurality, extent, microvascular obstruction and intra myocardial hemorrhage found on MRI made beyond one week and before the 3rd month of the constitution of the necrosis.

NCT ID: NCT05077111 Active, not recruiting - Clinical trials for Pulmonary Atelectasis

A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia

VATS
Start date: January 15, 2020
Phase: Phase 4
Study type: Interventional

Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including avoidance of airway trauma and ventilator dependence associated with endotracheal intubation, besides promoting enhanced recovery after surgery and shorter mean hospital stay.

NCT ID: NCT05061914 Completed - Clinical trials for Pericardial Effusion

Surgical Options for Management of Pericardial Effusion

Start date: March 1, 2016
Phase: N/A
Study type: Interventional

This is a retrospective descriptive study which will be conducted at Sohag university Hospital, Sohag, Egypt at emergency and cardiothoracic department . It includes all patients with pericardial effusion who diagnosed as temponading pericardial effusion or threatened cardiac temponade , The aim of this work is to clarify the suitability and individualization of each surgical procedure (either subxiphoidal drainage, drainage through thoracotomy or video-assisted thoracoscopic (VATS) pericardiotomy) in treatment and diagnosis of patients presenting with pericardial effusion .

NCT ID: NCT04472468 Recruiting - Clinical trials for Pericardial Effusion Malignant

Primary Percutaneous Pericardiotomy for Malignant Pericardial Effusion (PMAP)

PMAP
Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Pericardial effusion is a common complication in patients with metastatic malignancy. While pericardiocentesis provide effective relieve from life-threatening situation such as cardiac tamponade, recurrence of pericardial effusion after pericardiocentesis is common. We hypothesize that percutaneous balloon pericardiotomy in addition to standard pericardiocentesis with prolonged drainage can prevent pericardial effusion recurrence in patients with malignant pericardial effusion.

NCT ID: NCT04464655 Recruiting - Clinical trials for Coronary Artery Disease

A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease

Start date: December 12, 2019
Phase:
Study type: Observational

This study aims to identify and assess new CMR techniques that can improve current CMR protocols.

NCT ID: NCT04279327 Recruiting - Ascites Clinical Trials

Cell Block Immunohistochemistry in Effusion Cytology

Start date: April 1, 2020
Phase:
Study type: Observational

Cytology is usually the first step in investigating serous effusions, to either detect or exclude an underlying malignancy. This study will try to answer the need for improved diagnostic yield of cytologic examination by cell block technique and immunohistochemical testing of three markers which are EZH2, Claudin-4 and MOC-31.

NCT ID: NCT03887286 Completed - Clinical trials for Ventricular Dysfunction

Focused Cardiac Ultrasound

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

To compare the images from standard cardiac ultrasound with images from a small hand-held device; to find out more about the feasibility and accuracy of a small hand-held ultrasound device.

NCT ID: NCT03327688 Completed - Clinical trials for Deep Vein Thrombosis

Point-of-care Ultrasound in Finland

Start date: October 20, 2017
Phase: N/A
Study type: Interventional

This study has two aims. 1. Deep venous thrombosis (DVT) is a common suspected medical condition. If it cannot be excluded clinically and using D-dimer, ultrasound examination is required. An option for traditional radiologist-performed ultrasound is a 2-point compression ultrasound (2-CUS). The safety of this technique is proven. However there does not exist any data on costs comparing traditional and 2-CUS pathways in primary health care. This study will evaluate the total cost of both pathways by conducting a cost-minimization analysis. It will also study the effect of a simple ultrasound education on the referrals to hospital due to suspected DVT. Hypothesis 1: Short education in ultrasound will reduce significantly referrals to hospital and save resources. 2. Length of stay (LOS) in emergency department (ED) is related to increased mortality, morbidity, prolonged hospital stay and probably patient satisfaction. LOS of patients with a point-of-care ultrasound (POCUS) performed by an emergency physician (EP) will be compared to those that have a radiology performed ultrasound examination. Further examination and accuracy of POCUS will be noted. Hypothesis 2: POCUS can shorten LOS significantly in selected clinical conditions