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Pelvic Organ Prolapse clinical trials

View clinical trials related to Pelvic Organ Prolapse.

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NCT ID: NCT06461234 Recruiting - Clinical trials for Pelvic Organ Prolapse

Pelvic Floor Rehabilitation of Female Pelvic Floor Dysfunction

Start date: May 20, 2024
Phase:
Study type: Observational

The goal of this observational study is to learn about the therapeutic effects of different pelvic floor rehabilitation treatments, including pelvic floor muscle training , pelvic floor biofeedback electrical stimulation, and magnetic stimulation, in a population of Chinese patients with female pelvic floor dysfunction disorders. The study aims to find out the individualised pelvic floor rehabilitation treatment plan suitable for the Chinese population. The main question it aims to answer is: 1. Do patients with reduced pelvic floor muscle strength after childbirth, or patients with mild to moderate pelvic organ prolapse and symptomatic pelvic organ prolapse benefit from pelvic floor rehabilitation? 2. Is the combination of biofeedback electrical stimulation plus pelvic floor magnetic stimulation superior to single electrical stimulation, magnetic stimulation or pelvic floor muscle training? 3. Which pelvic floor rehabilitation therapy is most suitable for Chinese patients with female pelvic floor dysfunction? 4. What factors are early predictors of developing female pelvic floor dysfunction? And what factors can predict the prognostic status of patients treated with pelvic floor rehabilitation? Participants in the multicenter will be treated with different rehabilitation therapies, during which the researchers will collect clinical symptoms using the PFDI20 questionnaire, and POP-Q scores, pelvic floor muscle strength, and electromyography results from participants before, at the end of, and 3 months and 1 year after the end of treatment.

NCT ID: NCT06369857 Recruiting - Clinical trials for Pelvic Organ Prolapse

Pectopexy for Apical Prolapse Management

Start date: May 9, 2024
Phase: N/A
Study type: Interventional

This study was designed to evaluate the efficacy of pectopexy for treatment of apical pelvic organ prolapse at follow up at 12 months. Investigator also evaluates complications, improvement of symptoms, quality-of-life outcomes and patient satisfaction with surgery. Assessment of restoration of normal pelvic anatomy and lower urinary tract symptoms using transperineal ultrasound

NCT ID: NCT06363903 Recruiting - Clinical trials for Pelvic Organ Prolapse

ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantation

Start date: May 9, 2022
Phase:
Study type: Observational

In the present pilot study, a possible relation between the implantation of PP mesh for inguinal hernia, vaginal prolapse and SUI repair and subsequent systemic auto-immune complaints is investigated by testing immunologic and allergic responses in fifty patients with suspected ASIA syndrome. Additional value of MAT is investigated and effectiveness of (partial) PP mesh removal for these complaints is assessed. If so, a profound insight in diagnostics and treatment for systematic complaints will be attained that may provide opportunities for future diagnostics.

NCT ID: NCT06341088 Recruiting - Clinical trials for Pelvic Organ Prolapse

Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro-hysteropexy Operations

Start date: April 5, 2024
Phase: N/A
Study type: Interventional

The study was planned as prospective and randomized. For the study, patients will be randomized into two groups as unilateral and bilateral suture sacro-hysteropexy operations.

NCT ID: NCT06260436 Recruiting - Clinical trials for Pelvic Organ Prolapse

Questionnaire of Lower Urinary Tract Symptoms Among Women Before and After Surgical Correction of Uterine Prolapse

Start date: May 30, 2021
Phase:
Study type: Observational

. The study will include patients who underwent Pelvic reconstructive surgery for advanced pelvic organ prolapse (POP-Q ≥ 3). Data regarding preoperative evaluation, surgical procedure, and post-operative management will be collected. women will receive a follow up questionnaire. . The baseline questionnaire included data on age, urinary incontinence, daytime frequency, nocturia, postmicturition dribble, straining, urgency, incomplete bladder emptying, and hesitancy. Women were asked about leakage caused by coughing or sneezing, moving, lifting, sleeping, sexual intercourse, urgency, and rest.

NCT ID: NCT06253689 Recruiting - Clinical trials for Pelvic Organ Prolapse Vaginal Surgery

Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair

Start date: February 19, 2024
Phase: N/A
Study type: Interventional

This study will determine if defecation posture, when using a defecation posture modification device (DPMD), improves ease with first bowel movement following pelvic reconstructive surgery, specifically posterior repair.

NCT ID: NCT06246721 Recruiting - Clinical trials for Pelvic Organ Prolapse

Attitude and Success Rate of Women With Pelvic Organ Prolapse on Self-management of Vaginal Pessary

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

This is a prospective cohort study aims at assessing patient's attitude towards self-management of vaginal pessary, and identifying factors that affect patient's level of acceptance towards self-management.

NCT ID: NCT06245577 Recruiting - Clinical trials for Pelvic Organ Prolapse

Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP

BioSynIRS
Start date: January 30, 2024
Phase: N/A
Study type: Interventional

The purpose of the pilot study is to demonstrate the safety and efficacy of a biological mesh compared to a standard synthetic mesh for the planned procedure in the above-mentioned clinical picture. Subsequently, a multicentre, randomized intervention study is planned to confirm the results and evaluate the long-term outcomes.

NCT ID: NCT06176521 Recruiting - Clinical trials for Pelvic Organ Prolapse

Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Evaluation of the anatomical and functional results of laparoscopic sacrohysteropexy and sacrocolpopexy surgeries performed without using mesh in the surgical treatment of pelvic organ prolapse

NCT ID: NCT06120530 Recruiting - Clinical trials for Pelvic Organ Prolapse

Intraperitoneal Bupivacaine for Pelvic Organ Prolapse

Start date: August 15, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of 30 mL intraperitoneal Bupivacaine without epinephrine 0.25% on postoperative pain control in patients undergoing pelvic organ prolapse repair. The investigators hypothesize that use of intraperitoneal Bupivacaine will decrease postoperative pain scores and opiate consumption in the postoperative period, following pelvic organ prolapse repair.