Clinical Trials Logo

Peri-implantitis clinical trials

View clinical trials related to Peri-implantitis.

Filter by:

NCT ID: NCT04270396 Completed - Peri-Implantitis Clinical Trials

Early and Late Implant Failure

Start date: October 5, 2017
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to evaluate the early and late implant loss rate in a sample of patients who had received implant-supportive restorative therapy in a university setting. Moreover, the study aimed to identify patient- and implant-related variables for implant failure

NCT ID: NCT04254406 Completed - Peri-Implantitis Clinical Trials

Ten Years Follow up of Peri-implant Surgery

Start date: January 1, 2019
Phase:
Study type: Observational

To report 10-years follow up of patients following the surgical treatment of peri-implantitis and to identify possible risk indicators for the progression of disease during supportive peri-implant therapy.

NCT ID: NCT04251793 Completed - Peri-Implantitis Clinical Trials

Therapeutic Peri-implant Maintenance With Laser Therapy

Start date: July 8, 2019
Phase:
Study type: Observational

The present study represents an extension of the previously concluded randomized clinical trial "Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis" (HUM00124386). The aim of the study is to compare the adjunctive effect of laser over mechanical debridement alone in the maintenance of peri-implant tissues after surgical treatment of peri-implantitis (gum disease around implants).

NCT ID: NCT04249024 Completed - Peri-Implantitis Clinical Trials

Peri-implantitis, Comparing Treatments 970 nm Laser and Mucosal Flap Surgery

Start date: September 25, 2019
Phase: N/A
Study type: Interventional

A clinical trial comparing laser treatment and conventional mucosal flap surgery for treatment of peri-implantitis. The main aim of the study is to evaluate if treatment of peri-implantitis with 970 nm laser combined with scaling and root planning (SRP) is clinically comparable to conventional mucosal flap surgery in terms of pocket probing depth reduction.

NCT ID: NCT04213144 Completed - Peri-Implantitis Clinical Trials

Evaluate the Influence of Electromagnetic Field as an Adjunctive Non Surgical Treatment in Implant With Peri-implantitis

Start date: March 3, 2020
Phase: N/A
Study type: Interventional

the aim of the study is to compare between two non-surgical methods of treatment of peri-implantitis by using debridement and placing an healing abutment with electomagnetic field (MED-Magdent Miniaturized Device) in the test group and Sham healing abutment in the control group ( Sham MED).

NCT ID: NCT04152668 Completed - Peri-Implantitis Clinical Trials

Non-surgical Treatment of Peri-implantitis With and Without Erythritol Air-polishing

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Erythritol is a natural sugar alcohol (a four-carbon polyol) produced by the reduction of erythrose. It is considered safe as food additive and has many of the functional properties that are important for subgingival debridement. Current evidence includes no prospective studies comparing the outcomes of a low abrasive erythritol air-polishing as an adjunctive therapy to conventional titanium and ultrasonic debridement of patients in a maintenance program with peri-implantitis. Thus, the main purpose of this randomized, single-masked controlled trial (RCT) is to assess whether low abrasive erythritol air-polishing has an adjunct effect to conventional non-surgical treatment of peri-implantitis.

NCT ID: NCT04149327 Completed - Clinical trials for Periodontal Diseases

Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment

Start date: August 1, 2012
Phase: Phase 4
Study type: Interventional

The primary objective of this controlled clinical trial is to evaluate the clinical effect of systemic amoxicillin plus metronidazole therapy in conjunction with initial non-surgical treatment of peri-implantitis. The secondary objective is to assess the microbiological effectiveness of this peri-implantitis treatment approach. The present study is a single-blind, randomized controlled clinical trial. Adult patients with at least one endosseous implant in the oral cavity with clinical and radiographical evidence of periimplantitis will be included in this study. Patients with implants affected by peri-implantitis will receive initial periodontal treatment existing of oral hygiene instructions and mechanical cleansing of both implants and remaining dentition. Immediately after initial periodontal therapy patients will be instructed to rinse their mouth with 0.12% chlorhexidine + 0.05% cetylpyridinium chloride without alcohol twice daily during 30 seconds for 2 weeks. Additionally patients will receive a recipe for medication consisting of 500 mg amoxicillin and 500 mg metronidazole to be taken every 8 hours for the following 7 days or no recipe. The main study parameter is the mean peri-implant bleeding score.

NCT ID: NCT04129957 Completed - Peri-Implantitis Clinical Trials

Prediction of Failure of Dental Implants

Start date: December 10, 2018
Phase:
Study type: Observational

The aim of the study is to identify predictors in patient profiles and implant characteristics and to develop and calibrate a prediction model for failure of implants. Patients` demographic characteristics, lifestyle habits, general health, dental health, and implant characteristics were regarded as potential predictors. The failure of implants and the follow-up time in days of implants were considered the outcome. Multivariate Cox proportional hazards regression analysis is used to find out the important risk factors for failure of dental implants and to develop the model for prediction of failure of dental implants at follow-up. The performance and clinical values of the model is determined.

NCT ID: NCT04042194 Completed - Peri-Implantitis Clinical Trials

Comparison of CTG and T-PRF on Peri-Implant Soft Tissue

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

The present study aimed to increase the thickness of the gingiva and prevent possible crestal bone resorption by placing the CTG or T-PRF membrane under the mucosa immediately after the implant treatment in individuals with thin gingival phenotype. The null hypothesis was that T-PRF used simultaneously with implant placement can be considered an alternative to CTG.

NCT ID: NCT04020146 Completed - Periodontitis Clinical Trials

PPAR, RXR, and VDR Expressions in Peri-implantitis

Start date: January 10, 2018
Phase:
Study type: Observational

ABSTRACT Objective: Periodontitis and peri-implantitis are the irreversible destructive diseases of the periodontal and peri-implant tissues. The present study aimed to determine the receptor expressions of Peroxisome proliferative-activated receptor (PPAR)-γ, Retinoid X receptor (RXR)-α, and Vitamin D receptor (VDR) in the diseased tissues around teeth and dental implants. Methods: The study consisted of three groups as group 1; healthy controls (C, n=15), group 2; periodontitis patients with stage 3 grade B (P, n=15), and group 3; peri-implantitis patients (PI, n=15). Periodontal clinical parameters as the plaque index (PI), gingival index (GI) and clinical attachment levels (CAL) were recorded. Gingival biopsies were obtained from all participants and biopsy samples underwent histological tissue processing. Hematoxylin-eosin (H&E) and immunohistochemistry staining were performed. Total inflammatory cell counts and fibroblast cell density were evaluated on H&E-stained slides while PPAR-γ, RXR-α, and VDR were evaluated via immunohistochemistry.