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Perfusion; Complications clinical trials

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NCT ID: NCT06254833 Recruiting - Clinical trials for Perfusion; Complications

Microdosing ICG for Serial Colonic Perfusion Study During Surgery

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

using microdosing of ICG vs regular dosing of ICG for perfusion assessment during surgery

NCT ID: NCT06047158 Recruiting - Stomach Neoplasms Clinical Trials

Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer

Start date: December 1, 2022
Phase:
Study type: Observational

The purpose of this study was to investigate the effects of omega-3 fish oil fat emulsion on peripheral blood C-reactive protein, total lymphocyte count, plasma albumin and immune function after radical surgery combined with intraperitoneal hyperthermic perfusion chemotherapy in patients with locally advanced gastric cancer. at the same time, to explore the effects of omega-3 fish oil fat emulsion on complications, length of stay and total cost of hospitalization. The main question it aims to answer is whether the use of omega-3 fish oil fat emulsion can improve patients' immunity, speed up recovery and reduce costs. Participants will comprehensively collect patient-related baseline data, including sex, age, BMI, ASA grade, tumor location, histological grade, pathological tumor type, pTNM stage (AJCC cancer stage 8), and perilymphatic vascular / nerve infiltration. Immune function evaluation related index: peripheral blood lymphocyte count. Plasma albumin concentration, C-reactive protein, postoperative infectious complications, length of stay and cost of hospitalization. Finally, statistical analysis software was used to analyze the differences between the two groups, evaluate the above indicators and draw mutual conclusions.

NCT ID: NCT06019546 Recruiting - Acute Kidney Injury Clinical Trials

PErfusion QUality ODds

PEQUOD
Start date: January 23, 2023
Phase:
Study type: Observational

Cardiac surgery-associated acute kidney injury (CSA-AKI) is a frequent complication after cardiac operations with cardiopulmonary bypass (CPB) use. Its frequency varies depending on the severity grade. There are different "static" predictive scores for the CSA-AKI based on the patient and surgery-associated parameters. Recently, in our Institution was developed a predictive algorithm for CSA-AKI that starts with a static model and then integrated with 7 CPB-associated parameters: HCT, DO2, time of exposure to a critical DO2, systemic pressure, CPB duration time, lactate value, transfusion of red blood cells (RBC), that together build a dynamic perfusion risk (DPR) associated to the CPB. Combining the static and dynamic models produces the Multifactorial Dynamic Perfusion Index (MDPI). The present study validates MDPI in a new prospective series of patients undergoing cardiac surgery with CPB.

NCT ID: NCT05492968 Recruiting - Cardiac Output, Low Clinical Trials

The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic Performance

RACE
Start date: September 1, 2022
Phase: Phase 4
Study type: Interventional

The use of catecholamines for blood pressure and hemodynamic management is essential during undergoing surgery. The type of the catecholamine with the most clinical meaningful effect is still unknown. Therefore, the investigators evaluate the effect of intraoperative continuous infusion of epinephrine, norepinephrine and phenylephrine on intraoperative cardiac output. The investigators further evaluate the effect of epinephrine, norepinephrine and phenylephrine on regional brain and regional tissue oxygenation during surgery.

NCT ID: NCT05276167 Recruiting - Clinical trials for Intraoperative Complications

Hyperthermic Intravesical Perfusion for Muscle-invasive Bladder Urothelial Carcinoma

Start date: June 6, 2022
Phase: N/A
Study type: Interventional

To evaluate the effect of hyperthermic intravesical perfusion on the risk of intraoperative implantation of muscle-invasive bladder urothelial carcinoma and its safety.

NCT ID: NCT04929873 Recruiting - Clinical trials for Perfusion; Complications

Clinical Study of VA-ECMO Remote Limb Re-perfusion Monitoring Technology

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Establish and verify the feasibility and effectiveness of VA-ECMO remote limb re-perfusion monitoring technology.

NCT ID: NCT04424069 Recruiting - Myopia Clinical Trials

OCTA Analysis of Macular and Papillary Perfusion After Refractive Surgery in Myopes

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Refractive surgery for correction of myopia is very common nowadays. However, various refractive techniques may be associated with increase in the IOP, especially during flap creation. It is assumed that marked intraoperative IOP increase lead to macular and optic disc head circulation compromise. The purpose of this study is to assess the change of macular and papillary perfusion, using optical coherence tomography angiography (OCTA) imaging of the macula and optic disc of myopic patients before and after various refractive surgery methods.

NCT ID: NCT03747731 Recruiting - Clinical trials for Mechanical Ventilation Complication

A Non-invasive Evaluation of Kidney-Lung Interactions

KIDNEY-LUNG
Start date: November 19, 2018
Phase:
Study type: Observational

The present study aims to evaluate, with non-invasive methods, the relationships existing between PEEP and renal perfusion in patients undergoing surgery and requiring ventilatory support and monitoring in intensive care. Renal perfusion will be assessed at baseline (PEEP 0), subsequently ,at the application of progressive increases of PEEP. At the end of the measurements, the implications of the use of PEEP on the renal vascular system will be analyzed.