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Perfusion; Complications clinical trials

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NCT ID: NCT04424069 Recruiting - Myopia Clinical Trials

OCTA Analysis of Macular and Papillary Perfusion After Refractive Surgery in Myopes

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Refractive surgery for correction of myopia is very common nowadays. However, various refractive techniques may be associated with increase in the IOP, especially during flap creation. It is assumed that marked intraoperative IOP increase lead to macular and optic disc head circulation compromise. The purpose of this study is to assess the change of macular and papillary perfusion, using optical coherence tomography angiography (OCTA) imaging of the macula and optic disc of myopic patients before and after various refractive surgery methods.

NCT ID: NCT04144166 Completed - Clinical trials for Perfusion; Complications

Evaluation of Capillary Refill Index

CRI
Start date: October 29, 2019
Phase:
Study type: Observational

Comparison of a peripheral perfusion assessment method using a pulse oximeter to the conventional capillary refill time visually assessed by a clinician.

NCT ID: NCT04081974 Completed - Clinical trials for Perfusion; Complications

Prevalence and Predictors of Distal Limb Ischemia in Minimally Invasive Cardiac Surgery.

Start date: November 25, 2019
Phase:
Study type: Observational

Peripheral arterial cannulation is a necessity for installation of cardiopulmonary bypass in minimally invasive cardiac surgery (MICS). In the vast majority of cases, the femoral artery is the preferred arterial cannulation site. Distal limb hypoperfusion and ischemia can occur in the cannulated limb since antegrade perfusion is not routinely provided. Furthermore, the diameter of the cannula required to maintain adequate cardiopulmonary bypass (CPB) flow is often approaching that of the patient's femoral artery diameter, compromising distal blood flow. The possibility of distal limb ischemia is often raised as a criticism to peripheral cannulation for cardiopulmonary bypass and by extent to minimally invasive cardiac surgery. Ischemia of the lower limb is of high incidence in patients undergoing extracorporeal membrane oxygenation (ECMO) therapy, in which the same femoral cannulation technique is used. Therefore this complication has extensively been described in ECMO literature. However, no clinical trials have been performed in patients undergoing MICS, despite the same cannulation and perfusion route. ECMO patients often differ from MICS patients in morbidity as well as in duration of cannulation. Up to now, one could not observe any clinical sequelae of limb ischemia in MICS patients but a formal study of distal leg perfusion in MICS is recommended to screen its safety and to identify possible risk factors.

NCT ID: NCT03860493 Completed - Clinical trials for Perfusion; Complications

Feasibility of the IC-Flow Device for Fluorescent Perfusion Evaluation During Feasibility of the IC-Flow Device

IC-Flow
Start date: May 15, 2019
Phase:
Study type: Observational

1. Primary Objective: Demonstrate that the IC-Flow Imaging device with Indocyanine Green (ICG) is a feasible technique when visualizing and identifying perfusion of organs when compared to The KARL STORZ VITOM II ICG System during open reconstructive surgical procedures 2. Secondary Objective: 1. Evaluate the mean Assessment of handling properties using The IC- Flow versus The VITOM II. 2. Evaluate the mean Surgeon preference Level using The IC- Flow tower, The IC-Flow Hand-held device versus The VITOM II.

NCT ID: NCT03843307 Terminated - Clinical trials for Perfusion; Complications

Avazzia-University of Texas Southwestern Medical Center-Tennant Biomodulator® PRO Perfusion Study

Start date: April 24, 2019
Phase: N/A
Study type: Interventional

This study is an open label trial designed to test the effectiveness of the Tennant Biomodulator® PRO electrical stimulation device (Avazzia), which uses BEST™ (Bio-Electric Stimulation Technology), on hospital in-patients to improve perfusion in the treated and contralateral limb.

NCT ID: NCT03747731 Recruiting - Clinical trials for Mechanical Ventilation Complication

A Non-invasive Evaluation of Kidney-Lung Interactions

KIDNEY-LUNG
Start date: November 19, 2018
Phase:
Study type: Observational

The present study aims to evaluate, with non-invasive methods, the relationships existing between PEEP and renal perfusion in patients undergoing surgery and requiring ventilatory support and monitoring in intensive care. Renal perfusion will be assessed at baseline (PEEP 0), subsequently ,at the application of progressive increases of PEEP. At the end of the measurements, the implications of the use of PEEP on the renal vascular system will be analyzed.

NCT ID: NCT03716050 Terminated - Clinical trials for Perfusion; Complications

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

Start date: January 30, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized study using a variety of techniques to compare and examine blood flow to the remaining skin after mastectomy. All treatments being used are considered standard of care and are not experimental. The objective is to compare the techniques and the incidence of perfusion related problems in patient's undergoing mastectomy with immediate breast reconstruction.

NCT ID: NCT03715270 Terminated - Clinical trials for Perfusion; Complications

Evaluation of Tissue Oxygen Levels During Breast Reconstruction With a New Surgical Device

Presygen™
Start date: January 30, 2019
Phase:
Study type: Observational

This study is designed to evaluate the information provided to the clinicians by the surgical imaging device. It is also to gain insight on the user interface and how "user friendly" it is to the clinician.

NCT ID: NCT03711916 Completed - Breast Cancer Clinical Trials

Post-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery

Start date: March 17, 2017
Phase: N/A
Study type: Interventional

Low thermal dissection devices have been introduced as a tool to improve surgical outcomes. PlasmaBlade, a low thermal dissection device, has shown to be associated with effective cutting, and significantly lower temperature than traditional electrosurgical dissection device. Thus, low thermal devices would improve flap perfusion by decreasing the thermal injury resulted by the dissection. Looking into the use of low thermal devices in cases of mastectomy and immediate breast reconstruction has not been documented. The aim of this study is to determine if there are clinical flap perfusion, surgical site drainage, and pain scores differences between mastectomy flaps created using low thermal dissection device and those done with the standard care of Bovie cautery in order to warrant a formal study.

NCT ID: NCT03281707 Not yet recruiting - Clinical trials for Perfusion; Complications

NIRS and DO2i Correlation

Start date: September 30, 2017
Phase: N/A
Study type: Observational [Patient Registry]

This study evaluates the association between near infrared spectroscopy (NIRS) and indexed oxygen delivery (DO2i) and their possible correlation with postoperative organ failure.