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Pediatric Oncology clinical trials

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NCT ID: NCT05867186 Recruiting - Pediatric Oncology Clinical Trials

Fit to Fight Childhood Cancer

Kolibri
Start date: June 20, 2023
Phase:
Study type: Observational

The aim of the study is to investigate the influence of exercise on physical performance and psychosocial aspects in children and adolescents with cancer during and after treatment.

NCT ID: NCT05691816 Completed - Pediatric Oncology Clinical Trials

The Experience of the Child With Cancer When Port à Cath Needle : Child's Speech

ELEAPort
Start date: January 1, 2022
Phase:
Study type: Observational

This qualitative research refers to the descriptive phenomenological method of Hurssel which allows an analysis of the experience and an understanding of the phenomenon. Semi-structured interviews are carried out with 10 children followed for cancer in 3 pediatric hemato-oncology departments. The children interviewed are aged 6 to 12 and can be with their parents. A thematic analysis approach is used to analyze the data of this research.

NCT ID: NCT05289739 Recruiting - Pediatric Oncology Clinical Trials

Exercise Training in Childhood Cancer

FORTEe
Start date: April 25, 2022
Phase: N/A
Study type: Interventional

The purpose of this multicenter study is to evaluate a personalised and standardised exercise intervention for children and adolescents undergoing anti-cancer treatment.

NCT ID: NCT03650530 Completed - Pediatric Oncology Clinical Trials

The Family Talk Intervention in Pediatric Oncology

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Even though most children with cancer now survive the ill child has to go through painful treatments which include suffering and uncertainty for all family members. The overall aim is to evaluate a modified version of the Family Talk Intervention (FTI) among families affected by childhood cancer. The goals of FTI are to increase family communication, the family members' resilience, knowledge about the illness, and thereby reduce the family members' long-term psychosocial well-being. Specific aims are to assess the feasibility (Aim 1) and the possible effects of the FTI (Aim 2). Two to three months after diagnosis families at one of six pediatric oncology units in Sweden will be recruited to FTI. All families at this unit who have a child (with cancer and/or sibling) in the age of 6 to 19 will be asked to participate. The recruitment will continuing for 9 months. The core elements in the intervention are to support: 1) the families in talking about the illness and related subjects, 2) the parents in understanding the needs of their children and how to support them, and 3) the families in identifying their strengths and how to use them. FTI entails six meetings with two interventionists (with the whole family and with the individual members of the family) at 1-2 weekly intervals. Questionnaires, interviews and field notes will be used to evaluate the intervention. Time points for data collection: before the intervention starts (baseline), directly after the intervention (follow-up 1) and 6 months after baseline (follow-up 2). Since few intervention studies (if any) of this kind have been carried out in pediatric oncology in Sweden to date, this study fills a knowledge gap. Research has described how cancer affects the whole family, and the importance of an open and honest communication about the illness in order to reduce the psychological suffering. The interventions presented here are likely to improve communication within the family, which may reduce the risk of long-term psychological distress for all family members.

NCT ID: NCT03593525 Completed - Quality of Life Clinical Trials

SPARK Symptom Screening and Feedback to Providers

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK) is a web-based application which builds upon the Symptom Screening in Pediatrics Tool (SSPedi) and consists of two components: (1) a symptom screening component centered on SSPedi; and (2) a supportive care clinical practice guideline (CPG) component. This proposal is a randomized controlled trial that compares daily completion of SSPedi via SPARK for 5 days with symptom feedback to healthcare providers compared with standard of care

NCT ID: NCT02612025 Completed - Pediatric Oncology Clinical Trials

Effects of Resistance and Endurance Training in Pediatric Cancer Patients During Intensive Treatment Phase

MUCKI
Start date: November 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether combined endurance and resistance training can improve muscle strength in children and adolescents with cancer during the intensive treatment phase.

NCT ID: NCT02085148 Active, not recruiting - Pediatric Oncology Clinical Trials

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Start date: April 11, 2014
Phase: Phase 1
Study type: Interventional

Dose escalation phase of the study : To define the safety profile, maximum tolerated dose (MTD) and recommended phase II dose (RP2D) of regorafenib administered orally as a single agent in a 3-weeks-on/1- week-off schedule in repeating cycles of 28 days in pediatric subjects with solid malignant tumors recurrent or refractory to standard therapy. To characterize the pharmacokinetics (PK) of regorafenib The dose escalation phase of the study has been completed. Expansion phase: To define the safety profile, MTD and the RP2D of regorafenib administered orally in combination with backbone chemotherapy (vincristine and irinotecan) at relapse in pediatric subjects with rhabdomyosarcoma (RMS) and other solid malignant tumors recurrent or refractory to standard therapy.