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Pathologic Processes clinical trials

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NCT ID: NCT03510104 Active, not recruiting - Neoplasms Clinical Trials

Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors

Start date: May 22, 2018
Phase: Phase 1
Study type: Interventional

This first-in-human open-label, dose escalation study is designed to evaluate the safety, tolerability, and PK of MRX-2843 in subjects with relapsed/refractory advanced and/or metastatic solid tumors.

NCT ID: NCT03417791 Active, not recruiting - Clinical trials for Kidney; Functional Disturbance

Recovery of Serum Creatinine at Discharge Impacts Mortality

RECOST
Start date: January 1, 2007
Phase: N/A
Study type: Observational

The aim of our study is to assess the mortality in the in-hospital patients who have elevated serum creatinine. A registry of patients with increased serum creatinine during hospital was conducted at the Guangdong General Hospital from January 1st, 2007 to December 30th, 2013. The primary clinical outcome is all-cause mortality, followed from the date of hospital discharge to Dec 30th 2018. Patients were divided into three groups, according to the serum creatinine recovery ratio (discharge/max serum creatinine). All-cause mortality, including the date of death, was identified from the electronic hospitalization data, phone follow-up, and confirmed by the household registration (HUKOU) system, a record of registration required by law in China. Baseline characteristics, including primary disease diagnosis, blood pressure, major treatment, drug use and et al, were collected. Demographic data were collected from the electronic hospitalization data and electronic hospital discharge records. All co-morbid conditions were identified using International Statistical Classification of Diseases, Tenth Revision (ICD-10), coding algorithms applied to electronic physician claims and electronic hospital discharge records.

NCT ID: NCT02973893 Active, not recruiting - Clinical trials for Cardiovascular Diseases

Study of VF001-DP in Patients With Chronic Venous Leg Ulcers

Start date: November 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if VF001-DP improves wound healing in chronic venous leg ulcers compared to standard care only.

NCT ID: NCT02768311 Active, not recruiting - Clinical trials for Pain, Postoperative Pain Pathologic Processes Postoperative Complications Signs and Symptoms

Comparative Evaluation of Post Endodontic Pain Following Root Canal Treatment With Two Rotary System: Neolix & Waveone

Start date: May 2016
Phase: N/A
Study type: Interventional

Today, dentists tend to use rotary systems. Despite the increasing diversity of these systems as well as a few studies on the prevalence of pain after root canal treatment by rotary systems, And in particular, comparing the amount of pain after treatment, between systems RECIPROCAL AND FULL ROTATION single-file, the aim of this study was to evaluate the effect of applying canal preparation by the system, Neolix and WaveOne, on the prevalence of pain after endodontic treatments.

NCT ID: NCT02685098 Active, not recruiting - Clinical trials for Cardiovascular Disease

A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

CHAMP
Start date: January 23, 2017
Phase: Phase 1
Study type: Interventional

Patients undergoing semi-elective lower extremity major amputation from complications associated with atherosclerotic limb ischemia will received intra-muscular injections of allogeneic Mesenchymal Stromal Cells in the leg above and below the point of amputation to prevent ischemic wound complications after surgery and decrease the incidence of revision and further amputation. Cohort Groups 1-4 will serve as controls.

NCT ID: NCT02437240 Active, not recruiting - Clinical trials for Other Functional Disturbances Following Cardiac Surgery

Pilates-based Cardiopulmonary Physical Therapy for In-Patients After Cardiac Surgery

PBCPT
Start date: August 2014
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to evaluate the effect of pilates-based cardiopulmonary physical therapy (CPT) for in-patients after cardiac surgery.

NCT ID: NCT01579110 Active, not recruiting - Anemia Clinical Trials

Efficacy and Safety of Levamisole Combined With Standard Prednisolone in Warm Antibody Autoimmune Hemolytic Anemia.

Start date: April 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether Levamisole plus prednisone can further improve the efficacy,extend the remission duration and reduce the dosage of prednisone for newly diagnosed warm antibody autoimmune hemolytic anemia.