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Pelvic Organ Prolapse clinical trials

View clinical trials related to Pelvic Organ Prolapse.

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NCT ID: NCT03582410 Completed - Clinical trials for Pelvic Organ Prolapse

Different Types of Suture for Sacral Colpopexy

Start date: July 10, 2018
Phase: N/A
Study type: Interventional

This randomized controlled study is designed to test absorbable suture compared to non absorbable suture in laparoscopic sacral colpopexy in terms of anatomical correction of the prolapse, post-operative and long term morbidity, rate of recurrence, subjective satisfaction of the patient and rate of mesh erosion.

NCT ID: NCT03573752 Completed - Clinical trials for Pelvic Organ Prolapse

Study of Outpatient Management for Promontofixation by Laparoscopy

Start date: July 26, 2018
Phase: N/A
Study type: Interventional

Laparoscopic promontofixation is becoming increasingly common and is currently the standard surgical procedure for pelvic prolapse, with few complications including exposure and mesh infection. The research hypothesis is that laparoscopic promontofixation is a relatively painless procedure and can be performed on an outpatient basis without increasing the number of postoperative complications and impairing patients' quality of life. The objective of this study is to evaluate the number of rehospitalizations after management of promontofixation by laparoscopy on an outpatient basis. To evaluate the feasibility of a postoperative H8 exit after laparoscopic promontofixation. Each patient will complete a questionnaire on the experience of management, both in terms of pain management, anxiety and overall satisfaction.

NCT ID: NCT03553511 Not yet recruiting - Clinical trials for Pelvic Organ Prolapse

Laparoscopic Hysterectomy With Vaginal Vault Suspension to the Uterosacral Ligaments for Stage II-III Pelvic Organ Prolapse.

LULS-1
Start date: May 2022
Phase: N/A
Study type: Interventional

The International Continence Society defines post-hysterectomy vault prolapse (PHVP) as descent of the vaginal cuff scar below a point that is 2 cm less than the total vaginal length above the plane of the hymen. The incidence of PHVP has been reported to affect up to 43% of hysterectomies. The risk of prolapse following hysterectomy is 5.5 times more common in women whose initial hysterectomy was for pelvic organ prolapse as opposed to other reasons. Techniques available to manage PHVP aim to ultimately suspend the vaginal vault. Approaches include vaginal, e.g. uterosacral ligament suspension, sacrospinous ligament fixation, open procedures and more recently laparoscopic, e.g. sacrocolpopexy and uterosacral plication. Data published so far do not allow to draw a firm conclusion about the best treatment to prevent PHVP for women undergoing hysterectomy for stage II-III pelvic organ prolapse. Considering this scenario, in the current study the investigators aim to evaluate short and long-term outcomes after total laparoscopic hysterectomy with vaginal vault suspension to the uterosacral ligaments versus vaginal hysterectomy with McCall culdoplasty for the treatment of stage II-III pelvic organ prolapse.

NCT ID: NCT03539107 Completed - Clinical trials for Urinary Incontinence

Voiding Assessment Based on Minimum Spontaneous Void of 150 mL Compared to Retrograde Fill Method After Female Pelvic Floor Reconstructive Surgery

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This study will compare voiding assessment based on a minimum spontaneous voided volume of 150 cc with the standard retrograde fill approach in women after pelvic floor procedures.

NCT ID: NCT03534830 Completed - Prolapse Genital Clinical Trials

A Novel Assay for Predicting Surgical Outcomes in Pelvic Organ Prolapse

eLASV
Start date: February 2, 2018
Phase:
Study type: Observational

The research objective of this proposal is to investigate the clinical utility and validity of eLASV as a personalized marker for women's individual risk of recurrence for pelvic organ prolapse following advanced surgical procedures. Estimated levator ani subtended volume (eLASV) is a reproducible magnetic resonance image of the female pelvis that objectively quantifies the integrity of the pelvic floor levator ani muscles. A woman's levator ani muscle anatomical shape is unique to her as a result of her own individual lifetime risk for development of pelvic floor dysfunction. The novelty of eLASV as a measurement of muscle integrity, separates it methodology from the solitary of diagnosing partial trauma or defects as previously published within the literature. eLASV measurements have the potential to identify women at increased risk for surgical failure and may be used as a prognostic tool to aid in future counseling and stratification of patients into surgical options for treatment of pelvic organ prolapse.

NCT ID: NCT03524339 Completed - Clinical trials for Pelvic Organ Prolapse

Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery

Start date: August 1, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is a placebo controlled randomized controlled trial of perioperative use of tamsulosin to prevent postoperative urinary retention in female pelvic reconstructive surgery.

NCT ID: NCT03522961 Active, not recruiting - Clinical trials for Urinary Incontinence

Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery

Start date: August 15, 2018
Phase: N/A
Study type: Interventional

We aim to compare the effectiveness of cranberry capsules versus nitrofurantoin prophylaxis in preventing urinary tract infections (UTIs) after urogynecologic surgery by conducting a double-blinded randomized clinical trial involving women with pelvic organ prolapse and/or urinary incontinence scheduled to have surgery with the Urogynecologists who comprise the Brigham and Women's Urogynecology Group.

NCT ID: NCT03516136 Completed - Clinical trials for Pelvic Organ Prolapse

Safety and Performance of the EndoFast Reliant SCP in Vaginal Wall Reinforcement

Start date: January 1, 2015
Phase:
Study type: Observational

A Single arm, single site, retrospective cohort Post Marketing Clinical Follow up Study Evaluating the Safety and Performance of the EndoFast Reliant SCP for apical support.

NCT ID: NCT03498443 Recruiting - Clinical trials for Female Sexual Dysfunction

Effect of Pelvic Organ Prolapse Surgeries on Female Sexual Function in Egyptian Women

Start date: September 1, 2017
Phase:
Study type: Observational

study on female sexual function after different prolapse surgeries

NCT ID: NCT03487328 Completed - Clinical trials for Uterovaginal and Vaginal Vault Prolapse

A New Technique for Sacrospinous-Sacrotuberous Fixation for the Treatment of Uterovaginal and Vaginal Vault Prolapse

Start date: March 21, 2018
Phase: N/A
Study type: Interventional

This prospective interventional randomized controlled trial is conducted to compare a new technique for Sacrospinous-Sacrotuberous fixation with the traditional sacrospinous ligament fixation technique for treatment of uterovaginal and vaginal vault prolapse.